PF-06463922 - Small Molecule (ID:10383-101)
| HMS LINCS ID: |
10383-101
|
| Name: | PF-06463922 |
| Alternative Names: | |
| LINCS ID: | |
| PubChem CID: | 71731823 |
| ChEBI ID: | |
| ChEMBL ID: | |
| Molecular Mass: | 406.16 |
| InChi: | InChI=1S/C21H19FN6O2/c1-11-15-7-13(22)4-5-14(15)21(29)27(2)10-16-19(17(8-23)28(3)26-16)12-6-18(30-11)20(24)25-9-12/h4-7,9,11H,10H2,1-3H3,(H2,24,25)/t11-/m1/s1 |
| InChi Key: | IIXWYSCJSQVBQM-LLVKDONJSA-N |
| SMILES: | C[C@@H]1C2=C(C=CC(=C2)F)C(=O)N(CC3=NN(C(=C3C4=CC(=C(N=C4)N)O1)C#N)C)C |
| Relevant Citations: | |
| Comments: | |
| Date Publicly Available: | |
| Most Recent Update: | 2016-04-04 |
Target Affinity:
(see Study 20000)| Target Affinity Spectrum Value | HUGO Gene Name |
|---|---|
ALK, FER, FES, FRK, LTK, NTRK1, NTRK2, NTRK3, PTK2, PTK2B, ROS1, TNK2 |
Batch Information for HMSL10383-101-1:
| HMS LINCS Batch ID: | 10383-101-1 |
| Provider: | MedChem Express |
| Provider Batch ID: | 15586 |
| Salt: | 101 |
| Molecular Formula: | C21H19FN6O2 |
| Molecular Weight: | 406.41 |
| Purity: | |
| Purification Method: | |
| Chemical Synthesis Reference: | |
| Comments: | |
| Date Publicly Available: | 2015-08-27 |
| Most Recent Update: | 2016-04-04 |
HMS QC Testing Events for HMSL10383-101-1:
| Date | HMS QC Outcome | Comment | Files |
|---|---|---|---|
| 08/31/2015 | PASS | HMSL10383-101-1_LCMS.pdf |
(Kd <100 nM)