LINCS MCF 10A Common Project: Rolling-time-point sensitivity measures of the MCF 10A breast cell line to 8 small molecule perturbagens. Dataset 15 of 15: Time-dependent dose-response metrics for biological replicate 3. - Dataset (ID:20323)

Data Columns

  • 10 Data Columns
Name Description Display Name Data Type Unit Precision Readout Type Replicate Comments
timeIntervalHr
Total time from start to end of rolling window (in hr; averaged across technical replicates)
Time Interval (hr) Numeric hr 1
timePointHr
End time point of rolling window (in hr; averaged across technical replicates)
Time Point (hr) Numeric hr 2
gRmax
Normalized growth inhibition rate at the highest tested concentration
GRmax Numeric 4
gRAOC
Integral of GR(c) over the range of concentrations tested
GR_AOC Numeric 4
gRHillCoefficient
Maximal slope of the dose-response curve
GR Hill Coefficient Numeric 4
gRinf
Asymptotic value (concentration = infinity) for the sigmoidal curve fit to the dose-response data
GRinf Numeric 4
cell
Cell reagent
Cell cell
gEC50
Small molecule concentration in uM that results in 50% efficacy
GEC50 Text
gR50
Small molecule concentration in uM at which GR(c)=0.5
GR50 Text
smallMolecule
Small molecule perturbagen
Small Molecule small_molecule
  • 10 Data Columns