High-content imaging of six breast cancer cell lines treated with a library of small molecule kinase inhibitors. - Dataset (ID:20244)
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| Cell | SM Name | Small Mol Concentration | Small Mol Conc Unit | Other Reagent 1 Name | Other Reagent 1 Detection Channel | Other Reagent 2 Name | Other Reagent 2 Detection Channel | Row | Column | Field | X-coordinate | Y-coordinate | Image | Nuclear area (pixels) | Cytoplasm area (pixels) | Nuclear intensity (AU) | Std Dev of nuclear intensity (AU) | Cytoplasm intensity (AU) | Std Dev of cytoplasm intensity (AU) | 10% quantile of nuclear intensity (AU) | 20% quantile of nuclear intensity (AU) | 30% quantile of nuclear intensity (AU) | 40% quantile of nuclear intensity (AU) | 50% quantile of nuclear intensity (AU) | 60% quantile of nuclear intensity (AU) | 70% quantile of nuclear intensity (AU) | 80% quantile of nuclear intensity (AU) | 90% quantile of nuclear intensity (AU) | Ratio of cytoplasm perimeter to area | Cytoplasm perimeter (pixels) | Nuclear roundness | Nuclear length (pixels) | Nuclear halfwidth (pixels) | Number of nuclei | Ratio of nuclear perimeter to area | Nuclear perimeter (pixels) | Nuclear Haralick ASM | Nuclear Haralick contrast | Nuclear Haralick entropy | Nuclear Haralick IDM | Nuclear Haralick moment 2 | Nuclear Haralick moment 3 | Nuclear Haralick moment 4 | Nuclear Haralick moment 5 | Nuclear radial moment (border) | Nuclear radial moment (center) | Nuclear Threshold Adj Stat 1 (Threshold: 0.2) | Nuclear Threshold Adj Stat 1 (Threshold: 0.4) | Nuclear Threshold Adj Stat 2 (Threshold: 0.2) | Nuclear Threshold Adj Stat 2 (Threshold: 0.4) | Nuclear Threshold Adj Stat 3 (Threshold: 0.2) | Nuclear Threshold Adj Stat 3 (Threshold: 0.4) | Nuclear Threshold Adj Stat 4 (Threshold: 0.2) | Nuclear Threshold Adj Stat 4 (Threshold: 0.4) | Nuclear Threshold Adj Stat 5 (Threshold: 0.2) | Nuclear Threshold Adj Stat 5 (Threshold: 0.4) | Nuclear Threshold Adj Stat 6 (Threshold: 0.2) | Nuclear Threshold Adj Stat 6 (Threshold: 0.4) | Nuclear Threshold Adj Stat 7 (Threshold: 0.2) | Nuclear Threshold Adj Stat 7 (Threshold: 0.4) | Nuclear Threshold Adj Stat 8 (Threshold: 0.2) | Nuclear Threshold Adj Stat 8 (Threshold: 0.4) | Nuclear Threshold Adj Stat 9 (Threshold: 0.2) | Nuclear Threshold Adj Stat 9 (Threshold: 0.4) | Nuclear Threshold Adj Stat 10 (Threshold: 0.2) | Nuclear Threshold Adj Stat 10 (Threshold: 0.4) | Nuclear Threshold Adj Stat 11 (Threshold: 0.2) | Nuclear Threshold Adj Stat 11 (Threshold: 0.4) | Nuclear Threshold Adj Stat 12 (Threshold: 0.2) | Nuclear Threshold Adj Stat 12 (Threshold: 0.4) | Nuclear Threshold Adj Stat 13 (Threshold: 0.2) | Nuclear Threshold Adj Stat 13 (Threshold: 0.4) | Nuclear Threshold Adj Stat 14 (Threshold: 0.2) | Nuclear Threshold Adj Stat 14 (Threshold: 0.4) | Nuclear Threshold Adj Stat 15 (Threshold: 0.2) | Nuclear Threshold Adj Stat 15 (Threshold: 0.4) | Nuclear Threshold Adj Stat 16 (Threshold: 0.2) | Nuclear Threshold Adj Stat 16 (Threshold: 0.4) | Nuclear Threshold Adj Stat 17 (Threshold: 0.2) | Nuclear Threshold Adj Stat 17 (Threshold: 0.4) | Nuclear Threshold Adj Stat 18 (Threshold: 0.2) | Nuclear Threshold Adj Stat 18 (Threshold: 0.4) | Nuclear Threshold Adj Stat 19 (Threshold: 0.2) | Nuclear Threshold Adj Stat 19 (Threshold: 0.4) | Nuclear Threshold Adj Stat 20 (Threshold: 0.2) | Nuclear Threshold Adj Stat 20 (Threshold: 0.4) | Nuclear Threshold Adj Stat 21 (Threshold: 0.2) | Nuclear Threshold Adj Stat 21 (Threshold: 0.4) | Nuclear Threshold Adj Stat 22 (Threshold: 0.2) | Nuclear Threshold Adj Stat 22 (Threshold: 0.4) | Nuclear Threshold Adj Stat 23 (Threshold: 0.2) | Nuclear Threshold Adj Stat 23 (Threshold: 0.4) | Nuclear Threshold Adj Stat 24 (Threshold: 0.2) | Nuclear Threshold Adj Stat 24 (Threshold: 0.4) | Nuclear Threshold Adj Stat 25 (Threshold: 0.2) | Nuclear Threshold Adj Stat 25 (Threshold: 0.4) | Nuclear Threshold Adj Stat 26 (Threshold: 0.2) | Nuclear Threshold Adj Stat 26 (Threshold: 0.4) | Nuclear Threshold Adj Stat 27 (Threshold: 0.2) | Nuclear Threshold Adj Stat 27 (Threshold: 0.4) | Nuclear Threshold Adj Stat 28 | Nuclear Threshold Adj Stat 29 | Nuclear Threshold Adj Stat 30 | Nuclear Threshold Adj Stat 31 | Nuclear Threshold Adj Stat 32 | Nuclear Threshold Adj Stat 33 | Nuclear Threshold Adj Stat 34 | Nuclear Threshold Adj Stat 35 | Nuclear Threshold Adj Stat 36 | 10% quantile of cytoplasm intensity (AU) | 20% quantile of cytoplasm intensity (AU) | 30% quantile of cytoplasm intensity (AU) | 40% quantile of cytoplasm intensity (AU) | 50% quantile of cytoplasm intensity (AU) | 60% quantile of cytoplasm intensity (AU) | 70% quantile of cytoplasm intensity (AU) | 80% quantile of cytoplasm intensity (AU) | 90% quantile of cytoplasm intensity (AU) | Cytoplasmic Haralick ASM | Cytoplasmic Haralick contrast | Cytoplasmic Haralick entropy | Cytoplasmic Haralick IDM | Cytoplasmic Haralick moment 2 | Cytoplasmic Haralick moment 3 | Cytoplasmic Haralick moment 4 | Cytoplasmic Haralick moment 5 | Cytoplasmic radial moment (border) | Cytoplasmic radial moment (center) | Cytoplasmic Threshold Adj Stat 1 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 1 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 2 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 2 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 3 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 3 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 4 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 4 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 5 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 5 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 6 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 6 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 7 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 7 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 8 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 8 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 9 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 9 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 10 