SKI II - Small Molecule (ID:10452-101)
| HMS LINCS ID: |
10452-101
|
| Name: | SKI II |
| Alternative Names: | |
| LINCS ID: | |
| PubChem CID: | 753704 |
| ChEBI ID: | |
| ChEMBL ID: | |
| Molecular Mass: | 302.03 |
| InChi: | InChI=1S/C15H11ClN2OS/c16-11-3-1-10(2-4-11)14-9-20-15(18-14)17-12-5-7-13(19)8-6-12/h1-9,19H,(H,17,18) |
| InChi Key: | ZFGXZJKLOFCECI-UHFFFAOYSA-N |
| SMILES: | C1=CC(=CC=C1C2=CSC(=N2)NC3=CC=C(C=C3)O)Cl |
| Relevant Citations: | |
| Comments: | |
| Date Publicly Available: | |
| Most Recent Update: | 2016-04-04 |
Target Affinity:
(see Study 20000)| Target Affinity Spectrum Value | HUGO Gene Name |
|---|---|
VCP | |
2 (equivalent to 100 nM ≤ Kd < 1µM) | ALOX5, SPHK1, SPHK2 |
3 (equivalent to 1µM ≤ Kd < 10 µM) | MAP4K4, MAPKAPK2, MAPT, MINK1, PIM3 |
10 (confirmed non-binding) |
Batch Information for HMSL10452-101-1:
| HMS LINCS Batch ID: | 10452-101-1 |
| Provider: | Selleck Chemicals |
| Provider Batch ID: | S717601 |
| Salt: | 101 |
| Molecular Formula: | C15H11ClN2OS |
| Molecular Weight: | 302.78 |
| Purity: | |
| Purification Method: | |
| Chemical Synthesis Reference: | |
| Comments: | |
| Date Publicly Available: | 2015-08-27 |
| Most Recent Update: | 2016-04-04 |
HMS QC Testing Events for HMSL10452-101-1:
| Date | HMS QC Outcome | Comment | Files |
|---|---|---|---|
| 08/31/2015 | PASS | HMSL10452-101-1_LCMS.pdf |
(Kd <100 nM)