Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SUM149PT | TNBC | Basal B | Valproic acid | HDAC | HDAC | 0.0384 | uM | 11937.143 | 0.9827 | 0.9850 | 2.3169 | |
| SUM149PT | TNBC | Basal B | Valproic acid | HDAC | HDAC | 0.192 | uM | 11937.143 | 0.9920 | 0.9931 | 2.3169 | |
| SUM149PT | TNBC | Basal B | Valproic acid | HDAC | HDAC | 0.96 | uM | 11937.143 | 0.8931 | 0.9047 | 2.3169 | |
| SUM149PT | TNBC | Basal B | Valproic acid | HDAC | HDAC | 4.8 | uM | 11937.143 | 0.9537 | 0.9595 | 2.3169 | |
| SUM149PT | TNBC | Basal B | Valproic acid | HDAC | HDAC | 24 | uM | 11937.143 | 0.9482 | 0.9546 | 2.3169 | |
| SUM149PT | TNBC | Basal B | Valproic acid | HDAC | HDAC | 120 | uM | 11937.143 | 1.0088 | 1.0076 | 2.3169 | |
| SUM149PT | TNBC | Basal B | Valproic acid | HDAC | HDAC | 600 | uM | 11937.143 | 0.8010 | 0.8173 | 2.3169 | |
| SUM149PT | TNBC | Basal B | Valproic acid | HDAC | HDAC | 3000 | uM | 11937.143 | 0.3439 | 0.2617 | 2.3169 | |
| SUM149PT | TNBC | Basal B | Valproic acid | HDAC | HDAC | 15000 | uM | 11937.143 | 0.0080 | -0.7512 | 2.3169 | |
| SUM159PT | TNBC | Basal B | Valproic acid | HDAC | HDAC | 0.0384 | uM | 11057.143 | 0.9678 | 0.9843 | 4.1426 | |
| SUM159PT | TNBC | Basal B | Valproic acid | HDAC | HDAC | 0.192 | uM | 11057.143 | 0.9286 | 0.9646 | 4.1426 | |
| SUM159PT | TNBC | Basal B | Valproic acid | HDAC | HDAC | 0.96 | uM | 11057.143 | 0.9357 | 0.9682 | 4.1426 | |
| SUM159PT | TNBC | Basal B | Valproic acid | HDAC | HDAC | 4.8 | uM | 11057.143 | 0.9759 | 0.9882 | 4.1426 | |
| SUM159PT | TNBC | Basal B | Valproic acid | HDAC | HDAC | 24 | uM | 11057.143 | 0.9718 | 0.9862 | 4.1426 | |
| SUM159PT | TNBC | Basal B | Valproic acid | HDAC | HDAC | 120 | uM | 11057.143 | 0.9154 | 0.9578 | 4.1426 | |
| SUM159PT | TNBC | Basal B | Valproic acid | HDAC | HDAC | 600 | uM | 11057.143 | 0.6761 | 0.8197 | 4.1426 | |
| SUM159PT | TNBC | Basal B | Valproic acid | HDAC | HDAC | 3000 | uM | 11057.143 | 0.2653 | 0.4518 | 4.1426 | |
| SUM159PT | TNBC | Basal B | Valproic acid | HDAC | HDAC | 15000 | uM | 11057.143 | 0.0017 | -0.5710 | 4.1426 | |
| SUM185PE | TNBC | Luminal | Valproic acid | HDAC | HDAC | 0.0384 | uM | 12269.143 | 1.3121 | 3.8208 | 0.3088 | |
| SUM185PE | TNBC | Luminal | Valproic acid | HDAC | HDAC | 0.192 | uM | 12269.143 | 1.3021 | 3.7027 | 0.3088 | |
| SUM185PE | TNBC | Luminal | Valproic acid | HDAC | HDAC | 0.96 | uM | 12269.143 | 0.9475 | 0.6793 | 0.3088 | |
| SUM185PE | TNBC | Luminal | Valproic acid | HDAC | HDAC | 4.8 | uM | 12269.143 | 1.4179 | 5.1973 | 0.3088 | |
| SUM185PE | TNBC | Luminal | Valproic acid | HDAC | HDAC | 24 | uM | 12269.143 | 1.3166 | 3.8744 | 0.3088 | |
| SUM185PE | TNBC | Luminal | Valproic acid | HDAC | HDAC | 120 | uM | 12269.143 | 1.3509 | 4.2976 | 0.3088 | |
| SUM185PE | TNBC | Luminal | Valproic acid | HDAC | HDAC | 600 | uM | 12269.143 | 1.0497 | 1.3405 | 0.3088 |