WZ4002 - Small Molecule (ID:10085-101)
| HMS LINCS ID: |
10085-101
|
| Name: | WZ4002 |
| Alternative Names: | |
| LINCS ID: | LSM-1085 |
| PubChem CID: | 44607530 |
| ChEBI ID: | |
| ChEMBL ID: | |
| Molecular Mass: | 494.18 |
| InChi: | InChI=1S/C25H27ClN6O3/c1-4-23(33)28-17-6-5-7-19(14-17)35-24-20(26)16-27-25(30-24)29-21-9-8-18(15-22(21)34-3)32-12-10-31(2)11-13-32/h4-9,14-16H,1,10-13H2,2-3H3,(H,28,33)(H,27,29,30) |
| InChi Key: | ITTRLTNMFYIYPA-UHFFFAOYSA-N |
| SMILES: | CN1CCN(CC1)C2=CC(=C(C=C2)NC3=NC=C(C(=N3)OC4=CC=CC(=C4)NC(=O)C=C)Cl)OC |
| Relevant Citations: | |
| Comments: | |
| Date Publicly Available: | |
| Most Recent Update: | 2016-04-04 |
Target Affinity:
(see Study 20000)| Target Affinity Spectrum Value | HUGO Gene Name |
|---|---|
EGFR, ERBB2, ERBB3, ERBB4 | |
2 (equivalent to 100 nM ≤ Kd < 1µM) | BTK, JAK3, PTK2 |
10 (confirmed non-binding) |
Datasets:
| HMS Dataset ID | Dataset Title | HMS Dataset Type |
|---|---|---|
| 20000 | Target Affinity Spectrum (TAS) vectors for compounds in the HMS LINCS small molecule library. | Analysis |
| 20069 | WZ4002 KINOMEscan | KINOMEscan |
KINOMEscan Image
Batch Information:
| HMS LINCS Batch ID | Provider | Provider Batch ID |
|---|---|---|
| 10085-101-1 | Nathanael Gray (DFCI) | WZ4002-1 |
(Kd <100 nM)