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 10 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 11 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 11 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 12 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 12 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 13 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 13 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 14 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 14 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 15 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 15 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 16 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 16 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 17 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 17 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 18 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 18 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 19 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 19 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 20 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 20 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 21 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 21 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 22 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 22 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 23 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 23 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 24 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 24 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 25 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 25 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 26 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 26 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 27 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 27 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 28 | Cytoplasmic Threshold Adj Stat 29 | Cytoplasmic Threshold Adj Stat 30 | Cytoplasmic Threshold Adj Stat 31 | Cytoplasmic Threshold Adj Stat 32 | Cytoplasmic Threshold Adj Stat 33 | Cytoplasmic Threshold Adj Stat 34 | Cytoplasmic Threshold Adj Stat 35 | Cytoplasmic Threshold Adj Stat 36 |
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| Hs 578T | A443654 | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 12 | 1 | 296 | 572 | | 8086 | 26684 | 302.2 | 79.97 | 205.86 | 280.95 | 205 | 239 | 262 | 283 | 304 | 326 | 349 | 373 | 401 | 0.0475 | 1267 | 0.665 | 59.68 | 11.31 | 3 | 0.0177 | 143 | 0.0008 | 40.70 | 7.343 | 0.1978 | 97719.6 | 33200000 | 11800000000 | 4310000000000 | 0.3795 | 0.2472 | 0.0011 | 0.0000 | 0.0016 | 0.0000 | 0.0074 | 0.0003 | 0.0207 | 0.0023 | 0.0767 | 0.0172 | 0.1294 | 0.0437 | 0.1280 | 0.0397 | 0.1701 | 0.0578 | 0.4650 | 0.8391 | 0.0002 | 0.0000 | 0.0006 | 0.0000 | 0.0016 | 0.0000 | 0.0058 | 0.0012 | 0.0212 | 0.0116 | 0.0426 | 0.0234 | 0.0420 | 0.0137 | 0.0672 | 0.0206 | 0.8188 | 0.9295 | 0.0020 | 0.0068 | 0.0051 | 0.0228 | 0.0164 | 0.0387 | 0.0475 | 0.1048 | 0.0915 | 0.2096 | 0.1539 | 0.1891 | 0.1099 | 0.1071 | 0.1595 | 0.1344 | 0.4141 | 0.1868 | 0.0002 | 0.0041 | 0.0090 | 0.0124 | 0.0506 | 0.0812 | 0.0669 | 0.0846 | 0.6910 | 12 | 15 | 18 | 23 | 51 | 133 | 250 | 395 | 618 | 0.1321 | 29.66 | 4.846 | 0.5609 | 121307.0 | 98300000 | 95600000000 | 106000000000000 | 0.3068 | 0.3447 | 0.0442 | 0.0016 | 0.1546 | 0.0133 | 0.2155 | 0.0891 | 0.1482 | 0.1397 | 0.1751 | 0.1708 | 0.1401 | 0.1937 | 0.0636 | 0.1158 | 0.0442 | 0.1223 | 0.0145 | 0.1536 | 0.0006 | 0.0000 | 0.0012 | 0.0004 | 0.0031 | 0.0022 | 0.0115 | 0.0116 | 0.0386 | 0.0343 | 0.0571 | 0.0510 | 0.0451 | 0.0319 | 0.0658 | 0.0520 | 0.7769 | 0.8165 | 0.0007 | 0.0010 | 0.0026 | 0.0022 | 0.0043 | 0.0052 | 0.0155 | 0.0182 | 0.0500 | 0.0581 | 0.0812 | 0.0876 | 0.0644 | 0.0690 | 0.0894 | 0.1000 | 0.6918 | 0.6586 | 0.0002 | 0.0011 | 0.0040 | 0.0169 | 0.0395 | 0.0700 | 0.0579 | 0.0782 | 0.7322 |
| Hs 578T | A443654 | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 12 | 1 | 992 | 554 | | 458 | 453 | 58.6 | 18.24 | 15.98 | 3.18 | 38 | 42 | 46 | 52 | 56 | 61 | 66 | 72 | 84 | 0.4040 | 183 | 0.735 | 110.07 | 27.07 | 1 | 0.6135 | 281 | 0.0119 | 5.25 | 4.713 | 0.4351 | 3769.0 | 265175 | 20300000 | 1680000000 | 0.3546 | 0.2594 | 0.0000 | 0.0000 | 0.0199 | 0.0000 | 0.0448 | 0.0000 | 0.0597 | 0.0052 | 0.1294 | 0.0735 | 0.2139 | 0.1417 | 0.1791 | 0.0761 | 0.1343 | 0.1155 | 0.2189 | 0.5879 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0164 | 0.0046 | 0.0656 | 0.0371 | 0.1049 | 0.0928 | 0.0721 | 0.0278 | 0.0951 | 0.0603 | 0.6459 | 0.7773 | 0.0096 | 0.0000 | 0.0000 | 0.0000 | 0.0096 | 0.0600 | 0.0673 | 0.1800 | 0.2019 | 0.1000 | 0.1731 | 0.2800 | 0.0865 | 0.1400 | 0.1635 | 0.0600 | 0.2885 | 0.1800 | 0.0000 | 0.0000 | 0.0048 | 0.0335 | 0.1435 | 0.1483 | 0.1100 | 0.1627 | 0.3971 | 12 | 13 | 14 | 15 | 16 | 17 | 17 | 18 | 20 | 0.8738 | 0.06 | 0.306 | 0.9702 | 265.5 | 4574.87 | 81636.7 | 1510000 | 0.5349 | 0.1049 | 0.0031 | 0.0000 | 0.0217 | 0.0000 | 0.0683 | 0.0046 | 0.1211 | 0.0207 | 0.2050 | 0.1359 | 0.1739 | 0.1544 | 0.1739 | 0.1613 | 0.1801 | 0.1521 | 0.0528 | 0.3710 | 0.0026 | 0.0000 | 0.0078 | 0.0000 | 0.0284 | 0.0045 | 0.0413 | 0.0089 | 0.1835 | 0.1250 | 0.1550 | 0.1473 | 0.1576 | 0.1518 | 0.1938 | 0.1384 | 0.2300 | 0.4241 | 0.2923 | 0.5000 | 0.1846 | 0.2143 | 0.1385 | 0.2143 | 0.1846 | 0.0714 | 0.1077 | 0.0000 | 0.0615 | 0.0000 | 0.0308 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0195 | 0.0586 | 0.1328 | 0.1445 | 0.1758 | 0.1680 | 0.1367 | 0.1055 | 0.0586 |
