Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
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184A1 | NM | Basal | Vorinostat | HDAC | HDAC | 750 | uM | 5894.065 | 0.4355 | 0.1921 | 1.6064 | |
184A1 | NM | Basal | Vorinostat | HDAC | HDAC | 3750 | uM | 5894.065 | 0.2040 | -0.2565 | 1.6064 | |
184A1 | NM | Basal | Vorinostat | HDAC | HDAC | 18700 | uM | 5894.065 | 0.1467 | -0.3946 | 1.6064 | |
184A1 | NM | Basal | Vorinostat | HDAC | HDAC | 0.048 | uM | 5895.065 | 1.0436 | 1.0631 | 1.3748 | |
184A1 | NM | Basal | Vorinostat | HDAC | HDAC | 0.24 | uM | 5895.065 | 1.0436 | 1.0630 | 1.3748 | |
184A1 | NM | Basal | Vorinostat | HDAC | HDAC | 1.2 | uM | 5895.065 | 0.9828 | 0.9749 | 1.3748 | |
184A1 | NM | Basal | Vorinostat | HDAC | HDAC | 6 | uM | 5895.065 | 1.0025 | 1.0037 | 1.3748 | |
184A1 | NM | Basal | Vorinostat | HDAC | HDAC | 30 | uM | 5895.065 | 0.8523 | 0.7805 | 1.3748 | |
184A1 | NM | Basal | Vorinostat | HDAC | HDAC | 150 | uM | 5895.065 | 0.6009 | 0.3809 | 1.3748 | |
184A1 | NM | Basal | Vorinostat | HDAC | HDAC | 750 | uM | 5895.065 | 0.4462 | 0.1121 | 1.3748 | |
184A1 | NM | Basal | Vorinostat | HDAC | HDAC | 3750 | uM | 5895.065 | 0.2063 | -0.3655 | 1.3748 | |
184A1 | NM | Basal | Vorinostat | HDAC | HDAC | 18700 | uM | 5895.065 | 0.0840 | -0.6699 | 1.3748 | |
184B5 | NM | Basal | Vorinostat | HDAC | HDAC | 0.048 | uM | 5896.065 | 0.9564 | 0.9414 | 1.4978 | |
184B5 | NM | Basal | Vorinostat | HDAC | HDAC | 0.24 | uM | 5896.065 | 0.9741 | 0.9652 | 1.4978 | |
184B5 | NM | Basal | Vorinostat | HDAC | HDAC | 1.2 | uM | 5896.065 | 0.9773 | 0.9695 | 1.4978 | |
184B5 | NM | Basal | Vorinostat | HDAC | HDAC | 6 | uM | 5896.065 | 0.9352 | 0.9125 | 1.4978 | |
184B5 | NM | Basal | Vorinostat | HDAC | HDAC | 30 | uM | 5896.065 | 0.7679 | 0.6768 | 1.4978 | |
184B5 | NM | Basal | Vorinostat | HDAC | HDAC | 150 | uM | 5896.065 | 0.5516 | 0.3443 | 1.4978 | |
184B5 | NM | Basal | Vorinostat | HDAC | HDAC | 750 | uM | 5896.065 | 0.4378 | 0.1523 | 1.4978 | |
184B5 | NM | Basal | Vorinostat | HDAC | HDAC | 3750 | uM | 5896.065 | 0.2048 | -0.3062 | 1.4978 | |
184B5 | NM | Basal | Vorinostat | HDAC | HDAC | 18700 | uM | 5896.065 | 0.0296 | -0.8093 | 1.4978 | |
184B5 | NM | Basal | Vorinostat | HDAC | HDAC | 0.048 | uM | 5897.065 | 0.9291 | 0.8899 | 1.2996 | |
184B5 | NM | Basal | Vorinostat | HDAC | HDAC | 0.24 | uM | 5897.065 | 0.9995 | 0.9993 | 1.2996 | |
184B5 | NM | Basal | Vorinostat | HDAC | HDAC | 1.2 | uM | 5897.065 | 0.9286 | 0.8891 | 1.2996 | |
184B5 | NM | Basal | Vorinostat | HDAC | HDAC | 6 | uM | 5897.065 | 0.9485 | 0.9202 | 1.2996 |