Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MDA-MB-453 | TNBC | Luminal | GSK1838705A | IGF1R | RTK | 0.533 | uM | 7516.092 | 0.8906 | 0.8006 | 1.1035 | |
| MDA-MB-453 | TNBC | Luminal | GSK1838705A | IGF1R | RTK | 2.67 | uM | 7516.092 | 1.0342 | 1.0618 | 1.1035 | |
| MDA-MB-453 | TNBC | Luminal | GSK1838705A | IGF1R | RTK | 13.3 | uM | 7516.092 | 0.9565 | 0.9210 | 1.1035 | |
| MDA-MB-453 | TNBC | Luminal | GSK1838705A | IGF1R | RTK | 66.7 | uM | 7516.092 | 0.0220 | -0.9370 | 1.1035 | |
| MDA-MB-453 | TNBC | Luminal | GSK1838705A | IGF1R | RTK | 0.000171 | uM | 7516.098 | 0.9577 | 0.9327 | 1.2625 | |
| MDA-MB-453 | TNBC | Luminal | GSK1838705A | IGF1R | RTK | 0.000853 | uM | 7516.098 | 0.8733 | 0.7965 | 1.2625 | |
| MDA-MB-453 | TNBC | Luminal | GSK1838705A | IGF1R | RTK | 0.00427 | uM | 7516.098 | 0.9058 | 0.8492 | 1.2625 | |
| MDA-MB-453 | TNBC | Luminal | GSK1838705A | IGF1R | RTK | 0.0213 | uM | 7516.098 | 0.9158 | 0.8654 | 1.2625 | |
| MDA-MB-453 | TNBC | Luminal | GSK1838705A | IGF1R | RTK | 0.107 | uM | 7516.098 | 0.9725 | 0.9562 | 1.2625 | |
| MDA-MB-453 | TNBC | Luminal | GSK1838705A | IGF1R | RTK | 0.533 | uM | 7516.098 | 0.9134 | 0.8615 | 1.2625 | |
| MDA-MB-453 | TNBC | Luminal | GSK1838705A | IGF1R | RTK | 2.67 | uM | 7516.098 | 0.9972 | 0.9955 | 1.2625 | |
| MDA-MB-453 | TNBC | Luminal | GSK1838705A | IGF1R | RTK | 13.3 | uM | 7516.098 | 0.2249 | -0.3865 | 1.2625 | |
| MDA-MB-453 | TNBC | Luminal | GSK1838705A | IGF1R | RTK | 66.7 | uM | 7516.098 | 0.4065 | -0.0196 | 1.2625 | |
| MDA-MB-453 | TNBC | Luminal | GSK1838705A | IGF1R | RTK | 0.000341 | uM | 7517.091 | 0.9408 | 0.9231 | 1.5552 | |
| MDA-MB-453 | TNBC | Luminal | GSK1838705A | IGF1R | RTK | 0.00171 | uM | 7517.091 | 0.8268 | 0.7698 | 1.5552 | |
| MDA-MB-453 | TNBC | Luminal | GSK1838705A | IGF1R | RTK | 0.00853 | uM | 7517.091 | 0.9951 | 0.9937 | 1.5552 | |
| MDA-MB-453 | TNBC | Luminal | GSK1838705A | IGF1R | RTK | 0.0427 | uM | 7517.091 | 0.9442 | 0.9274 | 1.5552 | |
| MDA-MB-453 | TNBC | Luminal | GSK1838705A | IGF1R | RTK | 0.213 | uM | 7517.091 | 0.9025 | 0.8724 | 1.5552 | |
| MDA-MB-453 | TNBC | Luminal | GSK1838705A | IGF1R | RTK | 1.07 | uM | 7517.091 | 0.8632 | 0.8195 | 1.5552 | |
| MDA-MB-453 | TNBC | Luminal | GSK1838705A | IGF1R | RTK | 5.33 | uM | 7517.091 | 0.8780 | 0.8394 | 1.5552 | |
| MDA-MB-453 | TNBC | Luminal | GSK1838705A | IGF1R | RTK | 26.7 | uM | 7517.091 | 0.1334 | -0.4524 | 1.5552 | |
| MDA-MB-453 | TNBC | Luminal | GSK1838705A | IGF1R | RTK | 133 | uM | 7517.091 | 0.1038 | -0.5339 | 1.5552 | |
| MDA-MB-453 | TNBC | Luminal | GSK1838705A | IGF1R | RTK | 0.000171 | uM | 7517.098 | 1.0442 | 1.0684 | 1.2851 | |
| MDA-MB-453 | TNBC | Luminal | GSK1838705A | IGF1R | RTK | 0.000853 | uM | 7517.098 | 0.9523 | 0.9254 | 1.2851 | |
| MDA-MB-453 | TNBC | Luminal | GSK1838705A | IGF1R | RTK | 0.00427 | uM | 7517.098 | 1.0376 | 1.0583 | 1.2851 |