Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AU565 | HER2amp | Luminal | Vorinostat | HDAC | HDAC | 1.2 | uM | 5900.065 | 0.9841 | 0.9855 | 2.2026 | |
| AU565 | HER2amp | Luminal | Vorinostat | HDAC | HDAC | 6 | uM | 5900.065 | 1.0184 | 1.0166 | 2.2026 | |
| AU565 | HER2amp | Luminal | Vorinostat | HDAC | HDAC | 30 | uM | 5900.065 | 0.9106 | 0.9168 | 2.2026 | |
| AU565 | HER2amp | Luminal | Vorinostat | HDAC | HDAC | 150 | uM | 5900.065 | 0.2635 | 0.0916 | 2.2026 | |
| AU565 | HER2amp | Luminal | Vorinostat | HDAC | HDAC | 750 | uM | 5900.065 | 0.0048 | -0.8233 | 2.2026 | |
| AU565 | HER2amp | Luminal | Vorinostat | HDAC | HDAC | 3750 | uM | 5900.065 | 0.0054 | -0.8124 | 2.2026 | |
| AU565 | HER2amp | Luminal | Vorinostat | HDAC | HDAC | 18700 | uM | 5900.065 | 0.0046 | -0.8266 | 2.2026 | |
| AU565 | HER2amp | Luminal | Vorinostat | HDAC | HDAC | 0.048 | uM | 5901.065 | 0.9566 | 0.9563 | 2.0114 | |
| AU565 | HER2amp | Luminal | Vorinostat | HDAC | HDAC | 0.24 | uM | 5901.065 | 0.9693 | 0.9693 | 2.0114 | |
| AU565 | HER2amp | Luminal | Vorinostat | HDAC | HDAC | 1.2 | uM | 5901.065 | 0.9606 | 0.9604 | 2.0114 | |
| AU565 | HER2amp | Luminal | Vorinostat | HDAC | HDAC | 6 | uM | 5901.065 | 0.9650 | 0.9649 | 2.0114 | |
| AU565 | HER2amp | Luminal | Vorinostat | HDAC | HDAC | 30 | uM | 5901.065 | 0.9114 | 0.9099 | 2.0114 | |
| AU565 | HER2amp | Luminal | Vorinostat | HDAC | HDAC | 150 | uM | 5901.065 | 0.2588 | 0.0213 | 2.0114 | |
| AU565 | HER2amp | Luminal | Vorinostat | HDAC | HDAC | 750 | uM | 5901.065 | 0.0066 | -0.8356 | 2.0114 | |
| AU565 | HER2amp | Luminal | Vorinostat | HDAC | HDAC | 3750 | uM | 5901.065 | 0.0081 | -0.8175 | 2.0114 | |
| AU565 | HER2amp | Luminal | Vorinostat | HDAC | HDAC | 18700 | uM | 5901.065 | 0.0050 | -0.8560 | 2.0114 | |
| BT-20 | TNBC | Basal A | Vorinostat | HDAC | HDAC | 0.048 | uM | 5902.065 | 0.8920 | 0.8278 | 1.2690 | |
| BT-20 | TNBC | Basal A | Vorinostat | HDAC | HDAC | 0.24 | uM | 5902.065 | 0.9799 | 0.9683 | 1.2690 | |
| BT-20 | TNBC | Basal A | Vorinostat | HDAC | HDAC | 1.2 | uM | 5902.065 | 0.9613 | 0.9388 | 1.2690 | |
| BT-20 | TNBC | Basal A | Vorinostat | HDAC | HDAC | 6 | uM | 5902.065 | 0.9543 | 0.9276 | 1.2690 | |
| BT-20 | TNBC | Basal A | Vorinostat | HDAC | HDAC | 30 | uM | 5902.065 | 0.9158 | 0.8660 | 1.2690 | |
| BT-20 | TNBC | Basal A | Vorinostat | HDAC | HDAC | 150 | uM | 5902.065 | 0.8076 | 0.6901 | 1.2690 | |
| BT-20 | TNBC | Basal A | Vorinostat | HDAC | HDAC | 750 | uM | 5902.065 | 0.4112 | -0.0072 | 1.2690 | |
| BT-20 | TNBC | Basal A | Vorinostat | HDAC | HDAC | 3750 | uM | 5902.065 | 0.1210 | -0.6213 | 1.2690 | |
| BT-20 | TNBC | Basal A | Vorinostat | HDAC | HDAC | 18700 | uM | 5902.065 | 0.0839 | -0.7163 | 1.2690 |