Amuvatinib - Small Molecule (ID:10118-101)

HMS LINCS ID: 10118-101
Name: Amuvatinib
Alternative Names: MP470
LINCS ID: LSM-1118
PubChem CID: 11282283
ChEBI ID:
ChEMBL ID:
Molecular Mass: 447.14
InChi: InChI=1S/C23H21N5O3S/c32-23(24-12-15-5-6-18-19(11-15)30-14-29-18)28-9-7-27(8-10-28)22-21-20(25-13-26-22)16-3-1-2-4-17(16)31-21/h1-6,11,13H,7-10,12,14H2,(H,24,32)
InChi Key: FOFDIMHVKGYHRU-UHFFFAOYSA-N
SMILES: C1CN(CCN1C2=NC=NC3=C2OC4=CC=CC=C43)C(=S)NCC5=CC6=C(C=C5)OCO6
Relevant Citations:
Comments:
Date Publicly Available:
Most Recent Update: 2016-04-04

Target Affinity:

(see Study 20000)
Target Affinity Spectrum Value HUGO Gene Name
2
(equivalent to 100 nM ≤ Kd < 1µM)
KIT, PDGFRA

Batch Information for HMSL10118-101-1:

HMS LINCS Batch ID: 10118-101-1
Provider: Haoyuan chemexpress
Provider Batch ID: HY-10206-20100602
Salt: 101
Molecular Formula: C23H21N5O3S
Molecular Weight: 447.51
Purity:
Purification Method:
Chemical Synthesis Reference:
Comments:
Date Publicly Available: 2011-07-15
Most Recent Update: 2016-04-04

HMS QC Testing Events for HMSL10118-101-1:

Date HMS QC Outcome Comment Files
04/13/2015 PASS HMSL10118-101-1_LCMS.pdf
11/14/2011 PASS None