KU55933 - Small Molecule (ID:10074-101)
| HMS LINCS ID: |
10074-101
|
| Name: | KU55933 |
| Alternative Names: | |
| LINCS ID: | LSM-1074 |
| PubChem CID: | 5278396 |
| ChEBI ID: | |
| ChEMBL ID: | |
| Molecular Mass: | 395.06 |
| InChi: | InChI=1S/C21H17NO3S2/c23-14-12-16(25-20(13-14)22-8-10-24-11-9-22)15-4-3-7-19-21(15)27-18-6-2-1-5-17(18)26-19/h1-7,12-13H,8-11H2 |
| InChi Key: | XRKYMMUGXMWDAO-UHFFFAOYSA-N |
| SMILES: | C1COCCN1C2=CC(=O)C=C(O2)C3=C4C(=CC=C3)SC5=CC=CC=C5S4 |
| Relevant Citations: | |
| Comments: | |
| Date Publicly Available: | |
| Most Recent Update: | 2016-04-04 |
Target Affinity:
(see Study 20000)| Target Affinity Spectrum Value | HUGO Gene Name |
|---|---|
ATM | |
2 (equivalent to 100 nM ≤ Kd < 1µM) | DYRK1A, GSK3B, MAP3K11, MAPK15, PIM1, PIM3 |
3 (equivalent to 1µM ≤ Kd < 10 µM) | MTOR, PRKDC |
10 (confirmed non-binding) |
Datasets:
| HMS Dataset ID | Dataset Title | HMS Dataset Type |
|---|---|---|
| 20000 | Target Affinity Spectrum (TAS) vectors for compounds in the HMS LINCS small molecule library. | Analysis |
Batch Information:
| HMS LINCS Batch ID | Provider | Provider Batch ID |
|---|---|---|
| 10074-101-1 | Tocris | 3544-1 |
(Kd <100 nM)