Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MDA-MB-453 | TNBC | Luminal | Bortezomib | Proteasome | Proteasome | 1.33 | uM | 7518.074 | 0.1464 | -0.3891 | 1.6204 | |
| MDA-MB-453 | TNBC | Luminal | Bortezomib | Proteasome | Proteasome | 1.33 | uM | 7518.074 | 0.1464 | -0.3891 | 1.6204 | |
| MDA-MB-453 | TNBC | Luminal | Bortezomib | Proteasome | Proteasome | 6.67 | uM | 7518.074 | 0.1047 | -0.5032 | 1.6204 | |
| MDA-MB-453 | TNBC | Luminal | Bortezomib | Proteasome | Proteasome | 6.67 | uM | 7518.074 | 0.1047 | -0.5032 | 1.6204 | |
| MDA-MB-453 | TNBC | Luminal | Bortezomib | Proteasome | Proteasome | 33.3 | uM | 7518.074 | 0.0814 | -0.5747 | 1.6204 | |
| MDA-MB-453 | TNBC | Luminal | Bortezomib | Proteasome | Proteasome | 33.3 | uM | 7518.074 | 0.0814 | -0.5747 | 1.6204 | |
| MDA-MB-453 | TNBC | Luminal | Bortezomib | Proteasome | Proteasome | 167 | uM | 7518.074 | 0.0701 | -0.6120 | 1.6204 | |
| MDA-MB-453 | TNBC | Luminal | Bortezomib | Proteasome | Proteasome | 167 | uM | 7518.074 | 0.0701 | -0.6120 | 1.6204 | |
| MDA-MB-453 | TNBC | Luminal | Bortezomib | Proteasome | Proteasome | 0.000171 | uM | 14771.203 | 0.9637 | 0.9360 | 1.1364 | |
| MDA-MB-453 | TNBC | Luminal | Bortezomib | Proteasome | Proteasome | 0.000171 | uM | 14771.203 | 0.9637 | 0.9360 | 1.1364 | |
| MDA-MB-453 | TNBC | Luminal | Bortezomib | Proteasome | Proteasome | 0.000853 | uM | 14771.203 | 0.8980 | 0.8193 | 1.1364 | |
| MDA-MB-453 | TNBC | Luminal | Bortezomib | Proteasome | Proteasome | 0.000853 | uM | 14771.203 | 0.8980 | 0.8193 | 1.1364 | |
| MDA-MB-453 | TNBC | Luminal | Bortezomib | Proteasome | Proteasome | 0.00427 | uM | 14771.203 | 0.9263 | 0.8697 | 1.1364 | |
| MDA-MB-453 | TNBC | Luminal | Bortezomib | Proteasome | Proteasome | 0.00427 | uM | 14771.203 | 0.9263 | 0.8697 | 1.1364 | |
| MDA-MB-453 | TNBC | Luminal | Bortezomib | Proteasome | Proteasome | 0.0213 | uM | 14771.203 | 0.5565 | 0.1940 | 1.1364 | |
| MDA-MB-453 | TNBC | Luminal | Bortezomib | Proteasome | Proteasome | 0.0213 | uM | 14771.203 | 0.5565 | 0.1940 | 1.1364 | |
| MDA-MB-453 | TNBC | Luminal | Bortezomib | Proteasome | Proteasome | 0.107 | uM | 14771.203 | 0.3812 | -0.1441 | 1.1364 | |
| MDA-MB-453 | TNBC | Luminal | Bortezomib | Proteasome | Proteasome | 0.107 | uM | 14771.203 | 0.3812 | -0.1441 | 1.1364 | |
| MDA-MB-453 | TNBC | Luminal | Bortezomib | Proteasome | Proteasome | 0.533 | uM | 14771.203 | 0.3100 | -0.2865 | 1.1364 | |
| MDA-MB-453 | TNBC | Luminal | Bortezomib | Proteasome | Proteasome | 0.533 | uM | 14771.203 | 0.3100 | -0.2865 | 1.1364 | |
| MDA-MB-453 | TNBC | Luminal | Bortezomib | Proteasome | Proteasome | 2.67 | uM | 14771.203 | 0.2550 | -0.3992 | 1.1364 | |
| MDA-MB-453 | TNBC | Luminal | Bortezomib | Proteasome | Proteasome | 2.67 | uM | 14771.203 | 0.2550 | -0.3992 | 1.1364 | |
| MDA-MB-453 | TNBC | Luminal | Bortezomib | Proteasome | Proteasome | 13.3 | uM | 14771.203 | 0.1877 | -0.5411 | 1.1364 | |
| MDA-MB-453 | TNBC | Luminal | Bortezomib | Proteasome | Proteasome | 13.3 | uM | 14771.203 | 0.1877 | -0.5411 | 1.1364 | |
| MDA-MB-453 | TNBC | Luminal | Bortezomib | Proteasome | Proteasome | 66.7 | uM | 14771.203 | 0.1645 | -0.5915 | 1.1364 |