Breast Cancer Deubiquitinating Enzyme (DUB) Inhibitor Profiling: Fixed-cell GR measures of 21 breast cell lines to 32 small molecule perturbagens. Dataset 2 of 2: Calculated dose response metrics. - Dataset (ID:20351)

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Cell Small Molecule Treatment Duration GR50 GRmax GR_AOC GEC50 GRinf hGR
T47D LDN57444 72
5.98029149748
 -0.4896 0.3206 18.7611 -0.9206 0.9133
T47D MI-2 72
0.443682151865
 -0.4886 0.7738 0.5068 -0.4479 4.8114
T47D ML-323 72
13.4276900688
 0.0649 0.2011 60.0348 -0.9911 0.7296
T47D Pevonedistat 72
0.0485963385259
 -0.0543 0.9154 0.0536 -0.1256 2.2893
T47D PB49673382 72
3.64102000587
 -0.0634 0.3384 3.7853 -0.0626 3.0337
T47D 5-(4-fluorophenyl)-3-hydroxy-4-(5-methyl-2-furoyl)-1-(3-pyridinylmethyl)-1,5-dihydro-2H-pyrrol-2-one 72
inf
 0.9421 0.0700 0.0000 0.9383 0.0100
T47D SB1-F-21 72
0.605682620995
 -0.5948 0.6994 0.9625 -0.5534 1.6087
T47D SB1-F-22 72
156.804339896
 0.7134 0.0621 286.2396 -0.2481 0.6696
T47D SJB2-043 72
0.418884416082
 -0.3821 0.5842 0.6165 -0.3642 1.4158
T47D SJB3-019A 72
0.197447266274
 -0.5628 0.9021 0.3562 -0.5619 1.2767
T47D STK547622 72
inf
 0.9428 0.0182 0.0000 0.9914 0.0100
T47D Vialinin A 72
5.62945811704
 -0.3676 0.2949 7.5227 -0.3834 1.9635
T47D Degrasyn 72
1.65739001923
 -0.6099 0.5646 2.1976 -0.5077 2.4843
T47D Sepantronium 72
0.0256731457276
 -0.5680 1.2354 0.0464 -0.5390 1.2377
T47D b-AP15 72
0.150241064877
 -0.5598 0.9131 0.1831 -0.4234 3.0977
T47D Doxycycline 72
15.8755936591
 -0.2262 0.2230 24.9860 -0.5704 1.6784
T47D Mitoxantrone 72
5.66232793817e-05
 -0.4434 1.1468 0.0899 -1.0000 0.1491
T47D P22077 72
3.7378149825
 -0.5532 0.4192 4.7330 -0.5353 3.0835
T47D Pimozide 72
7.11853496187
 -0.5532 0.3575 16.3429 -1.0000 1.3219
T47D Spautin-1 72
6.81498097187
 0.2682 0.2402 3.7541 0.2153 0.9443
T47D Trifluoperazine 72
7.53715146312
 -0.4917 0.3754 11.9806 -0.6568 1.8099
T47D z-VAE(OMe)-fmk 72
inf
 0.9468 0.0261 0.0000 0.9749 0.0100