Breast Cancer Deubiquitinating Enzyme (DUB) Inhibitor Profiling: Fixed-cell GR measures of 21 breast cell lines to 32 small molecule perturbagens. Dataset 2 of 2: Calculated dose response metrics. - Dataset (ID:20351)

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Cell Small Molecule Treatment Duration GR50 GRmax GR_AOC GEC50 GRinf hGR
PDX1328 Pevonedistat 72
inf
-0.7089 -0.4505 0.0000 1.0000 0.0100
PDX1328 SB1-F-22 72
inf
1.0347 -0.2404 0.0000 1.0000 0.0100
BT-20 IU1 72
inf
1.1490 -0.1850 0.0000 1.0000 0.0100
MDA-MB-361 STK547622 72
inf
1.0471 -0.1279 0.0000 1.0000 0.0100
MDA-MB-134-VI GW7647 72
inf
1.0004 -0.0983 0.0000 1.0000 0.0100
PDX1328 GW7647 72
inf
0.8376 -0.0784 0.0000 1.0000 0.0100
HCC202 GW7647 72
inf
0.8031 -0.0688 0.0000 1.0000 0.0100
PDX1258 GW7647 72
inf
1.0702 -0.0651 0.0000 1.0000 0.0100
BT-20 GW7647 72
inf
0.7093 -0.0625 0.0000 1.0000 0.0100
MDA-MB-361 HY-17542 72
inf
0.8632 -0.0548 0.0000 1.0000 0.0100
BT-20 STK547622 72
inf
1.1526 -0.0532 0.0000 1.0000 0.0100
HCC1937 STK547622 72
inf
1.0316 -0.0512 0.0000 1.0000 0.0100
MDA-MB-361 IU1 72
inf
0.7838 -0.0464 0.0000 1.0000 0.0100
HCC1937 HY-17542 72
inf
0.9422 -0.0439 0.0000 1.0000 0.0100
HCC1954 GW7647 72
53.2192077737
0.5700 -0.0367 66.2968 -1.0000 5.0000
BT-20 SB1-F-22 72
inf
0.8486 -0.0325 0.0000 1.0000 0.0100
Hs 578T GW7647 72
inf
0.8977 -0.0280 0.0000 1.0000 0.0100
PDXHCI002 GW7647 72
inf
0.7629 -0.0251 0.0000 0.9997 0.0100
HCC202 IU1 72
inf
0.7641 -0.0242 0.0000 0.9954 0.0100
Hs 578T Doxycycline 72
inf
1.3436 -0.0222 0.0000 1.0000 0.0100
HCC1500 GW7647 72
42.1427904431
0.1820 -0.0218 72.6766 -0.9087 1.9008
Hs 578T HY-17542 72
inf
0.9246 -0.0205 0.0000 1.0000 0.0100
HCC202 USP7-IN-1 72
inf
0.8501 -0.0200 0.0000 1.0000 0.0100
MDA-MB-231 GW7647 72
inf
0.9369 -0.0195 0.0000 1.0000 0.0100
BT-20 HY-17542 72
inf
1.0099 -0.0181 0.0000 1.0000 0.0100
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