| Hs 578T | A443654 | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 12 | 1 | 826 | 768 | | 6744 | 16336 | 268.2 | 71.69 | 141.22 | 168.95 | 172 | 220 | 244 | 260 | 275 | 290 | 307 | 325 | 352 | 0.0586 | 958 | 0.774 | 134.30 | 33.11 | 3 | 0.0550 | 371 | 0.0010 | 38.65 | 7.160 | 0.1905 | 77081.5 | 23200000 | 7220000000 | 2320000000000 | 0.3771 | 0.2521 | 0.0002 | 0.0000 | 0.0005 | 0.0000 | 0.0047 | 0.0000 | 0.0202 | 0.0010 | 0.0641 | 0.0201 | 0.1133 | 0.0421 | 0.1271 | 0.0409 | 0.1690 | 0.0603 | 0.5009 | 0.8356 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0002 | 0.0000 | 0.0022 | 0.0003 | 0.0193 | 0.0134 | 0.0351 | 0.0215 | 0.0430 | 0.0137 | 0.0639 | 0.0228 | 0.8363 | 0.9283 | 0.0020 | 0.0031 | 0.0094 | 0.0282 | 0.0201 | 0.0627 | 0.0602 | 0.1818 | 0.1145 | 0.1567 | 0.1667 | 0.2382 | 0.1245 | 0.1160 | 0.1506 | 0.1097 | 0.3521 | 0.1034 | 0.0005 | 0.0016 | 0.0054 | 0.0231 | 0.0549 | 0.0995 | 0.1012 | 0.1118 | 0.6018 | 11 | 13 | 17 | 33 | 74 | 117 | 174 | 256 | 384 | 0.1123 | 13.02 | 4.544 | 0.6051 | 48483.6 | 23400000 | 14000000000 | 9870000000000 | 0.3529 | 0.3072 | 0.0233 | 0.0006 | 0.0993 | 0.0098 | 0.1771 | 0.0540 | 0.1646 | 0.0816 | 0.1538 | 0.1403 | 0.1514 | 0.1788 | 0.0946 | 0.1438 | 0.0814 | 0.1444 | 0.0545 | 0.2467 | 0.0000 | 0.0000 | 0.0010 | 0.0014 | 0.0024 | 0.0015 | 0.0118 | 0.0068 | 0.0392 | 0.0287 | 0.0668 | 0.0517 | 0.0535 | 0.0373 | 0.0764 | 0.0617 | 0.7488 | 0.8108 | 0.0006 | 0.0011 | 0.0012 | 0.0025 | 0.0052 | 0.0039 | 0.0226 | 0.0215 | 0.0569 | 0.0753 | 0.0967 | 0.1142 | 0.0841 | 0.1007 | 0.1157 | 0.1304 | 0.6171 | 0.5504 | 0.0003 | 0.0014 | 0.0036 | 0.0128 | 0.0544 | 0.0778 | 0.0679 | 0.0958 | 0.6859 |
| Hs 578T | A443654 | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 12 | 1 | 164 | 879 | | 4050 | 8872 | 419.4 | 110.73 | 86.10 | 234.18 | 295 | 334 | 362 | 385 | 409 | 439 | 474 | 515 | 570 | 0.0979 | 869 | 0.960 | 155.00 | 54.01 | 3 | 0.1049 | 425 | 0.0007 | 76.29 | 7.489 | 0.1602 | 188142.0 | 89200000 | 44400000000 | 23100000000000 | 0.4137 | 0.2255 | 0.0004 | 0.0000 | 0.0017 | 0.0000 | 0.0052 | 0.0000 | 0.0231 | 0.0043 | 0.0718 | 0.0210 | 0.1144 | 0.0459 | 0.1271 | 0.0397 | 0.1462 | 0.0559 | 0.5100 | 0.8333 | 0.0003 | 0.0000 | 0.0006 | 0.0000 | 0.0019 | 0.0000 | 0.0071 | 0.0013 | 0.0298 | 0.0149 | 0.0481 | 0.0238 | 0.0528 | 0.0149 | 0.0708 | 0.0245 | 0.7886 | 0.9206 | 0.0011 | 0.0000 | 0.0043 | 0.0099 | 0.0130 | 0.0099 | 0.0444 | 0.0759 | 0.0704 | 0.1452 | 0.1083 | 0.1716 | 0.0986 | 0.1089 | 0.1073 | 0.1584 | 0.5525 | 0.3201 | 0.0016 | 0.0032 | 0.0111 | 0.0185 | 0.0506 | 0.0749 | 0.0611 | 0.0870 | 0.6921 | 11 | 12 | 14 | 15 | 16 | 17 | 20 | 35 | 226 | 0.4982 | 14.49 | 2.220 | 0.8059 | 62249.3 | 81200000 | 135000000000 | 258000000000000 | 0.6303 | 0.0763 | 0.2131 | 0.0132 | 0.4262 | 0.1376 | 0.2295 | 0.3995 | 0.0546 | 0.1508 | 0.0546 | 0.1164 | 0.0219 | 0.1085 | 0.0000 | 0.0423 | 0.0000 | 0.0265 | 0.0000 | 0.0053 | 0.0007 | 0.0006 | 0.0055 | 0.0019 | 0.0097 | 0.0070 | 0.0194 | 0.0171 | 0.0947 | 0.0912 | 0.1418 | 0.1476 | 0.0705 | 0.0646 | 0.0961 | 0.0956 | 0.5615 | 0.5744 | 0.0008 | 0.0008 | 0.0032 | 0.0042 | 0.0071 | 0.0100 | 0.0301 | 0.0308 | 0.1013 | 0.1032 | 0.1362 | 0.1424 | 0.0831 | 0.0849 | 0.1077 | 0.1091 | 0.5305 | 0.5146 | 0.0022 | 0.0037 | 0.0066 | 0.0176 | 0.1051 | 0.1412 | 0.0713 | 0.1037 | 0.5485 |
| Hs 578T | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 324 | 200 | | 9267 | 28546 | 136.9 | 41.75 | 161.87 | 233.98 | 86 | 99 | 112 | 124 | 135 | 146 | 158 | 172 | 193 | 0.0455 | 1300 | 0.914 | 69.01 | 19.70 | 6 | 0.0181 | 168 | 0.0013 | 24.49 | 6.895 | 0.2332 | 20479.4 | 3300000 | 567000000 | 103000000000 | 0.4196 | 0.2164 | 0.0018 | 0.0000 | 0.0058 | 0.0004 | 0.0076 | 0.0017 | 0.0306 | 0.0073 | 0.1008 | 0.0279 | 0.1517 | 0.0559 | 0.1639 | 0.0691 | 0.1899 | 0.0994 | 0.3480 | 0.7382 | 0.0006 | 0.0000 | 0.0024 | 0.0000 | 0.0018 | 0.0004 | 0.0088 | 0.0035 | 0.0321 | 0.0139 | 0.0490 | 0.0251 | 0.0522 | 0.0285 | 0.0722 | 0.0388 | 0.7809 | 0.8897 | 0.0043 | 0.0081 | 0.0086 | 0.0070 | 0.0241 | 0.0252 | 0.0455 | 0.0916 | 0.0769 | 0.1370 | 0.1327 | 0.1631 | 0.1078 | 0.1269 | 0.1430 | 0.1511 | 0.4570 | 0.2900 | 0.0011 | 0.0051 | 0.0058 | 0.0210 | 0.0568 | 0.0917 | 0.0790 | 0.1085 | 0.6310 | 20 | 25 | 32 | 42 | 59 | 88 | 146 | 248 | 465 | 0.0337 | 41.47 | 5.283 | 0.5159 | 80948.0 | 65000000 | 65600000000 | 76000000000000 | 0.5258 | 0.1466 | 0.0551 | 0.0017 | 0.1968 | 0.0211 | 0.2532 | 0.1230 | 0.1516 | 0.1351 | 0.1376 | 0.1940 | 0.0880 | 0.1858 | 0.0596 | 0.1152 | 0.0384 | 0.1031 | 0.0199 | 0.1210 | 0.0003 | 0.0001 | 0.0003 | 0.0004 | 0.0036 | 0.0018 | 0.0190 | 0.0156 | 0.0709 | 0.0590 | 0.1046 | 0.0925 | 0.0709 | 0.0629 | 0.1037 | 0.0968 | 0.6266 | 0.6709 | 0.0006 | 0.0008 | 0.0014 | 0.0019 | 0.0072 | 0.0074 | 0.0231 | 0.0271 | 0.0831 | 0.0907 | 0.1334 | 0.1460 | 0.0842 | 0.0925 | 0.1238 | 0.1209 | 0.5433 | 0.5125 | 0.0008 | 0.0026 | 0.0043 | 0.0227 | 0.0776 | 0.1148 | 0.0780 | 0.1182 | 0.5810 |
| Hs 578T | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 171 | 227 | | 13156 | 26560 | 216.3 | 55.08 | 143.33 | 196.83 | 147 | 172 | 189 | 203 | 217 | 231 | 246 | 263 | 286 | 0.0570 | 1514 | 0.695 | 170.21 | 47.54 | 3 | 0.0364 | 479 | 0.0008 | 42.66 | 7.414 | 0.1765 | 49810.3 | 12100000 | 3040000000 | 797000000000 | 0.4175 | 0.2260 | 0.0007 | 0.0001 | 0.0014 | 0.0001 | 0.0076 | 0.0009 | 0.0228 | 0.0052 | 0.0655 | 0.0153 | 0.1188 | 0.0349 | 0.1344 | 0.0418 | 0.1753 | 0.0659 | 0.4735 | 0.8359 | 0.0000 | 0.0000 | 0.0003 | 0.0000 | 0.0012 | 0.0004 | 0.0075 | 0.0020 | 0.0220 | 0.0098 | 0.0398 | 0.0182 | 0.0480 | 0.0148 | 0.0644 | 0.0241 | 0.8168 | 0.9308 | 0.0028 | 0.0282 | 0.0118 | 0.0267 | 0.0277 | 0.0847 | 0.0602 | 0.1278 | 0.0906 | 0.1798 | 0.1387 | 0.1575 | 0.1280 | 0.1189 | 0.1505 | 0.1218 | 0.3898 | 0.1545 | 0.0012 | 0.0034 | 0.0079 | 0.0230 | 0.0477 | 0.0880 | 0.0938 | 0.1052 | 0.6296 | 16 | 19 | 22 | 26 | 40 | 80 | 154 | 256 | 424 | 0.0499 | 24.57 | 5.020 | 0.5076 | 59283.3 | 35800000 | 26400000000 | 22500000000000 | 0.6077 | 0.0916 | 0.0465 | 0.0024 | 0.1573 | 0.0221 | 0.2370 | 0.0945 | 0.1899 | 0.1299 | 0.1567 | 0.1853 | 0.1107 | 0.1877 | 0.0559 | 0.1296 | 0.0288 | 0.1216 | 0.0172 | 0.1270 | 0.0004 | 0.0003 | 0.0007 | 0.0014 | 0.0025 | 0.0019 | 0.0149 | 0.0139 | 0.0556 | 0.0499 | 0.0753 | 0.0693 | 0.0592 | 0.0511 | 0.0899 | 0.0801 | 0.7015 | 0.7321 | 0.0005 | 0.0015 | 0.0016 | 0.0014 | 0.0046 | 0.0059 | 0.0219 | 0.0234 | 0.0658 | 0.0751 | 0.1028 | 0.1190 | 0.0811 | 0.0870 | 0.1118 | 0.1202 | 0.6099 | 0.5665 | 0.0007 | 0.0013 | 0.0027 | 0.0190 | 0.0556 | 0.0905 | 0.0669 | 0.0992 | 0.6642 |
