Evaluation of the sensitivities of six triple-negative breast cancer (TNBC) cell lines to 23 different PI3K/AKT/mTOR inhibitors or to a MEK inhibitor (trametinib). Dataset 1 of 2: GR values. - Dataset (ID:20364)

Small Molecules Studied

  • 24 Small Molecules
HMS LINCS ID Name Alternative Names LINCS ID Structure Image PubChem CID
10007-1 AZD8055 LSM-1007 25262965
10047-1 Pictilisib
Pictrelisib; GDC-0941; RG-7321
LSM-1047 17755052
10052-1 Sirolimus
Rapamycin
LSM-1052 5040
10053-1 ZSTK474 LSM-1053 11647372
10054-1 AS605240 LSM-42784 24906273
10055-1 BX-912 LSM-1055 11754511
10057-1 MK2206 LSM-1057 24964624
10059-1 AZD-6482
KIN001-193
LSM-1059 44137675
10064-1 WYE-125132 LSM-1064 25260757
10079-1 Torin1 LSM-1079 49836027
10080-1 Torin2 LSM-1080 51358113
10081-1 KIN001-244 LSM-1081 49766501
10126-1 PI103 LSM-1126 9884685
10142-1 Trametinib
GSK-1120212; GSK1120212; GSK1120212B; JTP-74057
LSM-1143 11707110
10146-3 Omipalisib
GSK2126458; GSK2126458A
LSM-1147 25167777
10147-1 Buparlisib
BKM120; NVP-BKM120
LSM-1148 16654980
10148-1 XL147
SAR245408
LSM-1149 52914932
10171-1 TGX221 LSM-1172 9907093
10190-1 PIK-93 LSM-1191 6852167
10204-1 CAL-101 LSM-1205 11625818
10232-1 Dactolisib
BEZ235; NVP-BEZ235
LSM-4255 11977753
10233-1 Alpelisib
BYL719
LSM-4256 56649450
10234-1 GDC-0980
RG7422
LSM-4257 66694608
10235-1 Everolimus
RAD001
LSM-4258 53398658
  • 24 Small Molecules