AZD-1480 - Small Molecule (ID:10139-101)

HMS LINCS ID: 10139-101
Name: AZD-1480
Alternative Names:
LINCS ID: LSM-1140
PubChem CID: 46861588
ChEBI ID:
ChEMBL ID:
Molecular Mass: 348.10
InChi: InChI=1S/C14H14ClFN8/c1-7-3-11(24-23-7)21-13-10(15)6-19-14(22-13)20-8(2)12-17-4-9(16)5-18-12/h3-6,8H,1-2H3,(H3,19,20,21,22,23,24)
InChi Key: PDOQBOJDRPLBQU-UHFFFAOYSA-N
SMILES: CC1=CC(=NN1)NC2=NC(=NC=C2Cl)NC(C)C3=NC=C(C=N3)F
Relevant Citations:
Comments:
Date Publicly Available:
Most Recent Update: 2016-04-04

Target Affinity:

(see Study 20000)
Target Affinity Spectrum Value HUGO Gene Name
1
(Kd <100 nM)
JAK2, NTRK1, STAT3, STAT5A
3
(equivalent to 1µM ≤ Kd < 10 µM)
JAK3

Batch Information for HMSL10139-101-1:

HMS LINCS Batch ID: 10139-101-1
Provider: Haoyuan chemexpress
Provider Batch ID: HM-060_10-20110418
Salt: 101
Molecular Formula: C14H14ClFN8
Molecular Weight: 348.77
Purity:
Purification Method:
Chemical Synthesis Reference:
Comments:
Date Publicly Available: 2011-07-15
Most Recent Update: 2016-04-04

HMS QC Testing Events for HMSL10139-101-1:

Date HMS QC Outcome Comment Files
04/13/2015 PASS HMSL10139-101-1_LCMS.pdf
11/14/2011 PASS None