Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
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184A1 | NM | Basal | Triciribine | AKT | AKT | 1.33 | uM | 5895.074 | 0.2713 | -0.3750 | 1.1218 | |
184A1 | NM | Basal | Triciribine | AKT | AKT | 6.67 | uM | 5895.074 | 0.1873 | -0.5506 | 1.1218 | |
184A1 | NM | Basal | Triciribine | AKT | AKT | 33.3 | uM | 5895.074 | 0.0890 | -0.7686 | 1.1218 | |
184B5 | NM | Basal | Triciribine | AKT | AKT | 0.0000853 | uM | 5896.074 | 1.0117 | 1.0166 | 1.4124 | |
184B5 | NM | Basal | Triciribine | AKT | AKT | 0.000427 | uM | 5896.074 | 0.9980 | 0.9972 | 1.4124 | |
184B5 | NM | Basal | Triciribine | AKT | AKT | 0.00213 | uM | 5896.074 | 0.9570 | 0.9388 | 1.4124 | |
184B5 | NM | Basal | Triciribine | AKT | AKT | 0.0107 | uM | 5896.074 | 0.8969 | 0.8516 | 1.4124 | |
184B5 | NM | Basal | Triciribine | AKT | AKT | 0.0533 | uM | 5896.074 | 0.7436 | 0.6215 | 1.4124 | |
184B5 | NM | Basal | Triciribine | AKT | AKT | 0.267 | uM | 5896.074 | 0.4524 | 0.1406 | 1.4124 | |
184B5 | NM | Basal | Triciribine | AKT | AKT | 1.33 | uM | 5896.074 | 0.3030 | -0.1413 | 1.4124 | |
184B5 | NM | Basal | Triciribine | AKT | AKT | 6.67 | uM | 5896.074 | 0.1570 | -0.4609 | 1.4124 | |
184B5 | NM | Basal | Triciribine | AKT | AKT | 33.3 | uM | 5896.074 | 0.0802 | -0.6648 | 1.4124 | |
184B5 | NM | Basal | Triciribine | AKT | AKT | 0.0000853 | uM | 5897.074 | 0.9474 | 0.9174 | 1.2824 | |
184B5 | NM | Basal | Triciribine | AKT | AKT | 0.000427 | uM | 5897.074 | 0.9657 | 0.9463 | 1.2824 | |
184B5 | NM | Basal | Triciribine | AKT | AKT | 0.00213 | uM | 5897.074 | 0.9464 | 0.9159 | 1.2824 | |
184B5 | NM | Basal | Triciribine | AKT | AKT | 0.0107 | uM | 5897.074 | 0.9452 | 0.9141 | 1.2824 | |
184B5 | NM | Basal | Triciribine | AKT | AKT | 0.0533 | uM | 5897.074 | 0.9269 | 0.8850 | 1.2824 | |
184B5 | NM | Basal | Triciribine | AKT | AKT | 0.267 | uM | 5897.074 | 0.4995 | 0.1640 | 1.2824 | |
184B5 | NM | Basal | Triciribine | AKT | AKT | 1.33 | uM | 5897.074 | 0.1987 | -0.4328 | 1.2824 | |
184B5 | NM | Basal | Triciribine | AKT | AKT | 6.67 | uM | 5897.074 | 0.1492 | -0.5464 | 1.2824 | |
184B5 | NM | Basal | Triciribine | AKT | AKT | 33.3 | uM | 5897.074 | 0.0950 | -0.6810 | 1.2824 | |
600MPE | HR+ | Luminal | Triciribine | AKT | AKT | 0.0000853 | uM | 5898.074 | 0.9764 | 0.9342 | 0.7134 | |
600MPE | HR+ | Luminal | Triciribine | AKT | AKT | 0.000427 | uM | 5898.074 | 0.9265 | 0.7971 | 0.7134 | |
600MPE | HR+ | Luminal | Triciribine | AKT | AKT | 0.00213 | uM | 5898.074 | 0.9737 | 0.9265 | 0.7134 | |
600MPE | HR+ | Luminal | Triciribine | AKT | AKT | 0.0107 | uM | 5898.074 | 0.9723 | 0.9227 | 0.7134 |