Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SUM149PT | TNBC | Basal B | AS-252424 | PI3K | PI3K | 0.533 | uM | 11937.158 | 1.0261 | 1.0232 | 2.2386 | |
| SUM149PT | TNBC | Basal B | AS-252424 | PI3K | PI3K | 2.67 | uM | 11937.158 | 0.9131 | 0.9204 | 2.2386 | |
| SUM149PT | TNBC | Basal B | AS-252424 | PI3K | PI3K | 13.3 | uM | 11937.158 | 0.5235 | 0.4978 | 2.2386 | |
| SUM149PT | TNBC | Basal B | AS-252424 | PI3K | PI3K | 66.7 | uM | 11937.158 | 0.4161 | 0.3519 | 2.2386 | |
| SUM159PT | TNBC | Basal B | AS-252424 | PI3K | PI3K | 0.000171 | uM | 10520.141 | 1.2749 | 1.1381 | 3.6374 | |
| SUM159PT | TNBC | Basal B | AS-252424 | PI3K | PI3K | 0.000853 | uM | 10520.141 | 0.9889 | 0.9939 | 3.6374 | |
| SUM159PT | TNBC | Basal B | AS-252424 | PI3K | PI3K | 0.00427 | uM | 10520.141 | 0.8882 | 0.9359 | 3.6374 | |
| SUM159PT | TNBC | Basal B | AS-252424 | PI3K | PI3K | 0.0213 | uM | 10520.141 | 1.1019 | 1.0541 | 3.6374 | |
| SUM159PT | TNBC | Basal B | AS-252424 | PI3K | PI3K | 0.107 | uM | 10520.141 | 1.0233 | 1.0127 | 3.6374 | |
| SUM159PT | TNBC | Basal B | AS-252424 | PI3K | PI3K | 0.533 | uM | 10520.141 | 0.7796 | 0.8677 | 3.6374 | |
| SUM159PT | TNBC | Basal B | AS-252424 | PI3K | PI3K | 2.67 | uM | 10520.141 | 0.8600 | 0.9187 | 3.6374 | |
| SUM159PT | TNBC | Basal B | AS-252424 | PI3K | PI3K | 13.3 | uM | 10520.141 | 0.3129 | 0.4531 | 3.6374 | |
| SUM159PT | TNBC | Basal B | AS-252424 | PI3K | PI3K | 66.7 | uM | 10520.141 | 0.2555 | 0.3744 | 3.6374 | |
| SUM159PT | TNBC | Basal B | AS-252424 | PI3K | PI3K | 0.000171 | uM | 11057.158 | 0.9759 | 0.9874 | 3.8594 | |
| SUM159PT | TNBC | Basal B | AS-252424 | PI3K | PI3K | 0.000853 | uM | 11057.158 | 1.0081 | 1.0042 | 3.8594 | |
| SUM159PT | TNBC | Basal B | AS-252424 | PI3K | PI3K | 0.00427 | uM | 11057.158 | 1.1924 | 1.0933 | 3.8594 | |
| SUM159PT | TNBC | Basal B | AS-252424 | PI3K | PI3K | 0.0213 | uM | 11057.158 | 1.0981 | 1.0491 | 3.8594 | |
| SUM159PT | TNBC | Basal B | AS-252424 | PI3K | PI3K | 0.107 | uM | 11057.158 | 1.0123 | 1.0063 | 3.8594 | |
| SUM159PT | TNBC | Basal B | AS-252424 | PI3K | PI3K | 0.533 | uM | 11057.158 | 0.9593 | 0.9786 | 3.8594 | |
| SUM159PT | TNBC | Basal B | AS-252424 | PI3K | PI3K | 2.67 | uM | 11057.158 | 0.7556 | 0.8599 | 3.8594 | |
| SUM159PT | TNBC | Basal B | AS-252424 | PI3K | PI3K | 13.3 | uM | 11057.158 | 0.3076 | 0.4735 | 3.8594 | |
| SUM159PT | TNBC | Basal B | AS-252424 | PI3K | PI3K | 66.7 | uM | 11057.158 | 0.5152 | 0.6842 | 3.8594 | |
| SUM185PE | TNBC | Luminal | AS-252424 | PI3K | PI3K | 0.0000853 | uM | 12269.165 | 1.4328 | 2.6416 | 0.6001 | |
| SUM185PE | TNBC | Luminal | AS-252424 | PI3K | PI3K | 0.000427 | uM | 12269.165 | 1.3792 | 2.4177 | 0.6001 | |
| SUM185PE | TNBC | Luminal | AS-252424 | PI3K | PI3K | 0.00213 | uM | 12269.165 | 1.0665 | 1.2265 | 0.6001 |