Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| BT-474 | HER2amp | Luminal | Doxorubicin | TOP2 | TOP | 0.00118 | uM | 7798.077 | 0.9853 | 0.9795 | 1.4371 | |
| BT-474 | HER2amp | Luminal | Doxorubicin | TOP2 | TOP | 0.00589 | uM | 7798.077 | 1.0679 | 1.0935 | 1.4371 | |
| BT-474 | HER2amp | Luminal | Doxorubicin | TOP2 | TOP | 0.0294 | uM | 7798.077 | 0.9861 | 0.9806 | 1.4371 | |
| BT-474 | HER2amp | Luminal | Doxorubicin | TOP2 | TOP | 0.147 | uM | 7798.077 | 1.0692 | 1.0954 | 1.4371 | |
| BT-474 | HER2amp | Luminal | Doxorubicin | TOP2 | TOP | 0.736 | uM | 7798.077 | 0.5206 | 0.2700 | 1.4371 | |
| BT-474 | HER2amp | Luminal | Doxorubicin | TOP2 | TOP | 3.68 | uM | 7798.077 | 0.7247 | 0.5985 | 1.4371 | |
| BT-474 | HER2amp | Luminal | Doxorubicin | TOP2 | TOP | 18.4 | uM | 7798.077 | 0.7292 | 0.6054 | 1.4371 | |
| BT-474 | HER2amp | Luminal | Doxorubicin | TOP2 | TOP | 92 | uM | 7798.077 | 0.0160 | -0.8874 | 1.4371 | |
| BT-474 | HER2amp | Luminal | Doxorubicin | TOP2 | TOP | 0.000221 | uM | 9157.034 | 1.0561 | 1.1058 | 1.0593 | |
| BT-474 | HER2amp | Luminal | Doxorubicin | TOP2 | TOP | 0.0011 | uM | 9157.034 | 0.9889 | 0.9791 | 1.0593 | |
| BT-474 | HER2amp | Luminal | Doxorubicin | TOP2 | TOP | 0.00552 | uM | 9157.034 | 0.9957 | 0.9920 | 1.0593 | |
| BT-474 | HER2amp | Luminal | Doxorubicin | TOP2 | TOP | 0.0276 | uM | 9157.034 | 0.9689 | 0.9413 | 1.0593 | |
| BT-474 | HER2amp | Luminal | Doxorubicin | TOP2 | TOP | 0.138 | uM | 9157.034 | 0.9052 | 0.8206 | 1.0593 | |
| BT-474 | HER2amp | Luminal | Doxorubicin | TOP2 | TOP | 0.69 | uM | 9157.034 | 0.3253 | -0.3071 | 1.0593 | |
| BT-474 | HER2amp | Luminal | Doxorubicin | TOP2 | TOP | 3.45 | uM | 9157.034 | 0.6191 | 0.2718 | 1.0593 | |
| BT-474 | HER2amp | Luminal | Doxorubicin | TOP2 | TOP | 17.2 | uM | 9157.034 | 0.5256 | 0.0898 | 1.0593 | |
| BT-474 | HER2amp | Luminal | Doxorubicin | TOP2 | TOP | 86.2 | uM | 9157.034 | 0.0065 | -0.9828 | 1.0593 | |
| BT-474 | HER2amp | Luminal | Doxorubicin | TOP2 | TOP | 0.000236 | uM | 9158.121 | 0.9732 | 0.9499 | 1.0691 | |
| BT-474 | HER2amp | Luminal | Doxorubicin | TOP2 | TOP | 0.00118 | uM | 9158.121 | 1.0207 | 1.0387 | 1.0691 | |
| BT-474 | HER2amp | Luminal | Doxorubicin | TOP2 | TOP | 0.00589 | uM | 9158.121 | 1.0202 | 1.0378 | 1.0691 | |
| BT-474 | HER2amp | Luminal | Doxorubicin | TOP2 | TOP | 0.0294 | uM | 9158.121 | 1.0344 | 1.0643 | 1.0691 | |
| BT-474 | HER2amp | Luminal | Doxorubicin | TOP2 | TOP | 0.147 | uM | 9158.121 | 1.0709 | 1.1324 | 1.0691 | |
| BT-474 | HER2amp | Luminal | Doxorubicin | TOP2 | TOP | 0.736 | uM | 9158.121 | 0.0604 | -0.8552 | 1.0691 | |
| BT-474 | HER2amp | Luminal | Doxorubicin | TOP2 | TOP | 3.68 | uM | 9158.121 | 0.6297 | 0.2977 | 1.0691 | |
| BT-474 | HER2amp | Luminal | Doxorubicin | TOP2 | TOP | 18.4 | uM | 9158.121 | 0.4835 | 0.0134 | 1.0691 |