| Hs 578T | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 1199 | 269 | | 6858 | 34380 | 182.5 | 52.85 | 124.86 | 199.10 | 122 | 141 | 154 | 165 | 177 | 190 | 204 | 222 | 256 | 0.0332 | 1142 | 0.787 | 31.00 | 8.06 | 3 | 0.0117 | 80 | 0.0011 | 37.84 | 7.176 | 0.1947 | 36107.4 | 7670000 | 1740000000 | 418000000000 | 0.4164 | 0.2188 | 0.0008 | 0.0000 | 0.0016 | 0.0003 | 0.0074 | 0.0003 | 0.0251 | 0.0031 | 0.0740 | 0.0238 | 0.1294 | 0.0417 | 0.1524 | 0.0466 | 0.1762 | 0.0732 | 0.4332 | 0.8108 | 0.0004 | 0.0000 | 0.0004 | 0.0000 | 0.0034 | 0.0000 | 0.0103 | 0.0012 | 0.0321 | 0.0128 | 0.0530 | 0.0208 | 0.0614 | 0.0187 | 0.0821 | 0.0317 | 0.7569 | 0.9147 | 0.0035 | 0.0089 | 0.0090 | 0.0089 | 0.0097 | 0.0222 | 0.0520 | 0.0532 | 0.0929 | 0.1064 | 0.1283 | 0.1241 | 0.0999 | 0.1004 | 0.1200 | 0.1241 | 0.4847 | 0.4520 | 0.0016 | 0.0038 | 0.0074 | 0.0272 | 0.0579 | 0.0886 | 0.0908 | 0.1164 | 0.6063 | 17 | 21 | 25 | 29 | 35 | 48 | 91 | 194 | 364 | 0.0577 | 29.38 | 4.737 | 0.5383 | 55230.0 | 41200000 | 40500000000 | 47700000000000 | 0.3925 | 0.2378 | 0.1380 | 0.0050 | 0.3601 | 0.0465 | 0.2981 | 0.2724 | 0.1080 | 0.2297 | 0.0587 | 0.1914 | 0.0244 | 0.1219 | 0.0089 | 0.0649 | 0.0028 | 0.0419 | 0.0011 | 0.0263 | 0.0001 | 0.0001 | 0.0004 | 0.0005 | 0.0019 | 0.0020 | 0.0186 | 0.0147 | 0.0758 | 0.0670 | 0.1162 | 0.0990 | 0.0798 | 0.0694 | 0.1195 | 0.1071 | 0.5878 | 0.6402 | 0.0002 | 0.0003 | 0.0007 | 0.0022 | 0.0033 | 0.0056 | 0.0256 | 0.0302 | 0.0905 | 0.0964 | 0.1439 | 0.1483 | 0.0934 | 0.1014 | 0.1314 | 0.1378 | 0.5108 | 0.4778 | 0.0002 | 0.0007 | 0.0022 | 0.0238 | 0.0786 | 0.1331 | 0.0854 | 0.1281 | 0.5480 |
| Hs 578T | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 487 | 388 | | 17803 | 45389 | 157.0 | 50.28 | 154.36 | 177.24 | 92 | 114 | 128 | 142 | 155 | 168 | 183 | 200 | 225 | 0.0425 | 1928 | 1.251 | 24.52 | 7.81 | 5 | 0.0033 | 58 | 0.0011 | 27.12 | 7.140 | 0.2383 | 27189.4 | 5090000 | 1010000000 | 213000000000 | 0.4282 | 0.2106 | 0.0016 | 0.0001 | 0.0027 | 0.0011 | 0.0080 | 0.0022 | 0.0288 | 0.0083 | 0.0923 | 0.0292 | 0.1552 | 0.0530 | 0.1536 | 0.0615 | 0.1813 | 0.0892 | 0.3764 | 0.7554 | 0.0006 | 0.0001 | 0.0008 | 0.0008 | 0.0020 | 0.0012 | 0.0062 | 0.0038 | 0.0238 | 0.0118 | 0.0466 | 0.0193 | 0.0520 | 0.0202 | 0.0673 | 0.0299 | 0.8006 | 0.9130 | 0.0028 | 0.0076 | 0.0051 | 0.0076 | 0.0145 | 0.0286 | 0.0373 | 0.0753 | 0.0821 | 0.1201 | 0.1345 | 0.1711 | 0.1117 | 0.1287 | 0.1381 | 0.1368 | 0.4740 | 0.3241 | 0.0009 | 0.0019 | 0.0057 | 0.0186 | 0.0505 | 0.0897 | 0.0859 | 0.1121 | 0.6346 | 13 | 18 | 26 | 47 | 81 | 128 | 193 | 278 | 407 | 0.0395 | 20.75 | 5.394 | 0.5005 | 55240.7 | 27700000 | 16900000000 | 11900000000000 | 0.4247 | 0.2143 | 0.0378 | 0.0014 | 0.1492 | 0.0110 | 0.2622 | 0.0683 | 0.1893 | 0.1171 | 0.1504 | 0.1913 | 0.1095 | 0.1978 | 0.0586 | 0.1383 | 0.0341 | 0.1296 | 0.0088 | 0.1451 | 0.0003 | 0.0002 | 0.0011 | 0.0008 | 0.0022 | 0.0018 | 0.0130 | 0.0095 | 0.0518 | 0.0406 | 0.0919 | 0.0720 | 0.0661 | 0.0535 | 0.0987 | 0.0822 | 0.6750 | 0.7394 | 0.0006 | 0.0006 | 0.0012 | 0.0024 | 0.0051 | 0.0080 | 0.0184 | 0.0254 | 0.0735 | 0.0834 | 0.1248 | 0.1314 | 0.0862 | 0.0949 | 0.1190 | 0.1284 | 0.5712 | 0.5254 | 0.0004 | 0.0015 | 0.0030 | 0.0169 | 0.0596 | 0.1071 | 0.0813 | 0.1092 | 0.6210 |
| Hs 578T | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 798 | 428 | | 27432 | 45118 | 211.1 | 59.97 | 98.82 | 173.21 | 140 | 162 | 179 | 194 | 208 | 223 | 239 | 258 | 287 | 0.0427 | 1927 | 0.804 | 104.04 | 21.19 | 1 | 0.0082 | 226 | 0.0007 | 43.54 | 7.545 | 0.1862 | 48158.5 | 11800000 | 3050000000 | 838000000000 | 0.4170 | 0.2298 | 0.0009 | 0.0000 | 0.0014 | 0.0001 | 0.0072 | 0.0005 | 0.0254 | 0.0026 | 0.0661 | 0.0188 | 0.1224 | 0.0410 | 0.1361 | 0.0439 | 0.1737 | 0.0674 | 0.4667 | 0.8259 | 0.0003 | 0.0000 | 0.0006 | 0.0000 | 0.0027 | 0.0001 | 0.0072 | 0.0009 | 0.0239 | 0.0093 | 0.0448 | 0.0189 | 0.0494 | 0.0177 | 0.0650 | 0.0292 | 0.8061 | 0.9239 | 0.0049 | 0.0049 | 0.0082 | 0.0175 | 0.0196 | 0.0265 | 0.0469 | 0.0746 | 0.0894 | 0.1169 | 0.1266 | 0.1677 | 0.1090 | 0.1102 | 0.1271 | 0.1250 | 0.4683 | 0.3566 | 0.0014 | 0.0023 | 0.0066 | 0.0227 | 0.0535 | 0.0917 | 0.0877 | 0.1135 | 0.6206 | 10 | 12 | 14 | 16 | 20 | 29 | 54 | 137 | 332 | 0.1819 | 23.17 | 3.891 | 0.6587 | 39767.1 | 24100000 | 17400000000 | 14100000000000 | 0.4082 | 0.2647 | 0.1462 | 0.0039 | 0.3078 | 0.0465 | 0.2795 | 0.2378 | 0.1040 | 0.2151 | 0.0818 | 0.2042 | 0.0463 | 0.1441 | 0.0206 | 0.0647 | 0.0093 | 0.0494 | 0.0046 | 0.0343 | 0.0000 | 0.0000 | 0.0009 | 0.0006 | 0.0015 | 0.0011 | 0.0142 | 0.0095 | 0.0704 | 0.0604 | 0.0987 | 0.0930 | 0.0678 | 0.0551 | 0.1104 | 0.0943 | 0.6360 | 0.6860 | 0.0003 | 0.0000 | 0.0017 | 0.0017 | 0.0033 | 0.0043 | 0.0185 | 0.0216 | 0.0848 | 0.0897 | 0.1211 | 0.1251 | 0.0804 | 0.0863 | 0.1188 | 0.1212 | 0.5710 | 0.5502 | 0.0001 | 0.0006 | 0.0030 | 0.0167 | 0.0751 | 0.1185 | 0.0740 | 0.1117 | 0.6002 |
| Hs 578T | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 1123 | 430 | | 9439 | 30387 | 187.6 | 49.18 | 85.43 | 137.20 | 127 | 150 | 163 | 176 | 187 | 199 | 211 | 226 | 249 | 0.0448 | 1360 | 0.978 | 133.06 | 44.05 | 3 | 0.0366 | 345 | 0.0011 | 36.27 | 7.174 | 0.1963 | 37625.0 | 7970000 | 1770000000 | 413000000000 | 0.4260 | 0.2189 | 0.0002 | 0.0000 | 0.0009 | 0.0001 | 0.0043 | 0.0007 | 0.0199 | 0.0027 | 0.0634 | 0.0169 | 0.1233 | 0.0399 | 0.1423 | 0.0401 | 0.1734 | 0.0580 | 0.4723 | 0.8415 | 0.0000 | 0.0000 | 0.0007 | 0.0000 | 0.0016 | 0.0000 | 0.0072 | 0.0010 | 0.0225 | 0.0102 | 0.0434 | 0.0235 | 0.0516 | 0.0149 | 0.0628 | 0.0250 | 0.8102 | 0.9254 | 0.0063 | 0.0066 | 0.0083 | 0.0115 | 0.0276 | 0.0508 | 0.0683 | 0.0869 | 0.1017 | 0.1328 | 0.1424 | 0.1410 | 0.1226 | 0.1016 | 0.1346 | 0.1279 | 0.3881 | 0.3410 | 0.0009 | 0.0032 | 0.0071 | 0.0234 | 0.0626 | 0.0939 | 0.0934 | 0.1316 | 0.5841 | 10 | 12 | 14 | 16 | 20 | 29 | 62 | 140 | 267 | 0.1579 | 16.30 | 3.924 | 0.6407 | 26120.0 | 12600000 | 7750000000 | 5660000000000 | 0.5727 | 0.1271 | 0.1171 | 0.0076 | 0.2705 | 0.0420 | 0.2342 | 0.2186 | 0.1164 | 0.1757 | 0.1023 | 0.1567 | 0.0686 | 0.1384 | 0.0444 | 0.0856 | 0.0316 | 0.0752 | 0.0148 | 0.1002 | 0.0003 | 0.0005 | 0.0015 | 0.0008 | 0.0032 | 0.0031 | 0.0147 | 0.0133 | 0.0655 | 0.0528 | 0.0960 | 0.0906 | 0.0648 | 0.0549 | 0.0997 | 0.0876 | 0.6543 | 0.6964 | 0.0001 | 0.0004 | 0.0007 | 0.0004 | 0.0029 | 0.0039 | 0.0241 | 0.0258 | 0.0759 | 0.0823 | 0.1193 | 0.1295 | 0.0787 | 0.0827 | 0.1092 | 0.1138 | 0.5892 | 0.5612 | 0.0004 | 0.0010 | 0.0023 | 0.0194 | 0.0694 | 0.1084 | 0.0725 | 0.1053 | 0.6214 |
