Breast Cancer Profiling Project, Drug Sensitivity phase I: Fixed-cell GR measures of 35 breast cell lines to 34 small molecule perturbagens from library plate I. Dataset 1 of 2: Normalized growth rate inhibition values - Dataset (ID:20343)

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Cell Small Molecule Small Mol Concentration (uM) Primary Target Pathway Mean Normalized Growth Rate Inhibition Value Increased Fraction Dead
SUM149PT Olaparib
0.1
PARP
Misc
 0.8640 0.01847
SUM149PT Olaparib
0.31623
PARP
Misc
 0.8639 0.02885
SUM149PT Olaparib
1.0
PARP
Misc
 0.7813 0.04644
SUM149PT Olaparib
3.1623
PARP
Misc
 0.6095 0.09427
SUM149PT Olaparib
10.0
PARP
Misc
 0.2077 0.30872
SUM149PT Bleomycin
0.0010833
Radiation
Misc
 0.9838 0.00067
SUM149PT Bleomycin
0.0033333
Radiation
Misc
 0.9497 0.01062
SUM149PT Bleomycin
0.01
Radiation
Misc
 0.8325 0.04569
SUM149PT Bleomycin
0.031667
Radiation
Misc
 0.5216 0.16694
SUM149PT Bleomycin
0.1
Radiation
Misc
 0.2111 0.31172
SUM149PT Bleomycin
0.31623
Radiation
Misc
 -0.0007 0.34947
SUM149PT Bleomycin
1.0
Radiation
Misc
 -0.0941 0.40485
SUM149PT Bleomycin
3.1623
Radiation
Misc
 -0.1764 0.52166
SUM149PT Bleomycin
10.0
Radiation
Misc
 -0.3154 0.67673
SUM149PT Ipatasertib
0.001
AKT
PI3K/mTOR
 1.0049 0.00166
SUM149PT Ipatasertib
0.0031623
AKT
PI3K/mTOR
 1.0126 0.00506
SUM149PT Ipatasertib
0.01
AKT
PI3K/mTOR
 1.0045 -0.00033
SUM149PT Ipatasertib
0.031623
AKT
PI3K/mTOR
 1.0010 0.00609
SUM149PT Ipatasertib
0.1
AKT
PI3K/mTOR
 0.9930 -0.00041
SUM149PT Ipatasertib
0.31623
AKT
PI3K/mTOR
 0.9148 0.00209
SUM149PT Ipatasertib
1.0
AKT
PI3K/mTOR
 0.8148 -0.00049
SUM149PT Ipatasertib
3.1623
AKT
PI3K/mTOR
 0.6019 0.00598
SUM149PT Ipatasertib
10.0
AKT
PI3K/mTOR
 0.2929 0.04056
SUM149PT Alpelisib
0.001
PI3Ka
PI3K/mTOR
 0.9644 0.00434
SUM149PT Alpelisib
0.0031623
PI3Ka
PI3K/mTOR
 0.9803 0.00670