Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC1806 | TNBC | Basal A | FR180204 | ERK1/2 | MAPK | 0.00128 | uM | 12239.161 | 1.0607 | 1.0661 | 1.8129 | |
| HCC1806 | TNBC | Basal A | FR180204 | ERK1/2 | MAPK | 0.0064 | uM | 12239.161 | 1.0097 | 1.0107 | 1.8129 | |
| HCC1806 | TNBC | Basal A | FR180204 | ERK1/2 | MAPK | 0.032 | uM | 12239.161 | 1.0534 | 1.0582 | 1.8129 | |
| HCC1806 | TNBC | Basal A | FR180204 | ERK1/2 | MAPK | 0.16 | uM | 12239.161 | 1.0529 | 1.0576 | 1.8129 | |
| HCC1806 | TNBC | Basal A | FR180204 | ERK1/2 | MAPK | 0.8 | uM | 12239.161 | 1.0219 | 1.0241 | 1.8129 | |
| HCC1806 | TNBC | Basal A | FR180204 | ERK1/2 | MAPK | 4 | uM | 12239.161 | 1.0621 | 1.0676 | 1.8129 | |
| HCC1806 | TNBC | Basal A | FR180204 | ERK1/2 | MAPK | 20 | uM | 12239.161 | 1.0311 | 1.0341 | 1.8129 | |
| HCC1806 | TNBC | Basal A | FR180204 | ERK1/2 | MAPK | 100 | uM | 12239.161 | 0.5887 | 0.4931 | 1.8129 | |
| HCC1937 | TNBC | Basal A | FR180204 | ERK1/2 | MAPK | 0.000256 | uM | 11849.161 | 1.0417 | 1.0651 | 1.2764 | |
| HCC1937 | TNBC | Basal A | FR180204 | ERK1/2 | MAPK | 0.00128 | uM | 11849.161 | 1.0461 | 1.0719 | 1.2764 | |
| HCC1937 | TNBC | Basal A | FR180204 | ERK1/2 | MAPK | 0.0064 | uM | 11849.161 | 1.0651 | 1.1013 | 1.2764 | |
| HCC1937 | TNBC | Basal A | FR180204 | ERK1/2 | MAPK | 0.032 | uM | 11849.161 | 1.0097 | 1.0151 | 1.2764 | |
| HCC1937 | TNBC | Basal A | FR180204 | ERK1/2 | MAPK | 0.16 | uM | 11849.161 | 1.1003 | 1.1555 | 1.2764 | |
| HCC1937 | TNBC | Basal A | FR180204 | ERK1/2 | MAPK | 0.8 | uM | 11849.161 | 1.0670 | 1.1042 | 1.2764 | |
| HCC1937 | TNBC | Basal A | FR180204 | ERK1/2 | MAPK | 4 | uM | 11849.161 | 1.1423 | 1.2198 | 1.2764 | |
| HCC1937 | TNBC | Basal A | FR180204 | ERK1/2 | MAPK | 20 | uM | 11849.161 | 1.0346 | 1.0539 | 1.2764 | |
| HCC1937 | TNBC | Basal A | FR180204 | ERK1/2 | MAPK | 100 | uM | 11849.161 | 0.7712 | 0.6317 | 1.2764 | |
| HCC1954 | HER2amp | Basal A | FR180204 | ERK1/2 | MAPK | 0.0000853 | uM | 11055.149 | 0.9586 | 0.9500 | 1.6723 | |
| HCC1954 | HER2amp | Basal A | FR180204 | ERK1/2 | MAPK | 0.000427 | uM | 11055.149 | 0.9752 | 0.9702 | 1.6723 | |
| HCC1954 | HER2amp | Basal A | FR180204 | ERK1/2 | MAPK | 0.00213 | uM | 11055.149 | 1.0010 | 1.0012 | 1.6723 | |
| HCC1954 | HER2amp | Basal A | FR180204 | ERK1/2 | MAPK | 0.0107 | uM | 11055.149 | 0.9645 | 0.9573 | 1.6723 | |
| HCC1954 | HER2amp | Basal A | FR180204 | ERK1/2 | MAPK | 0.0533 | uM | 11055.149 | 0.9537 | 0.9441 | 1.6723 | |
| HCC1954 | HER2amp | Basal A | FR180204 | ERK1/2 | MAPK | 0.267 | uM | 11055.149 | 0.9436 | 0.9318 | 1.6723 | |
| HCC1954 | HER2amp | Basal A | FR180204 | ERK1/2 | MAPK | 1.33 | uM | 11055.149 | 0.9372 | 0.9239 | 1.6723 | |
| HCC1954 | HER2amp | Basal A | FR180204 | ERK1/2 | MAPK | 6.67 | uM | 11055.149 | 0.8972 | 0.8743 | 1.6723 |