Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC202 | HER2amp | Luminal | Nutlin 3a | MDM2 | MDM2 | 13.3 | uM | 7458.066 | 0.8657 | 0.3574 | 0.3722 | |
| HCC202 | HER2amp | Luminal | Nutlin 3a | MDM2 | MDM2 | 66.7 | uM | 7458.066 | 0.4582 | -0.7543 | 0.3722 | |
| HCC202 | HER2amp | Luminal | Nutlin 3a | MDM2 | MDM2 | 0.000171 | uM | 10470.066 | 1.0093 | 1.0395 | 0.4712 | |
| HCC202 | HER2amp | Luminal | Nutlin 3a | MDM2 | MDM2 | 0.000853 | uM | 10470.066 | 0.9761 | 0.9000 | 0.4712 | |
| HCC202 | HER2amp | Luminal | Nutlin 3a | MDM2 | MDM2 | 0.00427 | uM | 10470.066 | 0.9616 | 0.8406 | 0.4712 | |
| HCC202 | HER2amp | Luminal | Nutlin 3a | MDM2 | MDM2 | 0.0213 | uM | 10470.066 | 0.9942 | 0.9753 | 0.4712 | |
| HCC202 | HER2amp | Luminal | Nutlin 3a | MDM2 | MDM2 | 0.107 | uM | 10470.066 | 1.0416 | 1.1807 | 0.4712 | |
| HCC202 | HER2amp | Luminal | Nutlin 3a | MDM2 | MDM2 | 0.533 | uM | 10470.066 | 0.9845 | 0.9347 | 0.4712 | |
| HCC202 | HER2amp | Luminal | Nutlin 3a | MDM2 | MDM2 | 2.67 | uM | 10470.066 | 1.0380 | 1.1648 | 0.4712 | |
| HCC202 | HER2amp | Luminal | Nutlin 3a | MDM2 | MDM2 | 13.3 | uM | 10470.066 | 1.0114 | 1.0487 | 0.4712 | |
| HCC202 | HER2amp | Luminal | Nutlin 3a | MDM2 | MDM2 | 66.7 | uM | 10470.066 | 0.3040 | -0.8403 | 0.4712 | |
| HCC2185 | TNBC | Luminal | Nutlin 3a | MDM2 | MDM2 | 0.000171 | uM | 7462.066 | 0.9223 | 0.7330 | 0.5644 | |
| HCC2185 | TNBC | Luminal | Nutlin 3a | MDM2 | MDM2 | 0.000853 | uM | 7462.066 | 0.9573 | 0.8511 | 0.5644 | |
| HCC2185 | TNBC | Luminal | Nutlin 3a | MDM2 | MDM2 | 0.00427 | uM | 7462.066 | 0.9583 | 0.8546 | 0.5644 | |
| HCC2185 | TNBC | Luminal | Nutlin 3a | MDM2 | MDM2 | 0.0213 | uM | 7462.066 | 0.9773 | 0.9202 | 0.5644 | |
| HCC2185 | TNBC | Luminal | Nutlin 3a | MDM2 | MDM2 | 0.107 | uM | 7462.066 | 0.9636 | 0.8727 | 0.5644 | |
| HCC2185 | TNBC | Luminal | Nutlin 3a | MDM2 | MDM2 | 0.533 | uM | 7462.066 | 0.9715 | 0.9001 | 0.5644 | |
| HCC2185 | TNBC | Luminal | Nutlin 3a | MDM2 | MDM2 | 2.67 | uM | 7462.066 | 0.9082 | 0.6863 | 0.5644 | |
| HCC2185 | TNBC | Luminal | Nutlin 3a | MDM2 | MDM2 | 13.3 | uM | 7462.066 | 0.8422 | 0.4752 | 0.5644 | |
| HCC2185 | TNBC | Luminal | Nutlin 3a | MDM2 | MDM2 | 66.7 | uM | 7462.066 | 0.5393 | -0.3303 | 0.5644 | |
| HCC2185 | TNBC | Luminal | Nutlin 3a | MDM2 | MDM2 | 0.000171 | uM | 7463.066 | 0.9856 | 0.9484 | 0.5542 | |
| HCC2185 | TNBC | Luminal | Nutlin 3a | MDM2 | MDM2 | 0.000853 | uM | 7463.066 | 0.9865 | 0.9516 | 0.5542 | |
| HCC2185 | TNBC | Luminal | Nutlin 3a | MDM2 | MDM2 | 0.00427 | uM | 7463.066 | 0.9624 | 0.8662 | 0.5542 | |
| HCC2185 | TNBC | Luminal | Nutlin 3a | MDM2 | MDM2 | 0.0213 | uM | 7463.066 | 0.9995 | 0.9982 | 0.5542 | |
| HCC2185 | TNBC | Luminal | Nutlin 3a | MDM2 | MDM2 | 0.107 | uM | 7463.066 | 1.0576 | 1.2127 | 0.5542 |