GDC-0980 - Small Molecule (ID:10234-101)

HMS LINCS ID: 10234-101
Name: GDC-0980
Alternative Names: RG7422
LINCS ID: LSM-4257
PubChem CID: 66694608
ChEBI ID:
ChEMBL ID:
Molecular Mass: 498.22
InChi: InChI=1S/C23H30N8O3S/c1-14-17(13-29-3-5-31(6-4-29)22(33)15(2)32)35-19-18(14)27-20(16-11-25-23(24)26-12-16)28-21(19)30-7-9-34-10-8-30/h11-12,15,32H,3-10,13H2,1-2H3,(H2,24,25,26)
InChi Key: YOVVNQKCSKSHKT-UHFFFAOYSA-N
SMILES: CC1=C(SC2=C1N=C(N=C2N3CCOCC3)C4=CN=C(N=C4)N)CN5CCN(CC5)C(=O)C(C)O
Relevant Citations:
Comments:
Date Publicly Available:
Most Recent Update: 2016-04-04

Target Affinity:

(see Study 20000)
Target Affinity Spectrum Value HUGO Gene Name
1
(Kd <100 nM)
MTOR, PIK3CA, PIK3CB, PIK3CD, PIK3CG
2
(equivalent to 100 nM ≤ Kd < 1µM)
FGR, MAP3K9, PIK3C2B, SYK
3
(equivalent to 1µM ≤ Kd < 10 µM)
PIK3C2A, PIK3C3
10
(confirmed non-binding)
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Batch Information for HMSL10234-101-2:

HMS LINCS Batch ID: 10234-101-2
Provider: MedChem Express
Provider Batch ID: 06524
Salt: 101
Molecular Formula: C23H30N8O3S
Molecular Weight: 498.6
Purity:
Purification Method:
Chemical Synthesis Reference:
Comments:
Date Publicly Available: 2015-06-17
Most Recent Update: 2016-04-04

HMS QC Testing Events for HMSL10234-101-2:

Date HMS QC Outcome Comment Files
08/31/2015 PASS HMSL10234-101-2_LCMS.pdf