Breast Cancer Deubiquitinating Enzyme (DUB) Inhibitor Profiling: Fixed-cell GR measures of 21 breast cell lines to 32 small molecule perturbagens. Dataset 1 of 2: Normalized growth rate inhibition values. - Dataset (ID:20350)
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| Cell | Small Molecule | Small Mol Concentration (uM) | Mean Normalized Growth Rate Inhibition (GR) Value | Increased Fraction Dead |
|---|---|---|---|---|
| HCC1419 | z-VAE(OMe)-fmk | 31.6 | 0.9275 | 0.00141 |
| HCC1419 | z-VAE(OMe)-fmk | 50.0 | 1.0231 | 0.00787 |
| HCC1428 | 1247825-37-1 | 0.009992797 | 0.9314 | 0.00104 |
| HCC1428 | 1247825-37-1 | 0.0316 | 1.0579 | 0.00345 |
| HCC1428 | 1247825-37-1 | 0.099927974 | 0.9813 | 0.00623 |
| HCC1428 | 1247825-37-1 | 0.316 | 0.7588 | 0.00196 |
| HCC1428 | 1247825-37-1 | 0.999279741 | 0.9626 | 0.00127 |
| HCC1428 | 1247825-37-1 | 3.16 | 0.6948 | 0.01600 |
| HCC1428 | 1247825-37-1 | 9.992797406 | 0.1751 | 0.04006 |
| HCC1428 | 1247825-37-1 | 31.6 | -0.2477 | 0.23303 |
| HCC1428 | 1247825-37-1 | 50.0 | -0.1424 | 0.22498 |
| HCC1428 | b-AP15 | 0.009992797 | 1.0856 | 0.00178 |
| HCC1428 | b-AP15 | 0.0316 | 0.8978 | -0.00137 |
| HCC1428 | b-AP15 | 0.099927974 | 0.1483 | 0.06214 |
| HCC1428 | b-AP15 | 0.316 | -0.3332 | 0.34774 |
| HCC1428 | b-AP15 | 0.999279741 | -0.2583 | 0.21177 |
| HCC1428 | b-AP15 | 3.16 | -0.4527 | 0.47105 |
| HCC1428 | b-AP15 | 9.992797406 | -0.6924 | 0.70722 |
| HCC1428 | b-AP15 | 31.6 | -0.7164 | 0.71376 |
| HCC1428 | b-AP15 | 50.0 | -0.6735 | 0.68772 |
| HCC1428 | USP7-IN-1 | 0.009992797 | 1.1758 | 0.00034 |
| HCC1428 | USP7-IN-1 | 0.0316 | 1.0051 | 0.00188 |
| HCC1428 | USP7-IN-1 | 0.099927974 | 0.8776 | -0.01337 |
| HCC1428 | USP7-IN-1 | 0.316 | 1.0017 | 0.01166 |
| HCC1428 | USP7-IN-1 | 0.999279741 | 0.7314 | 0.01330 |