Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 2 of 4: Calculated dose-response metrics. - Dataset - HMS LINCS Database

Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 2 of 4: Calculated dose-response metrics. - Dataset (ID:20269)

Download: Excel (XLSX), Comma-separated (CSV)

<<<<

Select the entities to show:

Small molecules	Cells	Antibodies

<
<<
Previous
Page 1 of 370
Next
>>
>
1 to 25 of 9248 records
per page:

Cell	Clinical Subtype	Transcriptional Subtype	Small Molecule	Perturbagen Target	Perturbagen Class	Biological Replicate ID	Conc Unit	GR50	GEC50	GRmax	GRinf	GR Hill Coefficient	GR_AOC	GR r2	Nominal Division Rate
BT-474	HER2amp	Luminal	Sigma A6730	AKT	AKT	12056.158	uM	0.72952	3.1890	-0.8607	-1.0000	0.7448	0.5557	0.9726	0.9929
BT-483	HR+	Luminal	Sigma A6730	AKT	AKT	11855.158	uM	0.14373	3.28620	-0.6376	-1.0000	0.3511	0.6088	0.9430	0.6941
AU565	HER2amp	Luminal	Triciribine	AKT	AKT	5901.074	uM	0.02039	0.16902	-0.8539	-0.9086	0.4897	0.7799	0.9864	1.8718
BT-474	HER2amp	Luminal	Sigma A6730	AKT	AKT	12291.165	uM	0.08918	0.66991	-0.9980	-1.0000	0.5448	0.8274	0.8520	0.5602
BT-474	HER2amp	Luminal	Triciribine	AKT	AKT	5906.074	uM	0.01550	0.02634	-0.2986	-0.2004	0.6357	0.6325	0.9018	0.6442
BT-474	HER2amp	Luminal	Triciribine	AKT	AKT	5905.074	uM	0.07957	0.15194	-0.2667	-0.3062	0.7386	0.5707	0.9369	0.8648
AU565	HER2amp	Luminal	Sigma A6730	AKT	AKT	10880.153	uM	2.73280	8.96010	-0.8497	-1.0000	0.9252	0.4067	0.9538	1.6896
AU565	HER2amp	Luminal	Triciribine	AKT	AKT	5900.074	uM	0.07721	0.15941	-0.5051	-0.5223	0.9865	0.6448	0.9219	2.4189
BT-20	TNBC	Basal A	Sigma A6730	AKT	AKT	11854.158	uM	11.36580	18.74490	-0.9093	-1.0000	2.1958	0.2543	0.9867	1.3776
BT-20	TNBC	Basal A	Triciribine	AKT	AKT	5902.074	uM	1.97260	8.09640	-0.2309	-0.7316	0.6384	0.2588	0.9950	1.2939
BT-474	HER2amp	Luminal	Sigma A6730	AKT	AKT	12178.158	uM	1.57950	4.28540	-0.8896	-1.0000	1.1007	0.4947	0.9798	0.7379
600MPE	HR+	Luminal	Sigma A6730	AKT	AKT	12224.165	uM	6.5660	13.29760	-0.9371	-1.0000	1.5568	0.3611	0.9610	0.9714
600MPE	HR+	Luminal	Triciribine	AKT	AKT	5898.074	uM	0.57767	3.96870	-0.0423	-0.5354	0.3777	0.3788	0.9668	0.7134
600MPE	HR+	Luminal	Triciribine	AKT	AKT	5899.074	uM	0.63713	68.74810	0.0341	-1.0000	0.2347	0.3748	0.9523	0.8860
184A1	NM	Basal	Triciribine	AKT	AKT	5895.074	uM	0.08792	0.23992	-0.7686	-0.7129	0.8827	0.6419	0.9956	1.1218
184B5	NM	Basal	Triciribine	AKT	AKT	5897.074	uM	0.14593	0.26720	-0.6810	-0.6218	1.3360	0.6294	0.9925	1.2824
184B5	NM	Basal	Triciribine	AKT	AKT	5896.074	uM	0.08583	0.37083	-0.6648	-0.7348	0.6178	0.6095	0.9963	1.4124
184A1	NM	Basal	Sigma A6730	AKT	AKT	12509.165	uM	3.14240	13.05610	-0.6553	-1.0000	0.7714	0.3161	0.9885	1.5022
184A1	NM	Basal	Triciribine	AKT	AKT	5894.074	uM	0.10268	0.28489	-0.6622	-0.6112	0.7825	0.5807	0.9866	1.4541
BT-20	TNBC	Basal A	Sigma A6730	AKT	AKT	10581.141	uM	5.68520	11.73980	-0.9996	-1.0000	1.5151	0.3224	0.9843	0.6310
BT-20	TNBC	Basal A	Triciribine	AKT	AKT	5904.074	uM	0.56544	0.77026	-0.2190	-0.1688	0.9408	0.3518	0.9569	0.9654
BT-20	TNBC	Basal A	Triciribine	AKT	AKT	5903.074	uM	1.02210	3.13290	-0.3635	-0.6039	0.7071	0.3330	0.9862	1.0729
184B5	NM	Basal	Sigma A6730	AKT	AKT	12566.165	uM	2.97380	8.22950	-0.8497	-1.0000	1.0793	0.4028	0.9697	1.7248
BT-483	HR+	Luminal	Triciribine	AKT	AKT	5908.074	uM	0.01754	0.14176	-0.3535	-0.5337	0.3476	0.6743	0.9586	0.5224
BT-483	HR+	Luminal	Sigma A6730	AKT	AKT	10696.153	uM	1.1750	2.84060	-0.6524	-0.6846	0.9772	0.4348	0.9803	0.5484

<
<<
Previous
Page 1 of 370
Next
>>
>
1 to 25 of 9248 records
per page:

HMS LINCS Project

Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 2 of 4: Calculated dose-response metrics. - Dataset (ID:20269)