Breast Cancer Deubiquitinating Enzyme (DUB) Inhibitor Profiling: Fixed-cell GR measures of 21 breast cell lines to 32 small molecule perturbagens. Dataset 1 of 2: Normalized growth rate inhibition values. - Dataset (ID:20350)

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Cell Small Molecule Small Mol Concentration (uM) Mean Normalized Growth Rate Inhibition (GR) Value Increased Fraction Dead
T47D PB49673382
0.316
 0.9485 -0.00448
T47D PB49673382
0.999279741
 0.9359 -0.00945
T47D PB49673382
3.16
 0.6173 -0.00362
T47D PB49673382
9.992797406
 -0.0282 0.13416
T47D PB49673382
31.6
 -0.0437 0.03852
T47D PB49673382
50.0
 -0.0634 0.02912
T47D Pimozide
0.009992797
 1.0197 -0.00614
T47D Pimozide
0.0316
 0.9160 -0.00407
T47D Pimozide
0.099927974
 0.9899 -0.00728
T47D Pimozide
0.316
 0.8199 -0.00395
T47D Pimozide
0.999279741
 0.8340 -0.00299
T47D Pimozide
3.16
 0.7542 -0.00039
T47D Pimozide
9.992797406
 0.4212 0.01419
T47D Pimozide
31.6
 -0.5460 0.57151
T47D Pimozide
50.0
 -0.5532 0.60684
T47D 5-(4-fluorophenyl)-3-hydroxy-4-(5-methyl-2-furoyl)-1-(3-pyridinylmethyl)-1,5-dihydro-2H-pyrrol-2-one
0.009992797
 1.0044 -0.00666
T47D 5-(4-fluorophenyl)-3-hydroxy-4-(5-methyl-2-furoyl)-1-(3-pyridinylmethyl)-1,5-dihydro-2H-pyrrol-2-one
0.0316
 0.6220 0.01499
T47D 5-(4-fluorophenyl)-3-hydroxy-4-(5-methyl-2-furoyl)-1-(3-pyridinylmethyl)-1,5-dihydro-2H-pyrrol-2-one
0.099927974
 0.9920 -0.00163
T47D 5-(4-fluorophenyl)-3-hydroxy-4-(5-methyl-2-furoyl)-1-(3-pyridinylmethyl)-1,5-dihydro-2H-pyrrol-2-one
0.316
 1.0400 -0.00312
T47D 5-(4-fluorophenyl)-3-hydroxy-4-(5-methyl-2-furoyl)-1-(3-pyridinylmethyl)-1,5-dihydro-2H-pyrrol-2-one
0.999279741
 0.9161 -0.00499
T47D 5-(4-fluorophenyl)-3-hydroxy-4-(5-methyl-2-furoyl)-1-(3-pyridinylmethyl)-1,5-dihydro-2H-pyrrol-2-one
3.16
 0.9995 -0.00553
T47D 5-(4-fluorophenyl)-3-hydroxy-4-(5-methyl-2-furoyl)-1-(3-pyridinylmethyl)-1,5-dihydro-2H-pyrrol-2-one
9.992797406
 0.9563 -0.00834
T47D 5-(4-fluorophenyl)-3-hydroxy-4-(5-methyl-2-furoyl)-1-(3-pyridinylmethyl)-1,5-dihydro-2H-pyrrol-2-one
31.6
 0.9421 -0.00281
T47D 5-(4-fluorophenyl)-3-hydroxy-4-(5-methyl-2-furoyl)-1-(3-pyridinylmethyl)-1,5-dihydro-2H-pyrrol-2-one
50.0
 0.9722 0.04024
T47D SB1-F-21
0.009992797
 0.9588 -0.00382