Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC1428 | HR+ | Luminal | Erlotinib | EGFR | ErbB | 0.0213 | uM | 7441.09 | 1.0534 | 1.1470 | 0.7331 | |
| HCC1428 | HR+ | Luminal | Erlotinib | EGFR | ErbB | 0.107 | uM | 7441.09 | 0.9804 | 0.9466 | 0.7331 | |
| HCC1428 | HR+ | Luminal | Erlotinib | EGFR | ErbB | 0.533 | uM | 7441.09 | 1.0173 | 1.0473 | 0.7331 | |
| HCC1428 | HR+ | Luminal | Erlotinib | EGFR | ErbB | 2.67 | uM | 7441.09 | 1.0467 | 1.1286 | 0.7331 | |
| HCC1428 | HR+ | Luminal | Erlotinib | EGFR | ErbB | 13.3 | uM | 7441.09 | 0.9317 | 0.8161 | 0.7331 | |
| HCC1428 | HR+ | Luminal | Erlotinib | EGFR | ErbB | 66.7 | uM | 7441.09 | 0.7963 | 0.4658 | 0.7331 | |
| HCC1428 | HR+ | Luminal | Erlotinib | EGFR | ErbB | 0.0000853 | uM | 7442.092 | 1.0277 | 1.0710 | 0.7831 | |
| HCC1428 | HR+ | Luminal | Erlotinib | EGFR | ErbB | 0.000427 | uM | 7442.092 | 0.9999 | 0.9999 | 0.7831 | |
| HCC1428 | HR+ | Luminal | Erlotinib | EGFR | ErbB | 0.00213 | uM | 7442.092 | 1.0340 | 1.0873 | 0.7831 | |
| HCC1428 | HR+ | Luminal | Erlotinib | EGFR | ErbB | 0.0107 | uM | 7442.092 | 0.9883 | 0.9703 | 0.7831 | |
| HCC1428 | HR+ | Luminal | Erlotinib | EGFR | ErbB | 0.0533 | uM | 7442.092 | 1.0118 | 1.0301 | 0.7831 | |
| HCC1428 | HR+ | Luminal | Erlotinib | EGFR | ErbB | 0.267 | uM | 7442.092 | 0.9944 | 0.9856 | 0.7831 | |
| HCC1428 | HR+ | Luminal | Erlotinib | EGFR | ErbB | 1.33 | uM | 7442.092 | 0.9779 | 0.9437 | 0.7831 | |
| HCC1428 | HR+ | Luminal | Erlotinib | EGFR | ErbB | 6.67 | uM | 7442.092 | 0.9535 | 0.8819 | 0.7831 | |
| HCC1428 | HR+ | Luminal | Erlotinib | EGFR | ErbB | 33.3 | uM | 7442.092 | 0.6688 | 0.1965 | 0.7831 | |
| HCC1428 | HR+ | Luminal | Erlotinib | EGFR | ErbB | 0.000171 | uM | 7443.09 | 1.0150 | 1.0318 | 0.9451 | |
| HCC1428 | HR+ | Luminal | Erlotinib | EGFR | ErbB | 0.000853 | uM | 7443.09 | 0.9837 | 0.9655 | 0.9451 | |
| HCC1428 | HR+ | Luminal | Erlotinib | EGFR | ErbB | 0.00427 | uM | 7443.09 | 0.9976 | 0.9950 | 0.9451 | |
| HCC1428 | HR+ | Luminal | Erlotinib | EGFR | ErbB | 0.0213 | uM | 7443.09 | 1.0618 | 1.1309 | 0.9451 | |
| HCC1428 | HR+ | Luminal | Erlotinib | EGFR | ErbB | 0.107 | uM | 7443.09 | 0.9725 | 0.9418 | 0.9451 | |
| HCC1428 | HR+ | Luminal | Erlotinib | EGFR | ErbB | 0.533 | uM | 7443.09 | 0.9822 | 0.9622 | 0.9451 | |
| HCC1428 | HR+ | Luminal | Erlotinib | EGFR | ErbB | 2.67 | uM | 7443.09 | 1.0040 | 1.0084 | 0.9451 | |
| HCC1428 | HR+ | Luminal | Erlotinib | EGFR | ErbB | 13.3 | uM | 7443.09 | 0.8448 | 0.6732 | 0.9451 | |
| HCC1428 | HR+ | Luminal | Erlotinib | EGFR | ErbB | 66.7 | uM | 7443.09 | 0.6475 | 0.2626 | 0.9451 | |
| HCC1428 | HR+ | Luminal | Erlotinib | EGFR | ErbB | 0.000171 | uM | 7444.091 | 1.0240 | 1.0548 | 0.8764 |