Breast Cancer Profiling Project, Drug Sensitivity phase I: Fixed-cell GR measures of 35 breast cell lines to 34 small molecule perturbagens from library plate I. Dataset 1 of 2: Normalized growth rate inhibition values - Dataset (ID:20343)

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Cell Small Molecule Small Mol Concentration (uM) Primary Target Pathway Mean Normalized Growth Rate Inhibition Value Increased Fraction Dead
MCF 10A Cediranib
0.001
VEGFR/cKIT
RTK
 1.0032 0.00120
MCF 10A Cediranib
0.0031623
VEGFR/cKIT
RTK
 1.0035 -0.00027
MCF 10A Cediranib
0.01
VEGFR/cKIT
RTK
 1.0016 -0.00009
MCF 10A Cediranib
0.031623
VEGFR/cKIT
RTK
 1.0136 0.00006
MCF 10A Cediranib
0.1
VEGFR/cKIT
RTK
 1.0093 -0.00083
MCF 10A Cediranib
0.31623
VEGFR/cKIT
RTK
 1.0087 -0.00055
MCF 10A Cediranib
1.0
VEGFR/cKIT
RTK
 1.0068 0.00027
MCF 10A Cediranib
3.1623
VEGFR/cKIT
RTK
 0.9680 -0.00217
MCF 10A Cediranib
10.0
VEGFR/cKIT
RTK
 0.4781 0.01325
MCF 10A Cabozantinib
0.001
VEGFR2/MET
RTK
 1.0043 0.00034
MCF 10A Cabozantinib
0.0031623
VEGFR2/MET
RTK
 0.9977 0.00051
MCF 10A Cabozantinib
0.01
VEGFR2/MET
RTK
 1.0116 0.00015
MCF 10A Cabozantinib
0.031623
VEGFR2/MET
RTK
 1.0213 0.00255
MCF 10A Cabozantinib
0.1
VEGFR2/MET
RTK
 1.0347 0.00414
MCF 10A Cabozantinib
0.31623
VEGFR2/MET
RTK
 1.0316 0.00638
MCF 10A Cabozantinib
1.0
VEGFR2/MET
RTK
 1.0476 0.00809
MCF 10A Cabozantinib
3.1623
VEGFR2/MET
RTK
 1.0233 0.00799
MCF 10A Cabozantinib
10.0
VEGFR2/MET
RTK
 0.8434 0.00621
MCF7 Abemaciclib
0.001
CDK4/6
Cell cycle
 0.8973 0.00124
MCF7 Abemaciclib
0.0031623
CDK4/6
Cell cycle
 0.7894 0.00211
MCF7 Abemaciclib
0.01
CDK4/6
Cell cycle
 0.5295 0.01381
MCF7 Abemaciclib
0.031623
CDK4/6
Cell cycle
 0.3537 0.02589
MCF7 Abemaciclib
0.1
CDK4/6
Cell cycle
 0.2506 0.03087
MCF7 Abemaciclib
0.31623
CDK4/6
Cell cycle
 0.2236 0.03533
MCF7 Abemaciclib
1.0
CDK4/6
Cell cycle
 0.1092 0.05999