Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
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184A1 | NM | Basal | Docetaxel | TUBB | TUBB | 2 | uM | 12684.002 | 0.6821 | 0.5562 | 1.5245 | |
184A1 | NM | Basal | Docetaxel | TUBB | TUBB | 10 | uM | 12684.002 | 0.6698 | 0.5376 | 1.5245 | |
184B5 | NM | Basal | Docetaxel | TUBB | TUBB | 0.0000256 | uM | 9095.002 | 1.0257 | 1.0484 | 1.0607 | |
184B5 | NM | Basal | Docetaxel | TUBB | TUBB | 0.000128 | uM | 9095.002 | 1.0406 | 1.0765 | 1.0607 | |
184B5 | NM | Basal | Docetaxel | TUBB | TUBB | 0.00064 | uM | 9095.002 | 0.9755 | 0.9537 | 1.0607 | |
184B5 | NM | Basal | Docetaxel | TUBB | TUBB | 0.0032 | uM | 9095.002 | 0.7778 | 0.5782 | 1.0607 | |
184B5 | NM | Basal | Docetaxel | TUBB | TUBB | 0.016 | uM | 9095.002 | 0.6832 | 0.3966 | 1.0607 | |
184B5 | NM | Basal | Docetaxel | TUBB | TUBB | 0.08 | uM | 9095.002 | 0.6525 | 0.3373 | 1.0607 | |
184B5 | NM | Basal | Docetaxel | TUBB | TUBB | 0.4 | uM | 9095.002 | 0.6297 | 0.2932 | 1.0607 | |
184B5 | NM | Basal | Docetaxel | TUBB | TUBB | 2 | uM | 9095.002 | 0.7446 | 0.5146 | 1.0607 | |
184B5 | NM | Basal | Docetaxel | TUBB | TUBB | 10 | uM | 9095.002 | 0.6938 | 0.4170 | 1.0607 | |
184B5 | NM | Basal | Docetaxel | TUBB | TUBB | 0.0000256 | uM | 12979.002 | 0.8682 | 0.7966 | 1.3178 | |
184B5 | NM | Basal | Docetaxel | TUBB | TUBB | 0.000128 | uM | 12979.002 | 1.2203 | 1.3261 | 1.3178 | |
184B5 | NM | Basal | Docetaxel | TUBB | TUBB | 0.00064 | uM | 12979.002 | 0.8396 | 0.7515 | 1.3178 | |
184B5 | NM | Basal | Docetaxel | TUBB | TUBB | 0.0032 | uM | 12979.002 | 1.0834 | 1.1254 | 1.3178 | |
184B5 | NM | Basal | Docetaxel | TUBB | TUBB | 0.016 | uM | 12979.002 | 0.8258 | 0.7297 | 1.3178 | |
184B5 | NM | Basal | Docetaxel | TUBB | TUBB | 0.08 | uM | 12979.002 | 0.8207 | 0.7215 | 1.3178 | |
184B5 | NM | Basal | Docetaxel | TUBB | TUBB | 0.4 | uM | 12979.002 | 0.8483 | 0.7653 | 1.3178 | |
184B5 | NM | Basal | Docetaxel | TUBB | TUBB | 2 | uM | 12979.002 | 0.8956 | 0.8395 | 1.3178 | |
184B5 | NM | Basal | Docetaxel | TUBB | TUBB | 10 | uM | 12979.002 | 0.8210 | 0.7220 | 1.3178 | |
600MPE | HR+ | Luminal | Docetaxel | TUBB | TUBB | 0.0000256 | uM | 9118.002 | 1.0333 | 1.0674 | 0.9880 | |
600MPE | HR+ | Luminal | Docetaxel | TUBB | TUBB | 0.000128 | uM | 9118.002 | 1.1219 | 1.2468 | 0.9880 | |
600MPE | HR+ | Luminal | Docetaxel | TUBB | TUBB | 0.00064 | uM | 9118.002 | 0.9861 | 0.9719 | 0.9880 | |
600MPE | HR+ | Luminal | Docetaxel | TUBB | TUBB | 0.0032 | uM | 9118.002 | 0.9942 | 0.9882 | 0.9880 | |
600MPE | HR+ | Luminal | Docetaxel | TUBB | TUBB | 0.016 | uM | 9118.002 | 0.9105 | 0.8190 | 0.9880 |