ALW-II-38-3 - Small Molecule (ID:10002-101)
HMS LINCS ID: | 10002-101 |
Name: | ALW-II-38-3 |
Alternative Names: | |
LINCS ID: | LSM-1002 |
PubChem CID: | 24880028 |
ChEBI ID: | |
ChEMBL ID: | |
Molecular Mass: | 469.14 |
InChi: | InChI=1S/C23H18F3N5O3/c1-13-3-4-17(10-19(13)30-22(33)20-5-6-28-34-20)29-21(32)15-7-16(23(24,25)26)9-18(8-15)31-11-14(2)27-12-31/h3-12H,1-2H3,(H,29,32)(H,30,33) |
InChi Key: | IYUFHBXMTTXZBE-UHFFFAOYSA-N |
SMILES: | CC1=C(C=C(C=C1)NC(=O)C2=CC(=CC(=C2)N3C=C(N=C3)C)C(F)(F)F)NC(=O)C4=CC=NO4 |
Relevant Citations: | |
Comments: | |
Date Publicly Available: | |
Most Recent Update: | 2016-04-04 |
Target Affinity:
(see Study 20000)Target Affinity Spectrum Value | HUGO Gene Name |
---|---|
ABL2, BRAF, CSF1R, DDR1, DDR2, EPHA2, EPHA3, EPHA4, EPHA5, EPHA8, EPHB2, EPHB3, EPHB4, FRK, KIT, MAPK11, MAPK14, PDGFRA, PDGFRB, SRC | |
10 (confirmed non-binding) |
Datasets:
HMS Dataset ID | Dataset Title | HMS Dataset Type |
---|---|---|
20000 | Target Affinity Spectrum (TAS) vectors for compounds in the HMS LINCS small molecule library. | Analysis |
20049 | ALW-II-38-3 KINOMEscan | KINOMEscan |
KINOMEscan Image
Batch Information:
HMS LINCS Batch ID | Provider | Provider Batch ID |
---|---|---|
10002-101-1 | Nathanael Gray (DFCI) | ALW-II-38-3-1 |
(equivalent to 100 nM ≤ Kd < 1µM)