Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Hs 578T | TNBC | Basal B | Oxaliplatin | DNA cross-linker | DNA cross-linker | 0.00805 | uM | 9511.021 | 1.0366 | 1.0541 | 1.3466 | |
| Hs 578T | TNBC | Basal B | Oxaliplatin | DNA cross-linker | DNA cross-linker | 0.0403 | uM | 9511.021 | 1.0728 | 1.1072 | 1.3466 | |
| Hs 578T | TNBC | Basal B | Oxaliplatin | DNA cross-linker | DNA cross-linker | 0.201 | uM | 9511.021 | 1.0039 | 1.0059 | 1.3466 | |
| Hs 578T | TNBC | Basal B | Oxaliplatin | DNA cross-linker | DNA cross-linker | 1.01 | uM | 9511.021 | 0.9771 | 0.9659 | 1.3466 | |
| Hs 578T | TNBC | Basal B | Oxaliplatin | DNA cross-linker | DNA cross-linker | 5.03 | uM | 9511.021 | 0.8020 | 0.6978 | 1.3466 | |
| Hs 578T | TNBC | Basal B | Oxaliplatin | DNA cross-linker | DNA cross-linker | 25.2 | uM | 9511.021 | 0.6690 | 0.4838 | 1.3466 | |
| Hs 578T | TNBC | Basal B | Oxaliplatin | DNA cross-linker | DNA cross-linker | 126 | uM | 9511.021 | 0.3853 | -0.0150 | 1.3466 | |
| Hs 578T | TNBC | Basal B | Oxaliplatin | DNA cross-linker | DNA cross-linker | 629 | uM | 9511.021 | 0.0569 | -0.7620 | 1.3466 | |
| LY2 | HR+ | Luminal | Oxaliplatin | DNA cross-linker | DNA cross-linker | 0.00161 | uM | 9536.011 | 1.0650 | 1.1022 | 1.2640 | |
| LY2 | HR+ | Luminal | Oxaliplatin | DNA cross-linker | DNA cross-linker | 0.00805 | uM | 9536.011 | 0.9727 | 0.9567 | 1.2640 | |
| LY2 | HR+ | Luminal | Oxaliplatin | DNA cross-linker | DNA cross-linker | 0.0403 | uM | 9536.011 | 1.0639 | 1.1004 | 1.2640 | |
| LY2 | HR+ | Luminal | Oxaliplatin | DNA cross-linker | DNA cross-linker | 0.201 | uM | 9536.011 | 1.0056 | 1.0089 | 1.2640 | |
| LY2 | HR+ | Luminal | Oxaliplatin | DNA cross-linker | DNA cross-linker | 1.01 | uM | 9536.011 | 0.7963 | 0.6702 | 1.2640 | |
| LY2 | HR+ | Luminal | Oxaliplatin | DNA cross-linker | DNA cross-linker | 5.03 | uM | 9536.011 | 0.7056 | 0.5178 | 1.2640 | |
| LY2 | HR+ | Luminal | Oxaliplatin | DNA cross-linker | DNA cross-linker | 25.2 | uM | 9536.011 | 0.5772 | 0.2948 | 1.2640 | |
| LY2 | HR+ | Luminal | Oxaliplatin | DNA cross-linker | DNA cross-linker | 126 | uM | 9536.011 | 0.0642 | -0.7720 | 1.2640 | |
| LY2 | HR+ | Luminal | Oxaliplatin | DNA cross-linker | DNA cross-linker | 629 | uM | 9536.011 | 0.0191 | -0.9125 | 1.2640 | |
| LY2 | HR+ | Luminal | Oxaliplatin | DNA cross-linker | DNA cross-linker | 0.00161 | uM | 10264.011 | 0.9995 | 0.9993 | 1.3983 | |
| LY2 | HR+ | Luminal | Oxaliplatin | DNA cross-linker | DNA cross-linker | 0.00805 | uM | 10264.011 | 1.0021 | 1.0030 | 1.3983 | |
| LY2 | HR+ | Luminal | Oxaliplatin | DNA cross-linker | DNA cross-linker | 0.0403 | uM | 10264.011 | 0.9936 | 0.9908 | 1.3983 | |
| LY2 | HR+ | Luminal | Oxaliplatin | DNA cross-linker | DNA cross-linker | 0.201 | uM | 10264.011 | 0.8938 | 0.8457 | 1.3983 | |
| LY2 | HR+ | Luminal | Oxaliplatin | DNA cross-linker | DNA cross-linker | 1.01 | uM | 10264.011 | 0.7003 | 0.5501 | 1.3983 | |
| LY2 | HR+ | Luminal | Oxaliplatin | DNA cross-linker | DNA cross-linker | 5.03 | uM | 10264.011 | 0.5766 | 0.3490 | 1.3983 | |
| LY2 | HR+ | Luminal | Oxaliplatin | DNA cross-linker | DNA cross-linker | 25.2 | uM | 10264.011 | 0.4063 | 0.0503 | 1.3983 | |
| LY2 | HR+ | Luminal | Oxaliplatin | DNA cross-linker | DNA cross-linker | 126 | uM | 10264.011 | 0.1821 | -0.4084 | 1.3983 |