Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AU565 | HER2amp | Luminal | Docetaxel | TUBB | TUBB | 0.0032 | uM | 13030.002 | 0.2878 | -0.7723 | 0.5732 | |
| AU565 | HER2amp | Luminal | Docetaxel | TUBB | TUBB | 0.016 | uM | 13030.002 | 0.2052 | -0.8738 | 0.5732 | |
| AU565 | HER2amp | Luminal | Docetaxel | TUBB | TUBB | 0.08 | uM | 13030.002 | 0.1999 | -0.8794 | 0.5732 | |
| AU565 | HER2amp | Luminal | Docetaxel | TUBB | TUBB | 0.4 | uM | 13030.002 | 0.2362 | -0.8388 | 0.5732 | |
| AU565 | HER2amp | Luminal | Docetaxel | TUBB | TUBB | 2 | uM | 13030.002 | 0.1686 | -0.9104 | 0.5732 | |
| AU565 | HER2amp | Luminal | Docetaxel | TUBB | TUBB | 10 | uM | 13030.002 | 0.1980 | -0.8814 | 0.5732 | |
| BT-474 | HER2amp | Luminal | Docetaxel | TUBB | TUBB | 0.0000256 | uM | 9157.002 | 0.9707 | 0.9370 | 0.9306 | |
| BT-474 | HER2amp | Luminal | Docetaxel | TUBB | TUBB | 0.000128 | uM | 9157.002 | 1.0055 | 1.0118 | 0.9306 | |
| BT-474 | HER2amp | Luminal | Docetaxel | TUBB | TUBB | 0.00064 | uM | 9157.002 | 1.0135 | 1.0290 | 0.9306 | |
| BT-474 | HER2amp | Luminal | Docetaxel | TUBB | TUBB | 0.0032 | uM | 9157.002 | 0.8782 | 0.7396 | 0.9306 | |
| BT-474 | HER2amp | Luminal | Docetaxel | TUBB | TUBB | 0.016 | uM | 9157.002 | 0.5978 | 0.1506 | 0.9306 | |
| BT-474 | HER2amp | Luminal | Docetaxel | TUBB | TUBB | 0.08 | uM | 9157.002 | 0.4712 | -0.1090 | 0.9306 | |
| BT-474 | HER2amp | Luminal | Docetaxel | TUBB | TUBB | 0.4 | uM | 9157.002 | 0.4734 | -0.1046 | 0.9306 | |
| BT-474 | HER2amp | Luminal | Docetaxel | TUBB | TUBB | 2 | uM | 9157.002 | 0.4714 | -0.1086 | 0.9306 | |
| BT-474 | HER2amp | Luminal | Docetaxel | TUBB | TUBB | 10 | uM | 9157.002 | 0.4709 | -0.1096 | 0.9306 | |
| BT-474 | HER2amp | Luminal | Docetaxel | TUBB | TUBB | 0.0000256 | uM | 9158.002 | 1.1164 | 1.5840 | 0.4298 | |
| BT-474 | HER2amp | Luminal | Docetaxel | TUBB | TUBB | 0.000128 | uM | 9158.002 | 1.1386 | 1.7052 | 0.4298 | |
| BT-474 | HER2amp | Luminal | Docetaxel | TUBB | TUBB | 0.00064 | uM | 9158.002 | 1.1392 | 1.7084 | 0.4298 | |
| BT-474 | HER2amp | Luminal | Docetaxel | TUBB | TUBB | 0.0032 | uM | 9158.002 | 0.9820 | 0.9173 | 0.4298 | |
| BT-474 | HER2amp | Luminal | Docetaxel | TUBB | TUBB | 0.016 | uM | 9158.002 | 0.5894 | -0.4154 | 0.4298 | |
| BT-474 | HER2amp | Luminal | Docetaxel | TUBB | TUBB | 0.08 | uM | 9158.002 | 0.4367 | -0.7090 | 0.4298 | |
| BT-474 | HER2amp | Luminal | Docetaxel | TUBB | TUBB | 0.4 | uM | 9158.002 | 0.4060 | -0.7545 | 0.4298 | |
| BT-474 | HER2amp | Luminal | Docetaxel | TUBB | TUBB | 2 | uM | 9158.002 | 0.4727 | -0.6502 | 0.4298 | |
| BT-474 | HER2amp | Luminal | Docetaxel | TUBB | TUBB | 10 | uM | 9158.002 | 0.4310 | -0.7179 | 0.4298 | |
| BT-474 | HER2amp | Luminal | Docetaxel | TUBB | TUBB | 0.0000256 | uM | 9163.002 | 1.0207 | 1.0695 | 0.6004 |