Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC1937 | TNBC | Basal A | Fascaplysin | CDK4 | CDK | 0.267 | uM | 7453.084 | 0.7869 | 0.7151 | 1.5592 | |
| HCC1937 | TNBC | Basal A | Fascaplysin | CDK4 | CDK | 1.33 | uM | 7453.084 | 0.1219 | -0.4815 | 1.5592 | |
| HCC1937 | TNBC | Basal A | Fascaplysin | CDK4 | CDK | 6.67 | uM | 7453.084 | 0.0093 | -0.9005 | 1.5592 | |
| HCC1937 | TNBC | Basal A | Fascaplysin | CDK4 | CDK | 33.3 | uM | 7453.084 | 0.0054 | -0.9298 | 1.5592 | |
| HCC1954 | HER2amp | Basal A | Fascaplysin | CDK4 | CDK | 0.0000853 | uM | 7456.084 | 1.0473 | 1.0472 | 1.9822 | |
| HCC1954 | HER2amp | Basal A | Fascaplysin | CDK4 | CDK | 0.000427 | uM | 7456.084 | 0.9532 | 0.9522 | 1.9822 | |
| HCC1954 | HER2amp | Basal A | Fascaplysin | CDK4 | CDK | 0.00213 | uM | 7456.084 | 0.9570 | 0.9562 | 1.9822 | |
| HCC1954 | HER2amp | Basal A | Fascaplysin | CDK4 | CDK | 0.0107 | uM | 7456.084 | 1.0317 | 1.0317 | 1.9822 | |
| HCC1954 | HER2amp | Basal A | Fascaplysin | CDK4 | CDK | 0.0533 | uM | 7456.084 | 0.9648 | 0.9642 | 1.9822 | |
| HCC1954 | HER2amp | Basal A | Fascaplysin | CDK4 | CDK | 0.267 | uM | 7456.084 | 0.6644 | 0.6272 | 1.9822 | |
| HCC1954 | HER2amp | Basal A | Fascaplysin | CDK4 | CDK | 1.33 | uM | 7456.084 | 0.0226 | -0.7044 | 1.9822 | |
| HCC1954 | HER2amp | Basal A | Fascaplysin | CDK4 | CDK | 6.67 | uM | 7456.084 | 0.0094 | -0.8105 | 1.9822 | |
| HCC1954 | HER2amp | Basal A | Fascaplysin | CDK4 | CDK | 33.3 | uM | 7456.084 | 0.0045 | -0.8694 | 1.9822 | |
| HCC1954 | HER2amp | Basal A | Fascaplysin | CDK4 | CDK | 0.0000853 | uM | 7457.084 | 0.9488 | 0.9441 | 1.8520 | |
| HCC1954 | HER2amp | Basal A | Fascaplysin | CDK4 | CDK | 0.000427 | uM | 7457.084 | 0.9989 | 0.9988 | 1.8520 | |
| HCC1954 | HER2amp | Basal A | Fascaplysin | CDK4 | CDK | 0.00213 | uM | 7457.084 | 0.9385 | 0.9326 | 1.8520 | |
| HCC1954 | HER2amp | Basal A | Fascaplysin | CDK4 | CDK | 0.0107 | uM | 7457.084 | 0.9483 | 0.9435 | 1.8520 | |
| HCC1954 | HER2amp | Basal A | Fascaplysin | CDK4 | CDK | 0.0533 | uM | 7457.084 | 0.9553 | 0.9512 | 1.8520 | |
| HCC1954 | HER2amp | Basal A | Fascaplysin | CDK4 | CDK | 0.267 | uM | 7457.084 | 0.5995 | 0.5173 | 1.8520 | |
| HCC1954 | HER2amp | Basal A | Fascaplysin | CDK4 | CDK | 1.33 | uM | 7457.084 | 0.0092 | -0.8412 | 1.8520 | |
| HCC1954 | HER2amp | Basal A | Fascaplysin | CDK4 | CDK | 6.67 | uM | 7457.084 | 0.0085 | -0.8479 | 1.8520 | |
| HCC1954 | HER2amp | Basal A | Fascaplysin | CDK4 | CDK | 33.3 | uM | 7457.084 | 0.0061 | -0.8722 | 1.8520 | |
| HCC202 | HER2amp | Luminal | Fascaplysin | CDK4 | CDK | 0.0000853 | uM | 7458.084 | 1.0664 | 1.2409 | 0.5653 | |
| HCC202 | HER2amp | Luminal | Fascaplysin | CDK4 | CDK | 0.000427 | uM | 7458.084 | 1.0424 | 1.1524 | 0.5653 | |
| HCC202 | HER2amp | Luminal | Fascaplysin | CDK4 | CDK | 0.00213 | uM | 7458.084 | 0.9912 | 0.9690 | 0.5653 |