Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
Download: Excel (XLSX), Comma-separated (CSV)
| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SUM149PT | TNBC | Basal B | Temsirolimus | MTOR | MTOR | 5.33 | uM | 10819.144 | 0.7042 | 0.7095 | 2.2343 | |
| SUM149PT | TNBC | Basal B | Temsirolimus | MTOR | MTOR | 26.7 | uM | 10819.144 | 0.2597 | 0.0938 | 2.2343 | |
| SUM149PT | TNBC | Basal B | Temsirolimus | MTOR | MTOR | 133 | uM | 10819.144 | 0.0011 | -0.9054 | 2.2343 | |
| SUM149PT | TNBC | Basal B | Temsirolimus | MTOR | MTOR | 0.000341 | uM | 11937.144 | 0.9315 | 0.9424 | 2.4293 | |
| SUM149PT | TNBC | Basal B | Temsirolimus | MTOR | MTOR | 0.00171 | uM | 11937.144 | 0.9259 | 0.9376 | 2.4293 | |
| SUM149PT | TNBC | Basal B | Temsirolimus | MTOR | MTOR | 0.00853 | uM | 11937.144 | 0.9795 | 0.9831 | 2.4293 | |
| SUM149PT | TNBC | Basal B | Temsirolimus | MTOR | MTOR | 0.0427 | uM | 11937.144 | 0.8272 | 0.8498 | 2.4293 | |
| SUM149PT | TNBC | Basal B | Temsirolimus | MTOR | MTOR | 0.213 | uM | 11937.144 | 0.6934 | 0.7202 | 2.4293 | |
| SUM149PT | TNBC | Basal B | Temsirolimus | MTOR | MTOR | 1.07 | uM | 11937.144 | 0.6705 | 0.6965 | 2.4293 | |
| SUM149PT | TNBC | Basal B | Temsirolimus | MTOR | MTOR | 5.33 | uM | 11937.144 | 0.7095 | 0.7365 | 2.4293 | |
| SUM149PT | TNBC | Basal B | Temsirolimus | MTOR | MTOR | 26.7 | uM | 11937.144 | 0.0294 | -0.5319 | 2.4293 | |
| SUM149PT | TNBC | Basal B | Temsirolimus | MTOR | MTOR | 133 | uM | 11937.144 | 0.0048 | -0.7784 | 2.4293 | |
| SUM159PT | TNBC | Basal B | Temsirolimus | MTOR | MTOR | 0.000341 | uM | 11057.144 | 1.0457 | 1.0238 | 3.7784 | |
| SUM159PT | TNBC | Basal B | Temsirolimus | MTOR | MTOR | 0.00171 | uM | 11057.144 | 0.9310 | 0.9625 | 3.7784 | |
| SUM159PT | TNBC | Basal B | Temsirolimus | MTOR | MTOR | 0.00853 | uM | 11057.144 | 0.7510 | 0.8540 | 3.7784 | |
| SUM159PT | TNBC | Basal B | Temsirolimus | MTOR | MTOR | 0.0427 | uM | 11057.144 | 0.5511 | 0.7082 | 3.7784 | |
| SUM159PT | TNBC | Basal B | Temsirolimus | MTOR | MTOR | 0.213 | uM | 11057.144 | 0.4444 | 0.6137 | 3.7784 | |
| SUM159PT | TNBC | Basal B | Temsirolimus | MTOR | MTOR | 1.07 | uM | 11057.144 | 0.4320 | 0.6016 | 3.7784 | |
| SUM159PT | TNBC | Basal B | Temsirolimus | MTOR | MTOR | 5.33 | uM | 11057.144 | 0.4287 | 0.5983 | 3.7784 | |
| SUM159PT | TNBC | Basal B | Temsirolimus | MTOR | MTOR | 26.7 | uM | 11057.144 | 0.1786 | 0.2677 | 3.7784 | |
| SUM159PT | TNBC | Basal B | Temsirolimus | MTOR | MTOR | 133 | uM | 11057.144 | 0.0004 | -0.7417 | 3.7784 | |
| SUM185PE | TNBC | Luminal | Temsirolimus | MTOR | MTOR | 0.000341 | uM | 12269.144 | 0.9214 | 0.8463 | 1.0241 | |
| SUM185PE | TNBC | Luminal | Temsirolimus | MTOR | MTOR | 0.00171 | uM | 12269.144 | 0.6489 | 0.3111 | 1.0241 | |
| SUM185PE | TNBC | Luminal | Temsirolimus | MTOR | MTOR | 0.00853 | uM | 12269.144 | 0.3715 | -0.2395 | 1.0241 | |
| SUM185PE | TNBC | Luminal | Temsirolimus | MTOR | MTOR | 0.0427 | uM | 12269.144 | 0.7554 | 0.5208 | 1.0241 |