| Hs 578T | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 224 | 664 | | 23929 | 53243 | 235.7 | 71.53 | 198.53 | 308.24 | 140 | 172 | 197 | 217 | 235 | 254 | 274 | 298 | 328 | 0.0344 | 1829 | 0.641 | 165.59 | 39.45 | 7 | 0.0212 | 508 | 0.0005 | 51.67 | 7.813 | 0.1685 | 60653.4 | 16700000 | 4890000000 | 1500000000000 | 0.4168 | 0.2169 | 0.0013 | 0.0002 | 0.0025 | 0.0005 | 0.0085 | 0.0016 | 0.0313 | 0.0057 | 0.0797 | 0.0252 | 0.1433 | 0.0530 | 0.1429 | 0.0600 | 0.1764 | 0.0821 | 0.4142 | 0.7718 | 0.0006 | 0.0002 | 0.0010 | 0.0003 | 0.0020 | 0.0007 | 0.0074 | 0.0028 | 0.0227 | 0.0123 | 0.0429 | 0.0258 | 0.0415 | 0.0237 | 0.0600 | 0.0321 | 0.8218 | 0.9020 | 0.0018 | 0.0071 | 0.0045 | 0.0102 | 0.0154 | 0.0252 | 0.0432 | 0.0885 | 0.0873 | 0.1322 | 0.1280 | 0.1588 | 0.1107 | 0.1225 | 0.1340 | 0.1433 | 0.4752 | 0.3123 | 0.0008 | 0.0021 | 0.0061 | 0.0159 | 0.0445 | 0.0832 | 0.0794 | 0.1112 | 0.6569 | 15 | 19 | 23 | 31 | 50 | 98 | 191 | 331 | 581 | 0.0417 | 56.38 | 5.497 | 0.4839 | 134424.0 | 143000000 | 193000000000 | 306000000000000 | 0.3773 | 0.2809 | 0.0950 | 0.0031 | 0.2742 | 0.0340 | 0.2930 | 0.1903 | 0.1326 | 0.1923 | 0.0925 | 0.1954 | 0.0613 | 0.1542 | 0.0320 | 0.0969 | 0.0146 | 0.0718 | 0.0047 | 0.0620 | 0.0002 | 0.0002 | 0.0007 | 0.0005 | 0.0028 | 0.0019 | 0.0151 | 0.0118 | 0.0675 | 0.0598 | 0.1124 | 0.0965 | 0.0779 | 0.0655 | 0.1108 | 0.0997 | 0.6126 | 0.6642 | 0.0005 | 0.0011 | 0.0017 | 0.0024 | 0.0055 | 0.0069 | 0.0244 | 0.0283 | 0.0804 | 0.0894 | 0.1332 | 0.1361 | 0.0938 | 0.0992 | 0.1210 | 0.1267 | 0.5395 | 0.5097 | 0.0004 | 0.0016 | 0.0031 | 0.0214 | 0.0760 | 0.1177 | 0.0887 | 0.1187 | 0.5725 |
| Hs 578T | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 960 | 785 | | 14324 | 30146 | 220.1 | 48.30 | 124.97 | 184.42 | 157 | 180 | 197 | 210 | 222 | 234 | 246 | 262 | 280 | 0.0506 | 1525 | 1.218 | 105.55 | 39.82 | 5 | 0.0186 | 266 | 0.0010 | 36.62 | 7.236 | 0.1928 | 50767.5 | 12200000 | 3020000000 | 771000000000 | 0.3776 | 0.2614 | 0.0006 | 0.0000 | 0.0007 | 0.0000 | 0.0054 | 0.0001 | 0.0194 | 0.0010 | 0.0554 | 0.0114 | 0.1099 | 0.0262 | 0.1289 | 0.0281 | 0.1632 | 0.0425 | 0.5166 | 0.8907 | 0.0003 | 0.0000 | 0.0001 | 0.0000 | 0.0019 | 0.0000 | 0.0064 | 0.0003 | 0.0181 | 0.0084 | 0.0357 | 0.0167 | 0.0450 | 0.0127 | 0.0607 | 0.0189 | 0.8318 | 0.9430 | 0.0040 | 0.0182 | 0.0081 | 0.0286 | 0.0316 | 0.0909 | 0.0683 | 0.1506 | 0.1278 | 0.2052 | 0.1725 | 0.1740 | 0.1366 | 0.1117 | 0.1490 | 0.1039 | 0.3021 | 0.1169 | 0.0009 | 0.0031 | 0.0069 | 0.0208 | 0.0550 | 0.0930 | 0.1034 | 0.1315 | 0.5854 | 12 | 15 | 19 | 26 | 43 | 72 | 121 | 198 | 355 | 0.0673 | 18.66 | 4.787 | 0.5693 | 49625.5 | 32400000 | 28000000000 | 29100000000000 | 0.5089 | 0.1429 | 0.0634 | 0.0024 | 0.1947 | 0.0244 | 0.2245 | 0.1272 | 0.1694 | 0.1268 | 0.1346 | 0.1704 | 0.0969 | 0.1796 | 0.0580 | 0.1221 | 0.0414 | 0.1040 | 0.0170 | 0.1433 | 0.0006 | 0.0003 | 0.0017 | 0.0012 | 0.0033 | 0.0024 | 0.0152 | 0.0164 | 0.0709 | 0.0583 | 0.1015 | 0.0909 | 0.0701 | 0.0625 | 0.1026 | 0.0863 | 0.6341 | 0.6818 | 0.0001 | 0.0007 | 0.0023 | 0.0034 | 0.0068 | 0.0081 | 0.0275 | 0.0324 | 0.0863 | 0.0889 | 0.1257 | 0.1296 | 0.0840 | 0.0940 | 0.1076 | 0.1098 | 0.5596 | 0.5331 | 0.0005 | 0.0014 | 0.0043 | 0.0212 | 0.0766 | 0.1127 | 0.0825 | 0.1069 | 0.5940 |
| Hs 578T | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 666 | 842 | | 12884 | 27221 | 219.0 | 58.92 | 118.73 | 205.47 | 152 | 171 | 185 | 199 | 212 | 227 | 245 | 268 | 298 | 0.0499 | 1359 | 0.808 | 193.62 | 44.05 | 2 | 0.0354 | 456 | 0.0008 | 46.64 | 7.460 | 0.1768 | 51441.8 | 12900000 | 3430000000 | 964000000000 | 0.4180 | 0.2281 | 0.0003 | 0.0001 | 0.0020 | 0.0000 | 0.0075 | 0.0004 | 0.0271 | 0.0027 | 0.0783 | 0.0206 | 0.1403 | 0.0412 | 0.1412 | 0.0459 | 0.1709 | 0.0684 | 0.4325 | 0.8207 | 0.0001 | 0.0000 | 0.0013 | 0.0000 | 0.0023 | 0.0000 | 0.0103 | 0.0014 | 0.0303 | 0.0115 | 0.0505 | 0.0181 | 0.0596 | 0.0180 | 0.0775 | 0.0275 | 0.7681 | 0.9236 | 0.0028 | 0.0068 | 0.0028 | 0.0184 | 0.0137 | 0.0261 | 0.0439 | 0.0812 | 0.0847 | 0.1285 | 0.1612 | 0.1865 | 0.1135 | 0.0889 | 0.1377 | 0.1449 | 0.4398 | 0.3188 | 0.0017 | 0.0044 | 0.0094 | 0.0269 | 0.0584 | 0.0906 | 0.0952 | 0.1178 | 0.5957 | 12 | 14 | 16 | 19 | 23 | 35 | 81 | 186 | 369 | 0.1090 | 28.98 | 4.298 | 0.6029 | 56311.6 | 43400000 | 43600000000 | 52400000000000 | 0.4887 | 0.1540 | 0.1380 | 0.0057 | 0.3027 | 0.0505 | 0.2534 | 0.2149 | 0.1170 | 0.1937 | 0.0888 | 0.2013 | 0.0605 | 0.1398 | 0.0282 | 0.0765 | 0.0105 | 0.0629 | 0.0008 | 0.0547 | 0.0000 | 0.0004 | 0.0018 | 0.0008 | 0.0016 | 0.0015 | 0.0149 | 0.0108 | 0.0607 | 0.0575 | 0.0912 | 0.0799 | 0.0683 | 0.0568 | 0.1015 | 0.0892 | 0.6600 | 0.7031 | 0.0005 | 0.0000 | 0.0008 | 0.0012 | 0.0040 | 0.0058 | 0.0208 | 0.0226 | 0.0784 | 0.0804 | 0.1103 | 0.1258 | 0.0842 | 0.0911 | 0.1132 | 0.1227 | 0.5879 | 0.5503 | 0.0004 | 0.0011 | 0.0027 | 0.0160 | 0.0680 | 0.1060 | 0.0721 | 0.1158 | 0.6178 |
| Hs 578T | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 1142 | 857 | | 7401 | 14616 | 171.0 | 66.26 | 71.29 | 133.72 | 97 | 113 | 126 | 141 | 159 | 177 | 198 | 227 | 267 | 0.0757 | 1106 | 0.455 | 200.25 | 41.00 | 7 | 0.0947 | 701 | 0.0014 | 22.02 | 6.984 | 0.2885 | 33621.9 | 7480000 | 1840000000 | 492000000000 | 0.3427 | 0.2805 | 0.0023 | 0.0008 | 0.0023 | 0.0025 | 0.0164 | 0.0059 | 0.0279 | 0.0086 | 0.0707 | 0.0301 | 0.1250 | 0.0604 | 0.1170 | 0.0539 | 0.1514 | 0.0722 | 0.4868 | 0.7658 | 0.0004 | 0.0005 | 0.0013 | 0.0012 | 0.0054 | 0.0022 | 0.0073 | 0.0043 | 0.0207 | 0.0130 | 0.0326 | 0.0254 | 0.0318 | 0.0221 | 0.0443 | 0.0300 | 0.8561 | 0.9014 | 0.0010 | 0.0000 | 0.0030 | 0.0041 | 0.0094 | 0.0058 | 0.0189 | 0.0386 | 0.0506 | 0.0641 | 0.0839 | 0.1191 | 0.0645 | 0.0994 | 0.0948 | 0.1224 | 0.6738 | 0.5464 | 0.0012 | 0.0025 | 0.0065 | 0.0109 | 0.0349 | 0.0477 | 0.0514 | 0.0767 | 0.7681 | 10 | 12 | 14 | 16 | 20 | 33 | 59 | 100 | 185 | 0.1556 | 7.37 | 3.609 | 0.6941 | 22963.2 | 18300000 | 21700000000 | 29800000000000 | 0.5623 | 0.1121 | 0.0192 | 0.0013 | 0.1028 | 0.0217 | 0.1742 | 0.0579 | 0.2030 | 0.0744 | 0.1838 | 0.1431 | 0.1324 | 0.1783 | 0.0941 | 0.1601 | 0.0662 | 0.1353 | 0.0244 | 0.2279 | 0.0000 | 0.0002 | 0.0020 | 0.0025 | 0.0051 | 0.0046 | 0.0151 | 0.0122 | 0.0523 | 0.0408 | 0.0785 | 0.0615 | 0.0621 | 0.0522 | 0.0923 | 0.0762 | 0.6926 | 0.7500 | 0.0006 | 0.0003 | 0.0012 | 0.0037 | 0.0062 | 0.0075 | 0.0211 | 0.0251 | 0.0699 | 0.0728 | 0.1077 | 0.1162 | 0.0759 | 0.0799 | 0.1107 | 0.1118 | 0.6067 | 0.5827 | 0.0003 | 0.0008 | 0.0031 | 0.0230 | 0.0637 | 0.0872 | 0.0730 | 0.0993 | 0.6497 |
