CGP60474 - Small Molecule (ID:10025-101)

HMS LINCS ID: 10025-101
Name: CGP60474
Alternative Names: MLS000911536; SMR000463552
LINCS ID: LSM-1025
PubChem CID: 644215
ChEBI ID:
ChEMBL ID: 300389
Molecular Mass: 355.12
InChi: InChI=1S/C18H18ClN5O/c19-14-3-1-4-15(12-14)23-18-22-9-6-16(24-18)13-5-8-21-17(11-13)20-7-2-10-25/h1,3-6,8-9,11-12,25H,2,7,10H2,(H,20,21)(H,22,23,24)
InChi Key: IYNDTACKOAXKBJ-UHFFFAOYSA-N
SMILES: C1=CC(=CC(=C1)Cl)NC2=NC=CC(=N2)C3=CC(=NC=C3)NCCCO
Relevant Citations:
Comments:
Date Publicly Available:
Most Recent Update: 2016-04-04

Target Affinity:

(see Study 20000)
Target Affinity Spectrum Value HUGO Gene Name
1
(Kd <100 nM)
CDK1, CDK2, Dyrk1a
2
(equivalent to 100 nM ≤ Kd < 1µM)
CDK5, CDK5R1, MTOR
3
(equivalent to 1µM ≤ Kd < 10 µM)
MAPT
10
(confirmed non-binding)
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Batch Information for HMSL10025-101-1:

HMS LINCS Batch ID: 10025-101-1
Provider: Haoyuan chemexpress
Provider Batch ID: HM-088_8-20101230
Salt: 101
Molecular Formula: C18H18ClN5O
Molecular Weight: 355.82
Purity:
Purification Method:
Chemical Synthesis Reference:
Comments:
Date Publicly Available: 2011-07-15
Most Recent Update: 2016-04-04

HMS QC Testing Events for HMSL10025-101-1:

Date HMS QC Outcome Comment Files
03/13/2015 PASS HMSL10025-101-1_LCMS.pdf