Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
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CAMA-1 | HR+ | Luminal | TCS PIM-1 1 | Pim kinase | PIM | 133 | uM | 10473.135 | 0.7532 | 0.5662 | 1.1592 | |
CAMA-1 | HR+ | Luminal | TCS PIM-1 1 | Pim kinase | PIM | 0.000171 | uM | 10755.148 | 0.9690 | 0.9036 | 0.6379 | |
CAMA-1 | HR+ | Luminal | TCS PIM-1 1 | Pim kinase | PIM | 0.000853 | uM | 10755.148 | 0.9329 | 0.7936 | 0.6379 | |
CAMA-1 | HR+ | Luminal | TCS PIM-1 1 | Pim kinase | PIM | 0.00427 | uM | 10755.148 | 0.9230 | 0.7639 | 0.6379 | |
CAMA-1 | HR+ | Luminal | TCS PIM-1 1 | Pim kinase | PIM | 0.0213 | uM | 10755.148 | 0.9328 | 0.7935 | 0.6379 | |
CAMA-1 | HR+ | Luminal | TCS PIM-1 1 | Pim kinase | PIM | 0.107 | uM | 10755.148 | 0.9236 | 0.7658 | 0.6379 | |
CAMA-1 | HR+ | Luminal | TCS PIM-1 1 | Pim kinase | PIM | 0.533 | uM | 10755.148 | 0.9172 | 0.7466 | 0.6379 | |
CAMA-1 | HR+ | Luminal | TCS PIM-1 1 | Pim kinase | PIM | 2.67 | uM | 10755.148 | 0.9432 | 0.8248 | 0.6379 | |
CAMA-1 | HR+ | Luminal | TCS PIM-1 1 | Pim kinase | PIM | 13.3 | uM | 10755.148 | 0.9364 | 0.8043 | 0.6379 | |
CAMA-1 | HR+ | Luminal | TCS PIM-1 1 | Pim kinase | PIM | 66.7 | uM | 10755.148 | 0.8422 | 0.5279 | 0.6379 | |
CAMA-1 | HR+ | Luminal | TCS PIM-1 1 | Pim kinase | PIM | 0.000341 | uM | 12070.135 | 0.9369 | 0.8980 | 1.2457 | |
CAMA-1 | HR+ | Luminal | TCS PIM-1 1 | Pim kinase | PIM | 0.00171 | uM | 12070.135 | 0.9665 | 0.9460 | 1.2457 | |
CAMA-1 | HR+ | Luminal | TCS PIM-1 1 | Pim kinase | PIM | 0.00853 | uM | 12070.135 | 0.9153 | 0.8628 | 1.2457 | |
CAMA-1 | HR+ | Luminal | TCS PIM-1 1 | Pim kinase | PIM | 0.0427 | uM | 12070.135 | 1.0159 | 1.0254 | 1.2457 | |
CAMA-1 | HR+ | Luminal | TCS PIM-1 1 | Pim kinase | PIM | 0.213 | uM | 12070.135 | 0.8487 | 0.7532 | 1.2457 | |
CAMA-1 | HR+ | Luminal | TCS PIM-1 1 | Pim kinase | PIM | 1.07 | uM | 12070.135 | 0.9460 | 0.9128 | 1.2457 | |
CAMA-1 | HR+ | Luminal | TCS PIM-1 1 | Pim kinase | PIM | 5.33 | uM | 12070.135 | 0.9445 | 0.9104 | 1.2457 | |
CAMA-1 | HR+ | Luminal | TCS PIM-1 1 | Pim kinase | PIM | 26.7 | uM | 12070.135 | 0.8489 | 0.7536 | 1.2457 | |
CAMA-1 | HR+ | Luminal | TCS PIM-1 1 | Pim kinase | PIM | 133 | uM | 12070.135 | 0.9121 | 0.8576 | 1.2457 | |
HCC1143 | TNBC | Basal A | TCS PIM-1 1 | Pim kinase | PIM | 0.000341 | uM | 12112.135 | 0.8921 | 0.8783 | 1.8185 | |
HCC1143 | TNBC | Basal A | TCS PIM-1 1 | Pim kinase | PIM | 0.00171 | uM | 12112.135 | 0.9784 | 0.9761 | 1.8185 | |
HCC1143 | TNBC | Basal A | TCS PIM-1 1 | Pim kinase | PIM | 0.00853 | uM | 12112.135 | 0.9524 | 0.9471 | 1.8185 | |
HCC1143 | TNBC | Basal A | TCS PIM-1 1 | Pim kinase | PIM | 0.0427 | uM | 12112.135 | 0.9376 | 0.9304 | 1.8185 | |
HCC1143 | TNBC | Basal A | TCS PIM-1 1 | Pim kinase | PIM | 0.213 | uM | 12112.135 | 0.9008 | 0.8884 | 1.8185 | |
HCC1143 | TNBC | Basal A | TCS PIM-1 1 | Pim kinase | PIM | 1.07 | uM | 12112.135 | 0.9948 | 0.9943 | 1.8185 |