| Hs 578T | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 323 | 867 | | 400 | 2994 | 116.9 | 58.63 | 22.33 | 36.51 | 37 | 54 | 72 | 93 | 117 | 142 | 160 | 180 | 198 | 0.1226 | 367 | 0.942 | 240.52 | 72.24 | 1 | 1.5125 | 605 | 0.0035 | 23.39 | 5.736 | 0.2403 | 17090.1 | 2810000 | 490000000 | 88800000000 | 0.2385 | 0.3935 | 0.0000 | 0.0000 | 0.0513 | 0.0000 | 0.1795 | 0.0000 | 0.1538 | 0.0058 | 0.1667 | 0.1503 | 0.3333 | 0.3006 | 0.0897 | 0.1214 | 0.0256 | 0.1676 | 0.0000 | 0.2543 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0126 | 0.0035 | 0.0544 | 0.0632 | 0.1088 | 0.0912 | 0.0502 | 0.0421 | 0.0711 | 0.0807 | 0.7029 | 0.7193 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0124 | 0.0268 | 0.0745 | 0.0893 | 0.1491 | 0.1518 | 0.0497 | 0.0893 | 0.0745 | 0.0714 | 0.6398 | 0.5714 | 0.0000 | 0.0000 | 0.0000 | 0.0100 | 0.0650 | 0.1250 | 0.0450 | 0.0850 | 0.6700 | 10 | 12 | 13 | 14 | 15 | 16 | 17 | 19 | 23 | 0.4250 | 1.44 | 1.571 | 0.8267 | 1831.5 | 395412 | 109000000 | 33000000000 | 0.4696 | 0.1619 | 0.1029 | 0.0135 | 0.1942 | 0.0486 | 0.2233 | 0.0774 | 0.1786 | 0.1014 | 0.1553 | 0.1463 | 0.0932 | 0.1635 | 0.0447 | 0.1825 | 0.0078 | 0.1530 | 0.0000 | 0.1137 | 0.0663 | 0.0119 | 0.1183 | 0.0404 | 0.1222 | 0.0652 | 0.0923 | 0.0836 | 0.1105 | 0.1218 | 0.0923 | 0.1358 | 0.0715 | 0.1547 | 0.0871 | 0.1574 | 0.2393 | 0.2291 | 0.0000 | 0.0000 | 0.0000 | 0.0044 | 0.0236 | 0.0175 | 0.0669 | 0.0658 | 0.1024 | 0.1491 | 0.1614 | 0.1184 | 0.1024 | 0.1009 | 0.1102 | 0.1272 | 0.4331 | 0.4167 | 0.0845 | 0.0310 | 0.0338 | 0.0451 | 0.1070 | 0.1070 | 0.1014 | 0.0986 | 0.3915 |
| Hs 578T | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 369 | 897 | | 508 | 2542 | 168.7 | 101.76 | 78.27 | 159.27 | 36 | 52 | 79 | 122 | 170 | 212 | 254 | 284 | 304 | 0.1326 | 337 | 0.963 | 124.46 | 46.23 | 1 | 0.6909 | 351 | 0.0029 | 78.06 | 5.974 | 0.1808 | 38792.0 | 10100000 | 2760000000 | 778000000000 | 0.2699 | 0.3263 | 0.0000 | 0.0000 | 0.0278 | 0.0000 | 0.2917 | 0.0000 | 0.3889 | 0.0065 | 0.1528 | 0.1883 | 0.0556 | 0.3701 | 0.0556 | 0.2013 | 0.0278 | 0.0909 | 0.0000 | 0.1429 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0104 | 0.0000 | 0.0519 | 0.0604 | 0.0900 | 0.0876 | 0.0484 | 0.0363 | 0.0727 | 0.0695 | 0.7266 | 0.7462 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0092 | 0.0113 | 0.0553 | 0.0791 | 0.1244 | 0.1017 | 0.0369 | 0.0508 | 0.0691 | 0.0904 | 0.7051 | 0.6667 | 0.0000 | 0.0000 | 0.0039 | 0.0039 | 0.0547 | 0.1094 | 0.0352 | 0.0742 | 0.7188 | 14 | 16 | 18 | 20 | 22 | 28 | 42 | 75 | 198 | 0.0967 | 17.71 | 3.564 | 0.6230 | 31483.0 | 24000000 | 22900000000 | 24100000000000 | 0.5318 | 0.1158 | 0.1119 | 0.0000 | 0.3731 | 0.0552 | 0.2836 | 0.1595 | 0.0970 | 0.2209 | 0.0672 | 0.2331 | 0.0299 | 0.1626 | 0.0299 | 0.0890 | 0.0075 | 0.0491 | 0.0000 | 0.0307 | 0.0000 | 0.0000 | 0.0035 | 0.0014 | 0.0086 | 0.0043 | 0.0276 | 0.0340 | 0.1261 | 0.1007 | 0.1572 | 0.1277 | 0.0950 | 0.0879 | 0.1295 | 0.1433 | 0.4525 | 0.5007 | 0.0000 | 0.0026 | 0.0112 | 0.0026 | 0.0067 | 0.0211 | 0.0315 | 0.0554 | 0.1393 | 0.1135 | 0.1685 | 0.1821 | 0.0921 | 0.1055 | 0.1573 | 0.1293 | 0.3933 | 0.3879 | 0.0000 | 0.0040 | 0.0140 | 0.0460 | 0.1180 | 0.1560 | 0.0960 | 0.1540 | 0.4120 |
| Hs 578T | Barasertib | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 15 | 1 | 702 | 223 | | 941 | 12390 | 79.6 | 29.54 | 182.48 | 238.48 | 36 | 53 | 62 | 72 | 81 | 87 | 96 | 106 | 120 | 0.0553 | 685 | 0.420 | 238.65 | 45.22 | 1 | 0.8013 | 754 | 0.0030 | 21.04 | 6.013 | 0.2638 | 7208.4 | 713221 | 75200000 | 8310000000 | 0.4207 | 0.1971 | 0.0028 | 0.0000 | 0.0140 | 0.0000 | 0.0955 | 0.0016 | 0.1124 | 0.0078 | 0.1376 | 0.0889 | 0.1713 | 0.1404 | 0.1292 | 0.1420 | 0.1573 | 0.1451 | 0.1798 | 0.4743 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0015 | 0.0000 | 0.0077 | 0.0025 | 0.0526 | 0.0406 | 0.0896 | 0.0570 | 0.0526 | 0.0456 | 0.0881 | 0.0646 | 0.7079 | 0.7896 | 0.0000 | 0.0068 | 0.0069 | 0.0000 | 0.0309 | 0.0270 | 0.0378 | 0.1216 | 0.1478 | 0.2027 | 0.1890 | 0.2027 | 0.1168 | 0.1757 | 0.1787 | 0.1622 | 0.2921 | 0.1014 | 0.0000 | 0.0020 | 0.0041 | 0.0244 | 0.0815 | 0.1120 | 0.1303 | 0.1589 | 0.4868 | 13 | 16 | 20 | 30 | 62 | 129 | 225 | 349 | 522 | 0.0743 | 27.27 | 5.116 | 0.5188 | 90166.0 | 64100000 | 58300000000 | 64100000000000 | 0.4933 | 0.1833 | 0.0624 | 0.0027 | 0.1895 | 0.0226 | 0.2793 | 0.1183 | 0.1763 | 0.1656 | 0.1490 | 0.2005 | 0.0876 | 0.1919 | 0.0394 | 0.1156 | 0.0153 | 0.1102 | 0.0011 | 0.0726 | 0.0004 | 0.0002 | 0.0023 | 0.0013 | 0.0047 | 0.0036 | 0.0157 | 0.0126 | 0.0591 | 0.0491 | 0.0882 | 0.0803 | 0.0608 | 0.0573 | 0.0914 | 0.0794 | 0.6774 | 0.7162 | 0.0005 | 0.0015 | 0.0024 | 0.0015 | 0.0061 | 0.0041 | 0.0198 | 0.0215 | 0.0614 | 0.0684 | 0.1002 | 0.1256 | 0.0833 | 0.0902 | 0.1091 | 0.1368 | 0.6172 | 0.5505 | 0.0019 | 0.0029 | 0.0038 | 0.0150 | 0.0588 | 0.0954 | 0.0711 | 0.1004 | 0.6507 |
