Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC38 | TNBC | Basal B | CGC-11047 | Polyamine analogue | 200 | uM | 9453.125 | 0.5094 | 0.1584 | 1.2351 | ||
| HCC38 | TNBC | Basal B | CGC-11047 | Polyamine analogue | 1000 | uM | 9453.125 | 0.1009 | -0.6877 | 1.2351 | ||
| HCC38 | TNBC | Basal B | CGC-11047 | Polyamine analogue | 5000 | uM | 9453.125 | 0.0071 | -0.9634 | 1.2351 | ||
| HCC38 | TNBC | Basal B | CGC-11047 | Polyamine analogue | 0.0128 | uM | 9469.026 | 0.9928 | 0.9881 | 1.2092 | ||
| HCC38 | TNBC | Basal B | CGC-11047 | Polyamine analogue | 0.064 | uM | 9469.026 | 0.9689 | 0.9484 | 1.2092 | ||
| HCC38 | TNBC | Basal B | CGC-11047 | Polyamine analogue | 0.32 | uM | 9469.026 | 0.9213 | 0.8688 | 1.2092 | ||
| HCC38 | TNBC | Basal B | CGC-11047 | Polyamine analogue | 1.6 | uM | 9469.026 | 0.8370 | 0.7263 | 1.2092 | ||
| HCC38 | TNBC | Basal B | CGC-11047 | Polyamine analogue | 8 | uM | 9469.026 | 0.8118 | 0.6833 | 1.2092 | ||
| HCC38 | TNBC | Basal B | CGC-11047 | Polyamine analogue | 40 | uM | 9469.026 | 0.8102 | 0.6805 | 1.2092 | ||
| HCC38 | TNBC | Basal B | CGC-11047 | Polyamine analogue | 200 | uM | 9469.026 | 0.7313 | 0.5440 | 1.2092 | ||
| HCC38 | TNBC | Basal B | CGC-11047 | Polyamine analogue | 1000 | uM | 9469.026 | 0.0664 | -0.7878 | 1.2092 | ||
| HCC38 | TNBC | Basal B | CGC-11047 | Polyamine analogue | 5000 | uM | 9469.026 | 0.0069 | -0.9676 | 1.2092 | ||
| HCC38 | TNBC | Basal B | CGC-11047 | Polyamine analogue | 0.0000853 | uM | 10268.122 | 1.0091 | 1.0288 | 0.6345 | ||
| HCC38 | TNBC | Basal B | CGC-11047 | Polyamine analogue | 0.000427 | uM | 10268.122 | 0.9835 | 0.9483 | 0.6345 | ||
| HCC38 | TNBC | Basal B | CGC-11047 | Polyamine analogue | 0.00213 | uM | 10268.122 | 1.1618 | 1.5334 | 0.6345 | ||
| HCC38 | TNBC | Basal B | CGC-11047 | Polyamine analogue | 0.0107 | uM | 10268.122 | 0.9902 | 0.9692 | 0.6345 | ||
| HCC38 | TNBC | Basal B | CGC-11047 | Polyamine analogue | 0.0533 | uM | 10268.122 | 1.1053 | 1.3418 | 0.6345 | ||
| HCC38 | TNBC | Basal B | CGC-11047 | Polyamine analogue | 0.267 | uM | 10268.122 | 1.1821 | 1.6033 | 0.6345 | ||
| HCC38 | TNBC | Basal B | CGC-11047 | Polyamine analogue | 1.33 | uM | 10268.122 | 1.0343 | 1.1091 | 0.6345 | ||
| HCC38 | TNBC | Basal B | CGC-11047 | Polyamine analogue | 6.67 | uM | 10268.122 | 0.7077 | 0.1599 | 0.6345 | ||
| HCC38 | TNBC | Basal B | CGC-11047 | Polyamine analogue | 33.3 | uM | 10268.122 | 0.5456 | -0.2302 | 0.6345 | ||
| HCC70 | TNBC | Basal A | CGC-11047 | Polyamine analogue | 0.0128 | uM | 7856.018 | 1.0877 | 1.1874 | 0.9388 | ||
| HCC70 | TNBC | Basal A | CGC-11047 | Polyamine analogue | 0.064 | uM | 7856.018 | 0.9825 | 0.9627 | 0.9388 | ||
| HCC70 | TNBC | Basal A | CGC-11047 | Polyamine analogue | 0.32 | uM | 7856.018 | 1.0269 | 1.0573 | 0.9388 | ||
| HCC70 | TNBC | Basal A | CGC-11047 | Polyamine analogue | 1.6 | uM | 7856.018 | 0.7011 | 0.3702 | 0.9388 |