Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)

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Cell Clinical Subtype Transcriptional Subtype Small Molecule Antibody Perturbagen Target Perturbagen Class Perturbagen Concentration Perturbagen Conc Unit Biological Replicate ID Relative Cell Count Normalized Growth Rate Inhibition Value Nominal Division Rate
CAMA-1
HR+
Luminal
TCS PIM-1 1
Pim kinase
PIM
133
uM
10473.135
0.7532 0.5662 1.1592
CAMA-1
HR+
Luminal
TCS PIM-1 1
Pim kinase
PIM
0.000171
uM
10755.148
0.9690 0.9036 0.6379
CAMA-1
HR+
Luminal
TCS PIM-1 1
Pim kinase
PIM
0.000853
uM
10755.148
0.9329 0.7936 0.6379
CAMA-1
HR+
Luminal
TCS PIM-1 1
Pim kinase
PIM
0.00427
uM
10755.148
0.9230 0.7639 0.6379
CAMA-1
HR+
Luminal
TCS PIM-1 1
Pim kinase
PIM
0.0213
uM
10755.148
0.9328 0.7935 0.6379
CAMA-1
HR+
Luminal
TCS PIM-1 1
Pim kinase
PIM
0.107
uM
10755.148
0.9236 0.7658 0.6379
CAMA-1
HR+
Luminal
TCS PIM-1 1
Pim kinase
PIM
0.533
uM
10755.148
0.9172 0.7466 0.6379
CAMA-1
HR+
Luminal
TCS PIM-1 1
Pim kinase
PIM
2.67
uM
10755.148
0.9432 0.8248 0.6379
CAMA-1
HR+
Luminal
TCS PIM-1 1
Pim kinase
PIM
13.3
uM
10755.148
0.9364 0.8043 0.6379
CAMA-1
HR+
Luminal
TCS PIM-1 1
Pim kinase
PIM
66.7
uM
10755.148
0.8422 0.5279 0.6379
CAMA-1
HR+
Luminal
TCS PIM-1 1
Pim kinase
PIM
0.000341
uM
12070.135
0.9369 0.8980 1.2457
CAMA-1
HR+
Luminal
TCS PIM-1 1
Pim kinase
PIM
0.00171
uM
12070.135
0.9665 0.9460 1.2457
CAMA-1
HR+
Luminal
TCS PIM-1 1
Pim kinase
PIM
0.00853
uM
12070.135
0.9153 0.8628 1.2457
CAMA-1
HR+
Luminal
TCS PIM-1 1
Pim kinase
PIM
0.0427
uM
12070.135
1.0159 1.0254 1.2457
CAMA-1
HR+
Luminal
TCS PIM-1 1
Pim kinase
PIM
0.213
uM
12070.135
0.8487 0.7532 1.2457
CAMA-1
HR+
Luminal
TCS PIM-1 1
Pim kinase
PIM
1.07
uM
12070.135
0.9460 0.9128 1.2457
CAMA-1
HR+
Luminal
TCS PIM-1 1
Pim kinase
PIM
5.33
uM
12070.135
0.9445 0.9104 1.2457
CAMA-1
HR+
Luminal
TCS PIM-1 1
Pim kinase
PIM
26.7
uM
12070.135
0.8489 0.7536 1.2457
CAMA-1
HR+
Luminal
TCS PIM-1 1
Pim kinase
PIM
133
uM
12070.135
0.9121 0.8576 1.2457
HCC1143
TNBC
Basal A
TCS PIM-1 1
Pim kinase
PIM
0.000341
uM
12112.135
0.8921 0.8783 1.8185
HCC1143
TNBC
Basal A
TCS PIM-1 1
Pim kinase
PIM
0.00171
uM
12112.135
0.9784 0.9761 1.8185
HCC1143
TNBC
Basal A
TCS PIM-1 1
Pim kinase
PIM
0.00853
uM
12112.135
0.9524 0.9471 1.8185
HCC1143
TNBC
Basal A
TCS PIM-1 1
Pim kinase
PIM
0.0427
uM
12112.135
0.9376 0.9304 1.8185
HCC1143
TNBC
Basal A
TCS PIM-1 1
Pim kinase
PIM
0.213
uM
12112.135
0.9008 0.8884 1.8185
HCC1143
TNBC
Basal A
TCS PIM-1 1
Pim kinase
PIM
1.07
uM
12112.135
0.9948 0.9943 1.8185