AT-7519 - Small Molecule (ID:10004-101)

HMS LINCS ID: 10004-101
Name: AT-7519
Alternative Names:
LINCS ID: LSM-1004
PubChem CID: 11338033
ChEBI ID:
ChEMBL ID: 445813
Molecular Mass: 381.08
InChi: InChI=1S/C16H17Cl2N5O2/c17-10-2-1-3-11(18)13(10)15(24)22-12-8-20-23-14(12)16(25)21-9-4-6-19-7-5-9/h1-3,8-9,19H,4-7H2,(H,20,23)(H,21,25)(H,22,24)
InChi Key: OVPNQJVDAFNBDN-UHFFFAOYSA-N
SMILES: C1CNCCC1NC(=O)C2=C(C=NN2)NC(=O)C3=C(C=CC=C3Cl)Cl
Relevant Citations:
Comments:
Date Publicly Available:
Most Recent Update: 2016-04-04

Target Affinity:

(see Study 20000)
Target Affinity Spectrum Value HUGO Gene Name
1
(Kd <100 nM)
CASK, CCNA1, CCNA2, CDK11A, CDK11B, CDK13, CDK14, CDK15, CDK16, CDK17, CDK18, CDK2, CDK3, CDK4, CDK7, CDK9, CDKL5, CDKN3, GSK3A, GSK3B, ICK, MAK, MAPK7, TAOK2, TAOK3
2
(equivalent to 100 nM ≤ Kd < 1µM)
CCNB1, CCNB2, CCNB3, CCND1, CCND3, CDK1, CDK5, CDK6, CLK1, CLK3, DYRK1A, DYRK1B, MAPK15, TAOK1
3
(equivalent to 1µM ≤ Kd < 10 µM)
CAMKK2, CDK19, CDKL2, CLK2, CLK4, DCLK2, DCLK3, DMPK, DYRK2, SLK, TLK1
10
(confirmed non-binding)
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Batch Information for HMSL10004-101-1:

HMS LINCS Batch ID: 10004-101-1
Provider: Haoyuan chemexpress
Provider Batch ID: HY-999-20100925
Salt: 101
Molecular Formula: C16H17Cl2N5O2
Molecular Weight: 382.24
Purity:
Purification Method:
Chemical Synthesis Reference:
Comments:
Date Publicly Available: 2011-07-15
Most Recent Update: 2016-04-04

HMS QC Testing Events for HMSL10004-101-1:

Date HMS QC Outcome Comment Files
02/22/2011 PASS None