Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC1187 | TNBC | Basal A | Trichostatin A | HDAC | HDAC | 1000 | uM | 7432.065 | 0.0133 | -0.9911 | 0.7981 | |
| HCC1187 | TNBC | Basal A | Trichostatin A | HDAC | HDAC | 5000 | uM | 7432.065 | 0.0092 | -0.9944 | 0.7981 | |
| HCC1187 | TNBC | Basal A | Trichostatin A | HDAC | HDAC | 0.0128 | uM | 7433.065 | 0.9784 | 0.9511 | 0.8820 | |
| HCC1187 | TNBC | Basal A | Trichostatin A | HDAC | HDAC | 0.064 | uM | 7433.065 | 1.0445 | 1.1011 | 0.8820 | |
| HCC1187 | TNBC | Basal A | Trichostatin A | HDAC | HDAC | 0.32 | uM | 7433.065 | 1.0384 | 1.0872 | 0.8820 | |
| HCC1187 | TNBC | Basal A | Trichostatin A | HDAC | HDAC | 1.6 | uM | 7433.065 | 1.0297 | 1.0675 | 0.8820 | |
| HCC1187 | TNBC | Basal A | Trichostatin A | HDAC | HDAC | 8 | uM | 7433.065 | 0.2281 | -0.6257 | 0.8820 | |
| HCC1187 | TNBC | Basal A | Trichostatin A | HDAC | HDAC | 40 | uM | 7433.065 | 0.0226 | -0.9728 | 0.8820 | |
| HCC1187 | TNBC | Basal A | Trichostatin A | HDAC | HDAC | 200 | uM | 7433.065 | 0.0147 | -0.9833 | 0.8820 | |
| HCC1187 | TNBC | Basal A | Trichostatin A | HDAC | HDAC | 1000 | uM | 7433.065 | 0.0123 | -0.9864 | 0.8820 | |
| HCC1187 | TNBC | Basal A | Trichostatin A | HDAC | HDAC | 5000 | uM | 7433.065 | 0.0112 | -0.9877 | 0.8820 | |
| HCC1395 | TNBC | Basal B | Trichostatin A | HDAC | HDAC | 0.0128 | uM | 7435.065 | 0.9506 | 0.8844 | 0.8513 | |
| HCC1395 | TNBC | Basal B | Trichostatin A | HDAC | HDAC | 0.064 | uM | 7435.065 | 0.7074 | 0.3318 | 0.8513 | |
| HCC1395 | TNBC | Basal B | Trichostatin A | HDAC | HDAC | 0.32 | uM | 7435.065 | 1.0165 | 1.0389 | 0.8513 | |
| HCC1395 | TNBC | Basal B | Trichostatin A | HDAC | HDAC | 1.6 | uM | 7435.065 | 0.9912 | 0.9792 | 0.8513 | |
| HCC1395 | TNBC | Basal B | Trichostatin A | HDAC | HDAC | 8 | uM | 7435.065 | 0.9586 | 0.9031 | 0.8513 | |
| HCC1395 | TNBC | Basal B | Trichostatin A | HDAC | HDAC | 40 | uM | 7435.065 | 0.3097 | -0.4953 | 0.8513 | |
| HCC1395 | TNBC | Basal B | Trichostatin A | HDAC | HDAC | 200 | uM | 7435.065 | 0.1551 | -0.7759 | 0.8513 | |
| HCC1395 | TNBC | Basal B | Trichostatin A | HDAC | HDAC | 1000 | uM | 7435.065 | 0.0872 | -0.8861 | 0.8513 | |
| HCC1395 | TNBC | Basal B | Trichostatin A | HDAC | HDAC | 5000 | uM | 7435.065 | 0.0353 | -0.9606 | 0.8513 | |
| HCC1395 | TNBC | Basal B | Trichostatin A | HDAC | HDAC | 0.0128 | uM | 7436.065 | 0.9859 | 0.9769 | 1.2177 | |
| HCC1395 | TNBC | Basal B | Trichostatin A | HDAC | HDAC | 0.064 | uM | 7436.065 | 0.9857 | 0.9764 | 1.2177 | |
| HCC1395 | TNBC | Basal B | Trichostatin A | HDAC | HDAC | 0.32 | uM | 7436.065 | 1.0156 | 1.0257 | 1.2177 | |
| HCC1395 | TNBC | Basal B | Trichostatin A | HDAC | HDAC | 1.6 | uM | 7436.065 | 0.9952 | 0.9921 | 1.2177 | |
| HCC1395 | TNBC | Basal B | Trichostatin A | HDAC | HDAC | 8 | uM | 7436.065 | 0.9591 | 0.9325 | 1.2177 |