Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)

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Cell Clinical Subtype Transcriptional Subtype Small Molecule Antibody Perturbagen Target Perturbagen Class Perturbagen Concentration Perturbagen Conc Unit Biological Replicate ID Relative Cell Count Normalized Growth Rate Inhibition Value Nominal Division Rate
184A1
NM
Basal
Triciribine
AKT
AKT
1.33
uM
5895.074
0.2713 -0.3750 1.1218
184A1
NM
Basal
Triciribine
AKT
AKT
6.67
uM
5895.074
0.1873 -0.5506 1.1218
184A1
NM
Basal
Triciribine
AKT
AKT
33.3
uM
5895.074
0.0890 -0.7686 1.1218
184B5
NM
Basal
Triciribine
AKT
AKT
0.0000853
uM
5896.074
1.0117 1.0166 1.4124
184B5
NM
Basal
Triciribine
AKT
AKT
0.000427
uM
5896.074
0.9980 0.9972 1.4124
184B5
NM
Basal
Triciribine
AKT
AKT
0.00213
uM
5896.074
0.9570 0.9388 1.4124
184B5
NM
Basal
Triciribine
AKT
AKT
0.0107
uM
5896.074
0.8969 0.8516 1.4124
184B5
NM
Basal
Triciribine
AKT
AKT
0.0533
uM
5896.074
0.7436 0.6215 1.4124
184B5
NM
Basal
Triciribine
AKT
AKT
0.267
uM
5896.074
0.4524 0.1406 1.4124
184B5
NM
Basal
Triciribine
AKT
AKT
1.33
uM
5896.074
0.3030 -0.1413 1.4124
184B5
NM
Basal
Triciribine
AKT
AKT
6.67
uM
5896.074
0.1570 -0.4609 1.4124
184B5
NM
Basal
Triciribine
AKT
AKT
33.3
uM
5896.074
0.0802 -0.6648 1.4124
184B5
NM
Basal
Triciribine
AKT
AKT
0.0000853
uM
5897.074
0.9474 0.9174 1.2824
184B5
NM
Basal
Triciribine
AKT
AKT
0.000427
uM
5897.074
0.9657 0.9463 1.2824
184B5
NM
Basal
Triciribine
AKT
AKT
0.00213
uM
5897.074
0.9464 0.9159 1.2824
184B5
NM
Basal
Triciribine
AKT
AKT
0.0107
uM
5897.074
0.9452 0.9141 1.2824
184B5
NM
Basal
Triciribine
AKT
AKT
0.0533
uM
5897.074
0.9269 0.8850 1.2824
184B5
NM
Basal
Triciribine
AKT
AKT
0.267
uM
5897.074
0.4995 0.1640 1.2824
184B5
NM
Basal
Triciribine
AKT
AKT
1.33
uM
5897.074
0.1987 -0.4328 1.2824
184B5
NM
Basal
Triciribine
AKT
AKT
6.67
uM
5897.074
0.1492 -0.5464 1.2824
184B5
NM
Basal
Triciribine
AKT
AKT
33.3
uM
5897.074
0.0950 -0.6810 1.2824
600MPE
HR+
Luminal
Triciribine
AKT
AKT
0.0000853
uM
5898.074
0.9764 0.9342 0.7134
600MPE
HR+
Luminal
Triciribine
AKT
AKT
0.000427
uM
5898.074
0.9265 0.7971 0.7134
600MPE
HR+
Luminal
Triciribine
AKT
AKT
0.00213
uM
5898.074
0.9737 0.9265 0.7134
600MPE
HR+
Luminal
Triciribine
AKT
AKT
0.0107
uM
5898.074
0.9723 0.9227 0.7134