| Hs 578T | Barasertib | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 15 | 1 | 903 | 431 | | 54613 | 82874 | 84.8 | 46.65 | 114.00 | 205.41 | 23 | 28 | 54 | 73 | 87 | 99 | 112 | 126 | 146 | 0.0303 | 2514 | 0.607 | 231.82 | 52.47 | 24 | 0.0118 | 645 | 0.0046 | 13.65 | 6.351 | 0.3627 | 9367.0 | 1190000 | 165000000 | 24700000000 | 0.5125 | 0.1476 | 0.0017 | 0.0007 | 0.0076 | 0.0010 | 0.0380 | 0.0040 | 0.0801 | 0.0150 | 0.1435 | 0.0575 | 0.1828 | 0.1084 | 0.1675 | 0.1062 | 0.1626 | 0.1362 | 0.2163 | 0.5709 | 0.0002 | 0.0000 | 0.0004 | 0.0000 | 0.0014 | 0.0002 | 0.0055 | 0.0015 | 0.0213 | 0.0119 | 0.0388 | 0.0234 | 0.0374 | 0.0198 | 0.0551 | 0.0316 | 0.8399 | 0.9117 | 0.0006 | 0.0018 | 0.0028 | 0.0048 | 0.0065 | 0.0130 | 0.0229 | 0.0391 | 0.0576 | 0.0808 | 0.0882 | 0.1189 | 0.0857 | 0.0985 | 0.1117 | 0.1228 | 0.6241 | 0.5203 | 0.0004 | 0.0014 | 0.0040 | 0.0124 | 0.0339 | 0.0605 | 0.0589 | 0.0824 | 0.7461 | 10 | 12 | 13 | 15 | 18 | 26 | 61 | 174 | 383 | 0.2390 | 19.16 | 3.787 | 0.6638 | 55186.4 | 40400000 | 36400000000 | 37700000000000 | 0.4605 | 0.1949 | 0.1576 | 0.0035 | 0.3814 | 0.0611 | 0.3071 | 0.3277 | 0.0839 | 0.2234 | 0.0408 | 0.1726 | 0.0158 | 0.1086 | 0.0071 | 0.0487 | 0.0039 | 0.0298 | 0.0026 | 0.0245 | 0.0001 | 0.0001 | 0.0006 | 0.0003 | 0.0013 | 0.0008 | 0.0117 | 0.0106 | 0.0652 | 0.0602 | 0.1027 | 0.0939 | 0.0640 | 0.0575 | 0.0983 | 0.0881 | 0.6561 | 0.6885 | 0.0000 | 0.0004 | 0.0009 | 0.0009 | 0.0020 | 0.0025 | 0.0164 | 0.0184 | 0.0742 | 0.0778 | 0.1173 | 0.1225 | 0.0764 | 0.0817 | 0.1085 | 0.1098 | 0.6044 | 0.5860 | 0.0001 | 0.0002 | 0.0017 | 0.0132 | 0.0722 | 0.1105 | 0.0693 | 0.1056 | 0.6272 |
| Hs 578T | Barasertib | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 15 | 1 | 79 | 365 | | 355 | 368 | 98.5 | 34.30 | 743.33 | 441.89 | 53 | 66 | 81 | 90 | 95 | 105 | 117 | 132 | 143 | 0.3995 | 147 | 1.183 | 36.12 | 15.52 | 1 | 0.2817 | 100 | 0.0040 | 43.26 | 5.614 | 0.2000 | 10879.1 | 1310000 | 169000000 | 22900000000 | 0.3710 | 0.2410 | 0.0000 | 0.0000 | 0.0265 | 0.0000 | 0.1060 | 0.0041 | 0.0927 | 0.0122 | 0.1258 | 0.1306 | 0.2053 | 0.1796 | 0.1589 | 0.1469 | 0.1126 | 0.1429 | 0.1722 | 0.3837 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0040 | 0.0000 | 0.0159 | 0.0067 | 0.0556 | 0.0669 | 0.1032 | 0.0635 | 0.0635 | 0.0535 | 0.1111 | 0.0702 | 0.6468 | 0.7391 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0297 | 0.1111 | 0.0792 | 0.2037 | 0.1386 | 0.2037 | 0.2673 | 0.2037 | 0.1287 | 0.1296 | 0.1287 | 0.1111 | 0.2277 | 0.0370 | 0.0000 | 0.0060 | 0.0060 | 0.0539 | 0.1257 | 0.1796 | 0.0958 | 0.1796 | 0.3533 | 167 | 338 | 432 | 575 | 717 | 837 | 975 | 1120 | 1332 | 0.0029 | 177.01 | 5.867 | 0.1008 | 747281.0 | 884000000 | 1170000000000 | 1.66E+15 | 0.3788 | 0.2356 | 0.0116 | 0.0127 | 0.1744 | 0.0570 | 0.2209 | 0.0633 | 0.2326 | 0.1266 | 0.1512 | 0.2089 | 0.1279 | 0.1835 | 0.0814 | 0.1835 | 0.0000 | 0.0886 | 0.0000 | 0.0759 | 0.0000 | 0.0040 | 0.0230 | 0.0199 | 0.0230 | 0.0199 | 0.0829 | 0.0598 | 0.1429 | 0.1474 | 0.1060 | 0.1235 | 0.1567 | 0.1474 | 0.1751 | 0.1633 | 0.2903 | 0.3147 | 0.0000 | 0.0000 | 0.0076 | 0.0108 | 0.0458 | 0.0323 | 0.0458 | 0.0860 | 0.2061 | 0.2688 | 0.1756 | 0.2151 | 0.1374 | 0.1720 | 0.2443 | 0.1828 | 0.1374 | 0.0323 | 0.0058 | 0.0173 | 0.0405 | 0.0578 | 0.1214 | 0.1445 | 0.1792 | 0.1850 | 0.2486 |
| Hs 578T | Barasertib | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 15 | 1 | 207 | 478 | | 13048 | 26519 | 97.0 | 27.99 | 161.98 | 234.77 | 64 | 74 | 81 | 88 | 95 | 102 | 109 | 119 | 134 | 0.0514 | 1363 | 0.414 | 318.40 | 44.82 | 2 | 0.0676 | 882 | 0.0022 | 19.38 | 6.429 | 0.2488 | 10191.1 | 1150000 | 139000000 | 17800000000 | 0.4486 | 0.1898 | 0.0006 | 0.0001 | 0.0026 | 0.0001 | 0.0142 | 0.0005 | 0.0573 | 0.0057 | 0.1294 | 0.0245 | 0.1873 | 0.0596 | 0.1931 | 0.0819 | 0.1988 | 0.1265 | 0.2168 | 0.7010 | 0.0000 | 0.0000 | 0.0002 | 0.0000 | 0.0021 | 0.0002 | 0.0123 | 0.0021 | 0.0425 | 0.0125 | 0.0796 | 0.0275 | 0.0907 | 0.0335 | 0.1311 | 0.0529 | 0.6415 | 0.8713 | 0.0086 | 0.0180 | 0.0124 | 0.0237 | 0.0341 | 0.0606 | 0.0834 | 0.1219 | 0.1405 | 0.1457 | 0.1777 | 0.1833 | 0.1230 | 0.1129 | 0.1467 | 0.1211 | 0.2735 | 0.2128 | 0.0013 | 0.0034 | 0.0092 | 0.0433 | 0.0938 | 0.1445 | 0.1259 | 0.1491 | 0.4295 | 12 | 14 | 16 | 18 | 33 | 81 | 172 | 311 | 501 | 0.1539 | 30.24 | 4.603 | 0.5818 | 81353.0 | 57600000 | 49500000000 | 48800000000000 | 0.6313 | 0.0832 | 0.0968 | 0.0061 | 0.2891 | 0.0382 | 0.3119 | 0.2073 | 0.1514 | 0.1858 | 0.0786 | 0.1931 | 0.0396 | 0.1633 | 0.0221 | 0.0966 | 0.0084 | 0.0664 | 0.0019 | 0.0433 | 0.0002 | 0.0001 | 0.0014 | 0.0006 | 0.0029 | 0.0019 | 0.0159 | 0.0126 | 0.0664 | 0.0555 | 0.1013 | 0.0925 | 0.0752 | 0.0680 | 0.1062 | 0.0957 | 0.6305 | 0.6731 | 0.0001 | 0.0004 | 0.0027 | 0.0026 | 0.0041 | 0.0069 | 0.0213 | 0.0238 | 0.0829 | 0.0859 | 0.1261 | 0.1347 | 0.0905 | 0.1014 | 0.1246 | 0.1340 | 0.5478 | 0.5103 | 0.0002 | 0.0021 | 0.0035 | 0.0166 | 0.0752 | 0.1103 | 0.0892 | 0.1185 | 0.5844 |
| Hs 578T | Barasertib | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 15 | 1 | 153 | 736 | | 17577 | 32431 | 213.5 | 66.22 | 119.98 | 191.83 | 136 | 158 | 175 | 190 | 206 | 224 | 243 | 267 | 300 | 0.0595 | 1929 | 0.787 | 314.94 | 107.02 | 13 | 0.0531 | 934 | 0.0006 | 60.12 | 7.718 | 0.1576 | 49951.2 | 12700000 | 3480000000 | 1030000000000 | 0.4279 | 0.2038 | 0.0008 | 0.0001 | 0.0017 | 0.0000 | 0.0105 | 0.0012 | 0.0391 | 0.0061 | 0.0988 | 0.0278 | 0.1631 | 0.0552 | 0.1671 | 0.0671 | 0.1808 | 0.0927 | 0.3382 | 0.7498 | 0.0004 | 0.0001 | 0.0009 | 0.0000 | 0.0031 | 0.0002 | 0.0119 | 0.0026 | 0.0325 | 0.0130 | 0.0602 | 0.0251 | 0.0610 | 0.0279 | 0.0802 | 0.0411 | 0.7497 | 0.8899 | 0.0021 | 0.0077 | 0.0056 | 0.0131 | 0.0162 | 0.0219 | 0.0440 | 0.0848 | 0.0899 | 0.1297 | 0.1362 | 0.1822 | 0.1144 | 0.1160 | 0.1320 | 0.1510 | 0.4596 | 0.2938 | 0.0007 | 0.0020 | 0.0072 | 0.0280 | 0.0589 | 0.0957 | 0.0855 | 0.1131 | 0.6090 | 12 | 15 | 17 | 19 | 25 | 43 | 91 | 197 | 387 | 0.1336 | 21.39 | 4.248 | 0.6174 | 51191.5 | 32500000 | 25000000000 | 21700000000000 | 0.5704 | 0.1134 | 0.0562 | 0.0029 | 0.1967 | 0.0294 | 0.2199 | 0.1289 | 0.1503 | 0.1471 | 0.1472 | 0.1759 | 0.1038 | 0.1638 | 0.0562 | 0.1096 | 0.0452 | 0.1055 | 0.0244 | 0.1370 | 0.0001 | 0.0003 | 0.0006 | 0.0007 | 0.0023 | 0.0022 | 0.0121 | 0.0103 | 0.0469 | 0.0439 | 0.0761 | 0.0620 | 0.0514 | 0.0494 | 0.0790 | 0.0736 | 0.7315 | 0.7577 | 0.0001 | 0.0003 | 0.0009 | 0.0010 | 0.0024 | 0.0040 | 0.0148 | 0.0174 | 0.0598 | 0.0709 | 0.0992 | 0.1012 | 0.0685 | 0.0794 | 0.1031 | 0.1055 | 0.6513 | 0.6204 | 0.0001 | 0.0002 | 0.0016 | 0.0130 | 0.0555 | 0.0840 | 0.0645 | 0.0934 | 0.6877 |
