Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MDA-MB-453 | TNBC | Luminal | Erlotinib | EGFR | ErbB | 33.3 | uM | 7516.092 | 0.8229 | 0.6762 | 1.1035 | |
| MDA-MB-453 | TNBC | Luminal | Erlotinib | EGFR | ErbB | 0.000171 | uM | 7517.091 | 0.9461 | 0.9300 | 1.5552 | |
| MDA-MB-453 | TNBC | Luminal | Erlotinib | EGFR | ErbB | 0.000853 | uM | 7517.091 | 0.7741 | 0.6964 | 1.5552 | |
| MDA-MB-453 | TNBC | Luminal | Erlotinib | EGFR | ErbB | 0.00427 | uM | 7517.091 | 0.9066 | 0.8778 | 1.5552 | |
| MDA-MB-453 | TNBC | Luminal | Erlotinib | EGFR | ErbB | 0.0213 | uM | 7517.091 | 0.8743 | 0.8345 | 1.5552 | |
| MDA-MB-453 | TNBC | Luminal | Erlotinib | EGFR | ErbB | 0.107 | uM | 7517.091 | 0.9476 | 0.9320 | 1.5552 | |
| MDA-MB-453 | TNBC | Luminal | Erlotinib | EGFR | ErbB | 0.533 | uM | 7517.091 | 0.9490 | 0.9338 | 1.5552 | |
| MDA-MB-453 | TNBC | Luminal | Erlotinib | EGFR | ErbB | 2.67 | uM | 7517.091 | 0.9296 | 0.9083 | 1.5552 | |
| MDA-MB-453 | TNBC | Luminal | Erlotinib | EGFR | ErbB | 13.3 | uM | 7517.091 | 0.8141 | 0.7522 | 1.5552 | |
| MDA-MB-453 | TNBC | Luminal | Erlotinib | EGFR | ErbB | 66.7 | uM | 7517.091 | 0.6386 | 0.4989 | 1.5552 | |
| MDA-MB-453 | TNBC | Luminal | Erlotinib | EGFR | ErbB | 0.000171 | uM | 7518.091 | 0.9427 | 0.9283 | 1.6174 | |
| MDA-MB-453 | TNBC | Luminal | Erlotinib | EGFR | ErbB | 0.000853 | uM | 7518.091 | 1.0030 | 1.0037 | 1.6174 | |
| MDA-MB-453 | TNBC | Luminal | Erlotinib | EGFR | ErbB | 0.00427 | uM | 7518.091 | 0.9449 | 0.9311 | 1.6174 | |
| MDA-MB-453 | TNBC | Luminal | Erlotinib | EGFR | ErbB | 0.0213 | uM | 7518.091 | 0.9952 | 0.9941 | 1.6174 | |
| MDA-MB-453 | TNBC | Luminal | Erlotinib | EGFR | ErbB | 0.107 | uM | 7518.091 | 0.9290 | 0.9110 | 1.6174 | |
| MDA-MB-453 | TNBC | Luminal | Erlotinib | EGFR | ErbB | 0.533 | uM | 7518.091 | 0.9815 | 0.9771 | 1.6174 | |
| MDA-MB-453 | TNBC | Luminal | Erlotinib | EGFR | ErbB | 2.67 | uM | 7518.091 | 0.9364 | 0.9204 | 1.6174 | |
| MDA-MB-453 | TNBC | Luminal | Erlotinib | EGFR | ErbB | 13.3 | uM | 7518.091 | 0.8788 | 0.8465 | 1.6174 | |
| MDA-MB-453 | TNBC | Luminal | Erlotinib | EGFR | ErbB | 66.7 | uM | 7518.091 | 0.6948 | 0.5968 | 1.6174 | |
| MX1 | Unknown | Unknown | Erlotinib | EGFR | ErbB | 0.000171 | uM | 7523.091 | 0.9772 | 0.9508 | 0.9283 | |
| MX1 | Unknown | Unknown | Erlotinib | EGFR | ErbB | 0.000853 | uM | 7523.091 | 0.9263 | 0.8418 | 0.9283 | |
| MX1 | Unknown | Unknown | Erlotinib | EGFR | ErbB | 0.00427 | uM | 7523.091 | 0.9350 | 0.8604 | 0.9283 | |
| MX1 | Unknown | Unknown | Erlotinib | EGFR | ErbB | 0.0213 | uM | 7523.091 | 0.9329 | 0.8558 | 0.9283 | |
| MX1 | Unknown | Unknown | Erlotinib | EGFR | ErbB | 0.107 | uM | 7523.091 | 0.9593 | 0.9125 | 0.9283 | |
| MX1 | Unknown | Unknown | Erlotinib | EGFR | ErbB | 0.533 | uM | 7523.091 | 0.8951 | 0.7749 | 0.9283 |