Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC70 | TNBC | Basal A | CGC-11047 | Polyamine analogue | 8 | uM | 7856.018 | 0.4875 | -0.0696 | 0.9388 | ||
| HCC70 | TNBC | Basal A | CGC-11047 | Polyamine analogue | 40 | uM | 7856.018 | 0.6243 | 0.2109 | 0.9388 | ||
| HCC70 | TNBC | Basal A | CGC-11047 | Polyamine analogue | 200 | uM | 7856.018 | 0.6094 | 0.1801 | 0.9388 | ||
| HCC70 | TNBC | Basal A | CGC-11047 | Polyamine analogue | 1000 | uM | 7856.018 | 0.1745 | -0.6885 | 0.9388 | ||
| HCC70 | TNBC | Basal A | CGC-11047 | Polyamine analogue | 5000 | uM | 7856.018 | 0.0130 | -0.9805 | 0.9388 | ||
| HCC70 | TNBC | Basal A | CGC-11047 | Polyamine analogue | 0.0128 | uM | 9501.026 | 0.9959 | 0.9893 | 0.7616 | ||
| HCC70 | TNBC | Basal A | CGC-11047 | Polyamine analogue | 0.064 | uM | 9501.026 | 0.9971 | 0.9923 | 0.7616 | ||
| HCC70 | TNBC | Basal A | CGC-11047 | Polyamine analogue | 0.32 | uM | 9501.026 | 0.9252 | 0.8059 | 0.7616 | ||
| HCC70 | TNBC | Basal A | CGC-11047 | Polyamine analogue | 1.6 | uM | 9501.026 | 0.5139 | -0.1656 | 0.7616 | ||
| HCC70 | TNBC | Basal A | CGC-11047 | Polyamine analogue | 8 | uM | 9501.026 | 0.5602 | -0.0655 | 0.7616 | ||
| HCC70 | TNBC | Basal A | CGC-11047 | Polyamine analogue | 40 | uM | 9501.026 | 0.5532 | -0.0808 | 0.7616 | ||
| HCC70 | TNBC | Basal A | CGC-11047 | Polyamine analogue | 200 | uM | 9501.026 | 0.5403 | -0.1089 | 0.7616 | ||
| HCC70 | TNBC | Basal A | CGC-11047 | Polyamine analogue | 1000 | uM | 9501.026 | 0.0519 | -0.9589 | 0.7616 | ||
| HCC70 | TNBC | Basal A | CGC-11047 | Polyamine analogue | 5000 | uM | 9501.026 | 0.0330 | -0.9773 | 0.7616 | ||
| HMT-3522 S1 | Unknown | Unknown | CGC-11047 | Polyamine analogue | 0.0128 | uM | 7911.018 | 1.0350 | 1.0375 | 1.8543 | ||
| HMT-3522 S1 | Unknown | Unknown | CGC-11047 | Polyamine analogue | 0.064 | uM | 7911.018 | 0.9589 | 0.9552 | 1.8543 | ||
| HMT-3522 S1 | Unknown | Unknown | CGC-11047 | Polyamine analogue | 0.32 | uM | 7911.018 | 0.8952 | 0.8841 | 1.8543 | ||
| HMT-3522 S1 | Unknown | Unknown | CGC-11047 | Polyamine analogue | 1.6 | uM | 7911.018 | 0.5289 | 0.4185 | 1.8543 | ||
| HMT-3522 S1 | Unknown | Unknown | CGC-11047 | Polyamine analogue | 8 | uM | 7911.018 | 0.5939 | 0.5100 | 1.8543 | ||
| HMT-3522 S1 | Unknown | Unknown | CGC-11047 | Polyamine analogue | 40 | uM | 7911.018 | 0.5666 | 0.4722 | 1.8543 | ||
| HMT-3522 S1 | Unknown | Unknown | CGC-11047 | Polyamine analogue | 200 | uM | 7911.018 | 0.6268 | 0.5547 | 1.8543 | ||
| HMT-3522 S1 | Unknown | Unknown | CGC-11047 | Polyamine analogue | 1000 | uM | 7911.018 | 0.4184 | 0.2502 | 1.8543 | ||
| HMT-3522 S1 | Unknown | Unknown | CGC-11047 | Polyamine analogue | 5000 | uM | 7911.018 | 0.0170 | -0.7780 | 1.8543 | ||
| HMT-3522 S1 | Unknown | Unknown | CGC-11047 | Polyamine analogue | 0.0128 | uM | 10124.034 | 0.9986 | 0.9988 | 2.2594 | ||
| HMT-3522 S1 | Unknown | Unknown | CGC-11047 | Polyamine analogue | 0.064 | uM | 10124.034 | 0.9801 | 0.9823 | 2.2594 |