Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MX1 | Unknown | Unknown | Temsirolimus | MTOR | MTOR | 0.00171 | uM | 10874.144 | 1.0095 | 1.0262 | 0.7282 | |
| MX1 | Unknown | Unknown | Temsirolimus | MTOR | MTOR | 0.00853 | uM | 10874.144 | 0.9859 | 0.9615 | 0.7282 | |
| MX1 | Unknown | Unknown | Temsirolimus | MTOR | MTOR | 0.0427 | uM | 10874.144 | 0.9122 | 0.7630 | 0.7282 | |
| MX1 | Unknown | Unknown | Temsirolimus | MTOR | MTOR | 0.213 | uM | 10874.144 | 0.8729 | 0.6595 | 0.7282 | |
| MX1 | Unknown | Unknown | Temsirolimus | MTOR | MTOR | 1.07 | uM | 10874.144 | 0.7707 | 0.3987 | 0.7282 | |
| MX1 | Unknown | Unknown | Temsirolimus | MTOR | MTOR | 5.33 | uM | 10874.144 | 0.7541 | 0.3575 | 0.7282 | |
| MX1 | Unknown | Unknown | Temsirolimus | MTOR | MTOR | 26.7 | uM | 10874.144 | 0.5479 | -0.1247 | 0.7282 | |
| MX1 | Unknown | Unknown | Temsirolimus | MTOR | MTOR | 133 | uM | 10874.144 | 0.0144 | -0.9941 | 0.7282 | |
| MX1 | Unknown | Unknown | Temsirolimus | MTOR | MTOR | 0.000341 | uM | 12220.144 | 0.9130 | 0.6745 | 0.5126 | |
| MX1 | Unknown | Unknown | Temsirolimus | MTOR | MTOR | 0.00171 | uM | 12220.144 | 0.9244 | 0.7155 | 0.5126 | |
| MX1 | Unknown | Unknown | Temsirolimus | MTOR | MTOR | 0.00853 | uM | 12220.144 | 0.8495 | 0.4549 | 0.5126 | |
| MX1 | Unknown | Unknown | Temsirolimus | MTOR | MTOR | 0.0427 | uM | 12220.144 | 0.8237 | 0.3701 | 0.5126 | |
| MX1 | Unknown | Unknown | Temsirolimus | MTOR | MTOR | 0.213 | uM | 12220.144 | 0.8245 | 0.3726 | 0.5126 | |
| MX1 | Unknown | Unknown | Temsirolimus | MTOR | MTOR | 1.07 | uM | 12220.144 | 0.7130 | 0.0337 | 0.5126 | |
| MX1 | Unknown | Unknown | Temsirolimus | MTOR | MTOR | 5.33 | uM | 12220.144 | 0.6955 | -0.0153 | 0.5126 | |
| MX1 | Unknown | Unknown | Temsirolimus | MTOR | MTOR | 26.7 | uM | 12220.144 | 0.3964 | -0.6712 | 0.5126 | |
| MX1 | Unknown | Unknown | Temsirolimus | MTOR | MTOR | 133 | uM | 12220.144 | 0.0789 | -0.9859 | 0.5126 | |
| SK-BR-3 | HER2amp | Luminal | Temsirolimus | MTOR | MTOR | 0.000341 | uM | 11851.144 | 0.8600 | 0.7917 | 1.3716 | |
| SK-BR-3 | HER2amp | Luminal | Temsirolimus | MTOR | MTOR | 0.00171 | uM | 11851.144 | 0.8592 | 0.7905 | 1.3716 | |
| SK-BR-3 | HER2amp | Luminal | Temsirolimus | MTOR | MTOR | 0.00853 | uM | 11851.144 | 0.7935 | 0.6896 | 1.3716 | |
| SK-BR-3 | HER2amp | Luminal | Temsirolimus | MTOR | MTOR | 0.0427 | uM | 11851.144 | 0.5789 | 0.3426 | 1.3716 | |
| SK-BR-3 | HER2amp | Luminal | Temsirolimus | MTOR | MTOR | 0.213 | uM | 11851.144 | 0.5738 | 0.3340 | 1.3716 | |
| SK-BR-3 | HER2amp | Luminal | Temsirolimus | MTOR | MTOR | 1.07 | uM | 11851.144 | 0.5446 | 0.2840 | 1.3716 | |
| SK-BR-3 | HER2amp | Luminal | Temsirolimus | MTOR | MTOR | 5.33 | uM | 11851.144 | 0.4863 | 0.1823 | 1.3716 | |
| SK-BR-3 | HER2amp | Luminal | Temsirolimus | MTOR | MTOR | 26.7 | uM | 11851.144 | 0.4468 | 0.1116 | 1.3716 |