Breast Cancer Profiling Project, Drug Sensitivity phase I: Fixed-cell GR measures of 35 breast cell lines to 34 small molecule perturbagens from library plate I. Dataset 1 of 2: Normalized growth rate inhibition values - Dataset - HMS LINCS Database

Breast Cancer Profiling Project, Drug Sensitivity phase I: Fixed-cell GR measures of 35 breast cell lines to 34 small molecule perturbagens from library plate I. Dataset 1 of 2: Normalized growth rate inhibition values - Dataset (ID:20343)

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Cell	Small Molecule	Small Mol Concentration (uM)	Primary Target	Pathway	Mean Normalized Growth Rate Inhibition Value	Increased Fraction Dead
BT-20	Palbociclib	0.1	CDK4/6	Cell cycle	0.3557	0.03619
BT-20	AZD7762	0.1	CHK1/2	Cell cycle	1.1714	0.04490
BT-20	Abemaciclib	1.0	CDK4/6	Cell cycle	0.2233	0.00560
BT-20	Palbociclib	0.031623	CDK4/6	Cell cycle	0.5715	0.01511
BT-20	AZD7762	0.001	CHK1/2	Cell cycle	1.1198	-0.00253
BT-20	AZD7762	0.031623	CHK1/2	Cell cycle	1.2229	0.01175
BT-20	Abemaciclib	0.01	CDK4/6	Cell cycle	0.7022	-0.00034
BT-20	Abemaciclib	0.31623	CDK4/6	Cell cycle	0.2635	0.00452
BT-20	Palbociclib	0.00031623	CDK4/6	Cell cycle	1.0619	-0.00163
BT-20	Palbociclib	0.01	CDK4/6	Cell cycle	0.8023	0.00566
BT-20	Palbociclib	1.0	CDK4/6	Cell cycle	0.2044	0.04646
BT-20	Palbociclib	3.1623	CDK4/6	Cell cycle	0.1624	0.05010
BT-20	AZD7762	0.0031623	CHK1/2	Cell cycle	1.2431	-0.00726
BT-20	AZD7762	0.01	CHK1/2	Cell cycle	1.2200	0.00225
BT-20	Abemaciclib	0.001	CDK4/6	Cell cycle	0.9370	-0.00149
BT-20	Abemaciclib	0.0031623	CDK4/6	Cell cycle	0.8833	-0.00527
BT-20	Abemaciclib	0.031623	CDK4/6	Cell cycle	0.4936	-0.00426
BT-20	Abemaciclib	0.1	CDK4/6	Cell cycle	0.3565	0.00950
BT-20	Abemaciclib	3.1623	CDK4/6	Cell cycle	0.1622	0.01068
BT-20	Abemaciclib	10.0	CDK4/6	Cell cycle	-0.2160	0.37259
BT-20	Palbociclib	0.001	CDK4/6	Cell cycle	1.0987	-0.00539
BT-20	Palbociclib	0.0031623	CDK4/6	Cell cycle	0.9966	0.00011
BT-20	Palbociclib	0.31623	CDK4/6	Cell cycle	0.2359	0.04751
BT-20	AZD7762	1.0	CHK1/2	Cell cycle	0.5068	0.21188
BT-20	AZD7762	0.31623	CHK1/2	Cell cycle	0.9454	0.07692