Breast Cancer Profiling Project, Drug Sensitivity phase I: Fixed-cell GR measures of 35 breast cell lines to 34 small molecule perturbagens from library plate I. Dataset 1 of 2: Normalized growth rate inhibition values - Dataset (ID:20343)

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Cell Small Molecule Small Mol Concentration (uM) Primary Target Pathway Mean Normalized Growth Rate Inhibition Value Increased Fraction Dead
T47D TGX221
0.031623
PI3Kb
PI3K/mTOR
 1.0945 -0.00185
T47D TGX221
0.1
PI3Kb
PI3K/mTOR
 1.0327 -0.00036
T47D TGX221
0.31623
PI3Kb
PI3K/mTOR
 1.0372 -0.00182
T47D TGX221
1.0
PI3Kb
PI3K/mTOR
 0.9841 0.00051
T47D TGX221
3.1623
PI3Kb
PI3K/mTOR
 0.9245 -0.00077
T47D TGX221
10.0
PI3Kb
PI3K/mTOR
 0.7986 0.00168
T47D Torin2
0.0001
mTOR/ATM/ATR
PI3K/mTOR
 1.0779 -0.00180
T47D Torin2
0.00031623
mTOR/ATM/ATR
PI3K/mTOR
 1.0340 -0.00019
T47D Torin2
0.001
mTOR/ATM/ATR
PI3K/mTOR
 0.9543 -0.00159
T47D Torin2
0.0031623
mTOR/ATM/ATR
PI3K/mTOR
 0.6738 0.00311
T47D Torin2
0.01
mTOR/ATM/ATR
PI3K/mTOR
 0.3592 0.01283
T47D Torin2
0.031623
mTOR/ATM/ATR
PI3K/mTOR
 0.1112 0.02794
T47D Torin2
0.1
mTOR/ATM/ATR
PI3K/mTOR
 0.0792 0.03630
T47D Torin2
0.31623
mTOR/ATM/ATR
PI3K/mTOR
 0.0674 0.04879
T47D Torin2
1.0
mTOR/ATM/ATR
PI3K/mTOR
 0.0099 0.07041
T47D Everolimus
0.001
mTOR1
PI3K/mTOR
 0.4754 0.00865
T47D Everolimus
0.0031623
mTOR1
PI3K/mTOR
 0.3963 0.01398
T47D Everolimus
0.01
mTOR1
PI3K/mTOR
 0.4114 0.01119
T47D Everolimus
0.031623
mTOR1
PI3K/mTOR
 0.3939 0.01335
T47D Everolimus
0.1
mTOR1
PI3K/mTOR
 0.4198 0.02159
T47D Everolimus
0.31623
mTOR1
PI3K/mTOR
 0.3554 0.01646
T47D Everolimus
1.0
mTOR1
PI3K/mTOR
 0.3599 0.01312
T47D Everolimus
3.1623
mTOR1
PI3K/mTOR
 0.3515 0.01517
T47D Everolimus
10.0
mTOR1
PI3K/mTOR
 0.2975 0.02128
T47D INK-128
0.00031623
mTORC1/2
PI3K/mTOR
 1.0271 0.00098