AS601245 - Small Molecule (ID:10034-101)

HMS LINCS ID: 10034-101
Name: AS601245
Alternative Names: JNK Inhibitor V
LINCS ID: LSM-1034
PubChem CID: 10109823
ChEBI ID:
ChEMBL ID: 191384
Molecular Mass: 372.12
InChi: InChI=1S/C20H16N6S/c21-12-15(19-25-17-5-1-2-6-18(17)27-19)16-8-11-24-20(26-16)23-10-7-14-4-3-9-22-13-14/h1-6,8-9,11,13,15H,7,10H2,(H,23,24,26)
InChi Key: RCYPVQCPYKNSTG-UHFFFAOYSA-N
SMILES: C1=CC=C2C(=C1)N=C(S2)C(C#N)C3=NC(=NC=C3)NCCC4=CN=CC=C4
Relevant Citations:
Comments:
Date Publicly Available:
Most Recent Update: 2016-04-04

Target Affinity:

(see Study 20000)
Target Affinity Spectrum Value HUGO Gene Name
2
(equivalent to 100 nM ≤ Kd < 1µM)
MAPK10, MAPK8, MAPK9

Datasets:

HMS Dataset ID Dataset Title HMS Dataset Type
20000
Target Affinity Spectrum (TAS) vectors for compounds in the HMS LINCS small molecule library.
Analysis
20035
AS601245 KINOMEscan
 KINOMEscan

Batch Information:

HMS LINCS Batch ID Provider Provider Batch ID
10034-101-1 Nathanael Gray (DFCI) KIN001-099-1
10034-101-2 Calbiochem
10034-101-3 EMD Millipore D00166235