| Hs 578T | Barasertib | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 15 | 1 | 274 | 724 | | 833 | 13982 | 37.7 | 9.22 | 181.15 | 216.84 | 28 | 30 | 32 | 34 | 36 | 38 | 40 | 44 | 50 | 0.0473 | 662 | 1.199 | 23.54 | 8.94 | 3 | 0.0732 | 61 | 0.0229 | 2.86 | 4.160 | 0.4919 | 1505.4 | 64089 | 2920000 | 142000000 | 0.4024 | 0.2135 | 0.0039 | 0.0000 | 0.0197 | 0.0000 | 0.0197 | 0.0000 | 0.0907 | 0.0156 | 0.1243 | 0.0650 | 0.1460 | 0.0728 | 0.1913 | 0.1027 | 0.2012 | 0.1352 | 0.2032 | 0.6086 | 0.0031 | 0.0000 | 0.0108 | 0.0000 | 0.0154 | 0.0000 | 0.0555 | 0.0132 | 0.0709 | 0.0505 | 0.0755 | 0.0457 | 0.1248 | 0.0721 | 0.1171 | 0.0805 | 0.5270 | 0.7380 | 0.0141 | 0.0317 | 0.0070 | 0.0317 | 0.0211 | 0.0317 | 0.0845 | 0.0794 | 0.1268 | 0.1746 | 0.1479 | 0.1587 | 0.0775 | 0.1429 | 0.1831 | 0.1111 | 0.3380 | 0.2381 | 0.0089 | 0.0417 | 0.0357 | 0.0774 | 0.0923 | 0.1220 | 0.1042 | 0.1399 | 0.3780 | 13 | 15 | 18 | 25 | 72 | 155 | 247 | 356 | 505 | 0.1047 | 25.13 | 4.988 | 0.5234 | 79833.1 | 46100000 | 31400000000 | 24300000000000 | 0.5786 | 0.1133 | 0.0295 | 0.0009 | 0.1412 | 0.0151 | 0.2513 | 0.0722 | 0.1854 | 0.1324 | 0.1750 | 0.2019 | 0.1161 | 0.2027 | 0.0537 | 0.1479 | 0.0286 | 0.1209 | 0.0191 | 0.1062 | 0.0005 | 0.0000 | 0.0021 | 0.0008 | 0.0031 | 0.0022 | 0.0102 | 0.0085 | 0.0401 | 0.0383 | 0.0610 | 0.0504 | 0.0571 | 0.0510 | 0.0875 | 0.0745 | 0.7384 | 0.7744 | 0.0004 | 0.0002 | 0.0013 | 0.0015 | 0.0054 | 0.0051 | 0.0173 | 0.0245 | 0.0542 | 0.0646 | 0.0886 | 0.0970 | 0.0864 | 0.1030 | 0.1156 | 0.1191 | 0.6309 | 0.5849 | 0.0004 | 0.0035 | 0.0025 | 0.0146 | 0.0434 | 0.0766 | 0.0726 | 0.0991 | 0.6873 |
| Hs 578T | Barasertib | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 15 | 1 | 902 | 772 | | 9805 | 18751 | 104.4 | 27.00 | 104.60 | 154.09 | 71 | 82 | 90 | 97 | 104 | 110 | 117 | 126 | 139 | 0.0633 | 1186 | 1.212 | 43.08 | 15.81 | 3 | 0.0114 | 112 | 0.0025 | 16.76 | 6.319 | 0.2683 | 11632.2 | 1370000 | 170000000 | 22000000000 | 0.4240 | 0.2204 | 0.0005 | 0.0000 | 0.0007 | 0.0000 | 0.0088 | 0.0007 | 0.0337 | 0.0037 | 0.0934 | 0.0179 | 0.1645 | 0.0465 | 0.1821 | 0.0638 | 0.1963 | 0.0903 | 0.3200 | 0.7770 | 0.0004 | 0.0000 | 0.0000 | 0.0000 | 0.0023 | 0.0001 | 0.0076 | 0.0017 | 0.0290 | 0.0096 | 0.0611 | 0.0214 | 0.0697 | 0.0191 | 0.0939 | 0.0324 | 0.7359 | 0.9158 | 0.0079 | 0.0174 | 0.0153 | 0.0349 | 0.0227 | 0.0654 | 0.0811 | 0.1497 | 0.1293 | 0.1715 | 0.1688 | 0.2035 | 0.1433 | 0.1206 | 0.1539 | 0.1206 | 0.2777 | 0.1163 | 0.0006 | 0.0026 | 0.0102 | 0.0307 | 0.0718 | 0.1201 | 0.1160 | 0.1498 | 0.4982 | 11 | 13 | 15 | 19 | 27 | 52 | 104 | 180 | 312 | 0.1458 | 19.88 | 4.207 | 0.6121 | 34684.3 | 18400000 | 13400000000 | 12900000000000 | 0.5548 | 0.1144 | 0.1016 | 0.0053 | 0.2744 | 0.0473 | 0.2848 | 0.2020 | 0.1392 | 0.1879 | 0.0992 | 0.2113 | 0.0544 | 0.1673 | 0.0200 | 0.0877 | 0.0168 | 0.0513 | 0.0096 | 0.0400 | 0.0003 | 0.0003 | 0.0008 | 0.0006 | 0.0014 | 0.0010 | 0.0124 | 0.0106 | 0.0714 | 0.0584 | 0.1103 | 0.0965 | 0.0716 | 0.0610 | 0.1148 | 0.1027 | 0.6169 | 0.6690 | 0.0000 | 0.0002 | 0.0014 | 0.0022 | 0.0034 | 0.0082 | 0.0241 | 0.0253 | 0.0928 | 0.1033 | 0.1418 | 0.1582 | 0.0932 | 0.1072 | 0.1495 | 0.1476 | 0.4938 | 0.4478 | 0.0004 | 0.0007 | 0.0034 | 0.0164 | 0.0820 | 0.1252 | 0.0852 | 0.1331 | 0.5536 |
| Hs 578T | Barasertib | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 15 | 1 | 1140 | 800 | | 415 | 10014 | 37.5 | 8.37 | 298.79 | 356.44 | 26 | 30 | 32 | 35 | 37 | 40 | 42 | 45 | 48 | 0.0520 | 521 | 0.700 | 202.20 | 35.61 | 2 | 1.1663 | 484 | 0.0170 | 4.33 | 4.301 | 0.4484 | 1479.7 | 60857.1 | 2600000 | 115000000 | 0.3546 | 0.2708 | 0.0000 | 0.0000 | 0.0083 | 0.0000 | 0.0373 | 0.0025 | 0.1037 | 0.0176 | 0.2241 | 0.0529 | 0.2033 | 0.0856 | 0.1867 | 0.1058 | 0.1743 | 0.1738 | 0.0622 | 0.5617 | 0.0000 | 0.0000 | 0.0032 | 0.0000 | 0.0127 | 0.0025 | 0.0538 | 0.0173 | 0.0854 | 0.0519 | 0.0918 | 0.0765 | 0.1076 | 0.0914 | 0.1424 | 0.1136 | 0.5032 | 0.6469 | 0.0533 | 0.2500 | 0.0800 | 0.0000 | 0.0533 | 0.0000 | 0.2000 | 0.3750 | 0.1600 | 0.2500 | 0.1467 | 0.1250 | 0.2133 | 0.0000 | 0.0533 | 0.0000 | 0.0400 | 0.0000 | 0.0000 | 0.0000 | 0.0291 | 0.0825 | 0.1311 | 0.1602 | 0.1408 | 0.1748 | 0.2816 | 16 | 19 | 26 | 56 | 134 | 250 | 397 | 574 | 843 | 0.0362 | 50.93 | 5.899 | 0.4283 | 216312.0 | 203000000 | 220000000000 | 261000000000000 | 0.5151 | 0.1616 | 0.0713 | 0.0006 | 0.1940 | 0.0107 | 0.2691 | 0.1146 | 0.2078 | 0.1740 | 0.1352 | 0.1960 | 0.0701 | 0.1829 | 0.0250 | 0.1140 | 0.0163 | 0.1146 | 0.0113 | 0.0926 | 0.0002 | 0.0000 | 0.0002 | 0.0009 | 0.0022 | 0.0018 | 0.0115 | 0.0112 | 0.0583 | 0.0497 | 0.0937 | 0.0790 | 0.0718 | 0.0645 | 0.0976 | 0.0919 | 0.6644 | 0.7012 | 0.0003 | 0.0007 | 0.0018 | 0.0045 | 0.0055 | 0.0111 | 0.0210 | 0.0236 | 0.0735 | 0.0748 | 0.1104 | 0.1219 | 0.0921 | 0.0890 | 0.1052 | 0.1126 | 0.5902 | 0.5618 | 0.0003 | 0.0005 | 0.0027 | 0.0156 | 0.0648 | 0.1058 | 0.0826 | 0.1017 | 0.6260 |
| Hs 578T | Barasertib | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 15 | 1 | 854 | 856 | | 7221 | 14570 | 49.4 | 17.53 | 78.00 | 136.28 | 28 | 34 | 38 | 43 | 47 | 52 | 58 | 64 | 73 | 0.0925 | 1347 | 0.564 | 226.82 | 39.32 | 13 | 0.0867 | 626 | 0.0060 | 6.82 | 5.419 | 0.3768 | 2746.4 | 169000 | 11300000 | 819000000 | 0.4385 | 0.1979 | 0.0021 | 0.0002 | 0.0092 | 0.0013 | 0.0509 | 0.0036 | 0.1206 | 0.0209 | 0.1835 | 0.0519 | 0.1998 | 0.1171 | 0.1729 | 0.1192 | 0.1266 | 0.1517 | 0.1344 | 0.5342 | 0.0004 | 0.0000 | 0.0012 | 0.0005 | 0.0037 | 0.0013 | 0.0217 | 0.0112 | 0.0562 | 0.0266 | 0.0864 | 0.0540 | 0.0848 | 0.0579 | 0.1085 | 0.0691 | 0.6371 | 0.7796 | 0.0039 | 0.0097 | 0.0073 | 0.0154 | 0.0194 | 0.0328 | 0.0682 | 0.0936 | 0.1094 | 0.1380 | 0.1510 | 0.1979 | 0.1292 | 0.1342 | 0.1549 | 0.1467 | 0.3567 | 0.2317 | 0.0017 | 0.0026 | 0.0125 | 0.0408 | 0.0755 | 0.1098 | 0.1078 | 0.1329 | 0.5163 | 11 | 13 | 15 | 17 | 20 | 26 | 46 | 104 | 234 | 0.1860 | 10.58 | 3.510 | 0.6862 | 24655.2 | 13200000 | 8940000000 | 7000000000000 | 0.6410 | 0.1101 | 0.1548 | 0.0039 | 0.3289 | 0.0394 | 0.2946 | 0.2229 | 0.1131 | 0.2327 | 0.0565 | 0.2189 | 0.0298 | 0.1433 | 0.0134 | 0.0671 | 0.0074 | 0.0493 | 0.0015 | 0.0224 | 0.0008 | 0.0002 | 0.0008 | 0.0005 | 0.0032 | 0.0053 | 0.0201 | 0.0138 | 0.0823 | 0.0766 | 0.1173 | 0.0994 | 0.0839 | 0.0713 | 0.1284 | 0.1266 | 0.5631 | 0.6063 | 0.0003 | 0.0007 | 0.0023 | 0.0021 | 0.0058 | 0.0053 | 0.0229 | 0.0248 | 0.1011 | 0.1076 | 0.1308 | 0.1522 | 0.0995 | 0.0995 | 0.1485 | 0.1501 | 0.4889 | 0.4577 | 0.0000 | 0.0023 | 0.0053 | 0.0197 | 0.0978 | 0.1169 | 0.0934 | 0.1436 | 0.5211 |