Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset - HMS LINCS Database

Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)

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Small molecules	Cells	Antibodies

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Cell	Clinical Subtype	Transcriptional Subtype	Small Molecule	Perturbagen Target	Perturbagen Class	Perturbagen Concentration	Perturbagen Conc Unit	Biological Replicate ID	Relative Cell Count	Normalized Growth Rate Inhibition Value	Nominal Division Rate
MDA-MB-157	TNBC	Basal B	CPT-11	TOP1	TOP	2.95	uM	10093.034	0.6722	0.3298	0.9732
MDA-MB-157	TNBC	Basal B	CPT-11	TOP1	TOP	14.8	uM	10093.034	0.5965	0.1762	0.9732
MDA-MB-157	TNBC	Basal B	CPT-11	TOP1	TOP	73.8	uM	10093.034	0.0501	-0.9078	0.9732
MDA-MB-175-VII	HR+	Luminal	CPT-11	TOP1	TOP	0.000189	uM	7886.007	1.0292	1.0893	0.6601
MDA-MB-175-VII	HR+	Luminal	CPT-11	TOP1	TOP	0.000945	uM	7886.007	1.1071	1.3333	0.6601
MDA-MB-175-VII	HR+	Luminal	CPT-11	TOP1	TOP	0.00472	uM	7886.007	1.1239	1.3872	0.6601
MDA-MB-175-VII	HR+	Luminal	CPT-11	TOP1	TOP	0.0236	uM	7886.007	1.0794	1.2455	0.6601
MDA-MB-175-VII	HR+	Luminal	CPT-11	TOP1	TOP	0.118	uM	7886.007	1.0271	1.0825	0.6601
MDA-MB-175-VII	HR+	Luminal	CPT-11	TOP1	TOP	0.59	uM	7886.007	1.0722	1.2228	0.6601
MDA-MB-175-VII	HR+	Luminal	CPT-11	TOP1	TOP	2.95	uM	7886.007	0.9934	0.9801	0.6601
MDA-MB-175-VII	HR+	Luminal	CPT-11	TOP1	TOP	14.8	uM	7886.007	1.0414	1.1268	0.6601
MDA-MB-175-VII	HR+	Luminal	CPT-11	TOP1	TOP	73.8	uM	7886.007	0.7395	0.2662	0.6601
MDA-MB-175-VII	HR+	Luminal	CPT-11	TOP1	TOP	0.000189	uM	7886.043	0.9472	0.8489	0.6905
MDA-MB-175-VII	HR+	Luminal	CPT-11	TOP1	TOP	0.000945	uM	7886.043	0.9444	0.8411	0.6905
MDA-MB-175-VII	HR+	Luminal	CPT-11	TOP1	TOP	0.00472	uM	7886.043	1.0028	1.0080	0.6905
MDA-MB-175-VII	HR+	Luminal	CPT-11	TOP1	TOP	0.0236	uM	7886.043	0.9906	0.9728	0.6905
MDA-MB-175-VII	HR+	Luminal	CPT-11	TOP1	TOP	0.118	uM	7886.043	0.9526	0.8641	0.6905
MDA-MB-175-VII	HR+	Luminal	CPT-11	TOP1	TOP	0.59	uM	7886.043	0.9314	0.8043	0.6905
MDA-MB-175-VII	HR+	Luminal	CPT-11	TOP1	TOP	2.95	uM	7886.043	0.9609	0.8877	0.6905
MDA-MB-175-VII	HR+	Luminal	CPT-11	TOP1	TOP	14.8	uM	7886.043	1.0091	1.0265	0.6905
MDA-MB-175-VII	HR+	Luminal	CPT-11	TOP1	TOP	73.8	uM	7886.043	0.9025	0.7238	0.6905
MDA-MB-231	TNBC	Basal B	CPT-11	TOP1	TOP	0.000189	uM	7892.043	0.9267	0.9422	2.5944
MDA-MB-231	TNBC	Basal B	CPT-11	TOP1	TOP	0.000945	uM	7892.043	0.9002	0.9206	2.5944
MDA-MB-231	TNBC	Basal B	CPT-11	TOP1	TOP	0.00472	uM	7892.043	1.1254	1.0932	2.5944
MDA-MB-231	TNBC	Basal B	CPT-11	TOP1	TOP	0.0236	uM	7892.043	0.9792	0.9839	2.5944

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HMS LINCS Project

Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)