Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MDA-MB-175-VII | HR+ | Luminal | 17-AAG | HSP90 | HSP90 | 0.00128 | uM | 7885.05 | 0.9946 | 0.9833 | 0.6518 | |
| MDA-MB-175-VII | HR+ | Luminal | 17-AAG | HSP90 | HSP90 | 0.0064 | uM | 7885.05 | 0.9314 | 0.7934 | 0.6518 | |
| MDA-MB-175-VII | HR+ | Luminal | 17-AAG | HSP90 | HSP90 | 0.032 | uM | 7885.05 | 0.6786 | 0.1032 | 0.6518 | |
| MDA-MB-175-VII | HR+ | Luminal | 17-AAG | HSP90 | HSP90 | 0.16 | uM | 7885.05 | 0.3816 | -0.5439 | 0.6518 | |
| MDA-MB-175-VII | HR+ | Luminal | 17-AAG | HSP90 | HSP90 | 0.8 | uM | 7885.05 | 0.4088 | -0.4931 | 0.6518 | |
| MDA-MB-175-VII | HR+ | Luminal | 17-AAG | HSP90 | HSP90 | 4 | uM | 7885.05 | 0.3472 | -0.6053 | 0.6518 | |
| MDA-MB-175-VII | HR+ | Luminal | 17-AAG | HSP90 | HSP90 | 20 | uM | 7885.05 | 0.2709 | -0.7304 | 0.6518 | |
| MDA-MB-175-VII | HR+ | Luminal | 17-AAG | HSP90 | HSP90 | 100 | uM | 7885.05 | 0.1696 | -0.8685 | 0.6518 | |
| MDA-MB-175-VII | HR+ | Luminal | 17-AAG | HSP90 | HSP90 | 0.000256 | uM | 7886.04 | 0.9634 | 0.9064 | 0.7771 | |
| MDA-MB-175-VII | HR+ | Luminal | 17-AAG | HSP90 | HSP90 | 0.00128 | uM | 7886.04 | 0.9440 | 0.8569 | 0.7771 | |
| MDA-MB-175-VII | HR+ | Luminal | 17-AAG | HSP90 | HSP90 | 0.0064 | uM | 7886.04 | 1.0122 | 1.0315 | 0.7771 | |
| MDA-MB-175-VII | HR+ | Luminal | 17-AAG | HSP90 | HSP90 | 0.032 | uM | 7886.04 | 0.9499 | 0.8721 | 0.7771 | |
| MDA-MB-175-VII | HR+ | Luminal | 17-AAG | HSP90 | HSP90 | 0.16 | uM | 7886.04 | 0.3281 | -0.5233 | 0.7771 | |
| MDA-MB-175-VII | HR+ | Luminal | 17-AAG | HSP90 | HSP90 | 0.8 | uM | 7886.04 | 0.3099 | -0.5572 | 0.7771 | |
| MDA-MB-175-VII | HR+ | Luminal | 17-AAG | HSP90 | HSP90 | 4 | uM | 7886.04 | 0.2951 | -0.5841 | 0.7771 | |
| MDA-MB-175-VII | HR+ | Luminal | 17-AAG | HSP90 | HSP90 | 20 | uM | 7886.04 | 0.1764 | -0.7856 | 0.7771 | |
| MDA-MB-175-VII | HR+ | Luminal | 17-AAG | HSP90 | HSP90 | 100 | uM | 7886.04 | 0.3372 | -0.5064 | 0.7771 | |
| MDA-MB-175-VII | HR+ | Luminal | 17-AAG | HSP90 | HSP90 | 0.000256 | uM | 7886.05 | 1.0147 | 1.0472 | 0.6254 | |
| MDA-MB-175-VII | HR+ | Luminal | 17-AAG | HSP90 | HSP90 | 0.00128 | uM | 7886.05 | 1.0787 | 1.2576 | 0.6254 | |
| MDA-MB-175-VII | HR+ | Luminal | 17-AAG | HSP90 | HSP90 | 0.0064 | uM | 7886.05 | 1.0279 | 1.0900 | 0.6254 | |
| MDA-MB-175-VII | HR+ | Luminal | 17-AAG | HSP90 | HSP90 | 0.032 | uM | 7886.05 | 0.8233 | 0.4657 | 0.6254 | |
| MDA-MB-175-VII | HR+ | Luminal | 17-AAG | HSP90 | HSP90 | 0.16 | uM | 7886.05 | 0.3881 | -0.5597 | 0.6254 | |
| MDA-MB-175-VII | HR+ | Luminal | 17-AAG | HSP90 | HSP90 | 0.8 | uM | 7886.05 | 0.3925 | -0.5516 | 0.6254 | |
| MDA-MB-175-VII | HR+ | Luminal | 17-AAG | HSP90 | HSP90 | 4 | uM | 7886.05 | 0.3693 | -0.5933 | 0.6254 | |
| MDA-MB-175-VII | HR+ | Luminal | 17-AAG | HSP90 | HSP90 | 20 | uM | 7886.05 | 0.2712 | -0.7518 | 0.6254 |