Project Explorer

Metrics other than potency reveal systematic variation in responses to cancer drugs

Mohammad Fallahi-Sichani1, Saman Honarnejad1, Laura M. Heiser2, Joe W. Gray2 and Peter K. Sorger1

1 HMS LINCS Center, Harvard Medical School, Boston, MA; 2 Department of Biomedical Engineering, Oregon Health and Science University, Portland, OR

Nat Chem Biol (2013) 9, 708-714.
doi:10.1038/nchembio.1337 / PMID:24013279 / PMCID:PMC3947796

Available data and software

Data All raw imaging data and calculated fluorescence intensities across dose for 6 drugs in 4 breast cell lines at 2 timepoints (HMS Dataset #20136). Details Download (.xlsx)
Signatures The results of multi-parametric analysis of dose-response data for 2789 drug-cell line combinations (HMS Dataset #20120). Details Download (.xlsx)
Software A link to our HMS LINCS GitHub for access to the code underlying the interactive data browsers available on this project exploration website. hmslincs at GitHub