LINCS MCF 10A Common Project: Rolling-time-point sensitivity measures of the MCF 10A breast cell line to 8 small molecule perturbagens. Dataset 9 of 15: End-point dose-response metrics for biological replicate 3. - Dataset (ID:20317)

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Cell Small Molecule Time Point (hr) GR50 GEC50 GRmax GRinf GR Hill Coefficient GR_AOC
MCF 10A-H2B-mCherry Taxol 84
0.0009
0.0012
-0.3444 -0.2890 1.3812 0.8153
MCF 10A-H2B-mCherry Taxol 72
0.001
0.0013
-0.3180 -0.2585 1.4036 0.7880
MCF 10A-H2B-mCherry Taxol 60
0.0011
0.0014
-0.3195 -0.2487 1.3756 0.7703
MCF 10A-H2B-mCherry Taxol 48
0.0013
0.0019
-0.3312 -0.2815 1.1758 0.7519
MCF 10A-H2B-mCherry Taxol 36
0.0017
0.0028
-0.3238 -0.3277 0.9300 0.7159
MCF 10A-H2B-mCherry Taxol 12
0.0017
2.6985
0.1492 -1.0000 0.1490 0.5622
MCF 10A-H2B-mCherry Taxol 24
0.002
0.0084
-0.2083 -0.5081 0.4902 0.6573
MCF 10A-H2B-mCherry Trametinib 72
0.0717
0.0063
0.3482 0.3285 0.4390 0.3784
MCF 10A-H2B-mCherry Neratinib 24
0.0809
0.0088
0.2144 0.3494 0.5423 0.4143
MCF 10A-H2B-mCherry Trametinib 84
0.1232
0.0231
0.3664 0.2222 0.3508 0.3587
MCF 10A-H2B-mCherry Neratinib 36
0.1462
0.1855
0.2073 -0.0474 0.3804 0.3953
MCF 10A-H2B-mCherry Neratinib 48
0.1895
4.5797
0.0307 -1.0000 0.3449 0.3845
MCF 10A-H2B-mCherry Neratinib 60
0.2207
3.2708
-0.0756 -1.0000 0.4075 0.3689
MCF 10A-H2B-mCherry Neratinib 72
0.246
2.6692
-0.1124 -1.0000 0.4607 0.3588
MCF 10A-H2B-mCherry Neratinib 84
0.2629
2.4045
-0.1966 -1.0000 0.4964 0.3709
MCF 10A-H2B-mCherry Trametinib 60
0.2951
0.0015
0.5078 0.4730 0.5502 0.3764
MCF 10A-H2B-mCherry Etoposide 84
0.3533
0.6359
0.1344 -0.1515 0.4501 0.4060
MCF 10A-H2B-mCherry Vorinostat 24
0.4754
1.7724
-0.0276 -0.4821 0.5130 0.4423
MCF 10A-H2B-mCherry Vorinostat 36
0.554
0.9298
-0.0652 -0.2551 0.7961 0.4258
MCF 10A-H2B-mCherry Etoposide 72
0.5612
1.2244
0.1419 -0.2015 0.4341 0.3610
MCF 10A-H2B-mCherry Dasatinib 84
0.5642
58.6317
-0.0543 -1.0000 0.2366 0.3960
MCF 10A-H2B-mCherry Vorinostat 48
0.6114
0.9444
-0.0821 -0.2429 0.9107 0.4110
MCF 10A-H2B-mCherry Vorinostat 60
0.7223
1.0618
-0.0810 -0.2268 0.9711 0.3866
MCF 10A-H2B-mCherry Vorinostat 72
0.8282
1.127
-0.0873 -0.2023 1.1031 0.3632
MCF 10A-H2B-mCherry Etoposide 60
0.847
16.3367
0.1412 -0.8621 0.3387 0.3416
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