Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)

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Cell Clinical Subtype Transcriptional Subtype Small Molecule Antibody Perturbagen Target Perturbagen Class Perturbagen Concentration Perturbagen Conc Unit Biological Replicate ID Relative Cell Count Normalized Growth Rate Inhibition Value Nominal Division Rate
AU565
HER2amp
Luminal
Doxorubicin
TOP2
TOP
0.0276
uM
7793.007
0.9547 0.9341 1.3832
AU565
HER2amp
Luminal
Doxorubicin
TOP2
TOP
0.138
uM
7793.007
0.5470 0.2930 1.3832
AU565
HER2amp
Luminal
Doxorubicin
TOP2
TOP
0.69
uM
7793.007
0.1182 -0.5728 1.3832
AU565
HER2amp
Luminal
Doxorubicin
TOP2
TOP
3.45
uM
7793.007
0.0125 -0.9157 1.3832
AU565
HER2amp
Luminal
Doxorubicin
TOP2
TOP
17.2
uM
7793.007
0.0095 -0.9308 1.3832
AU565
HER2amp
Luminal
Doxorubicin
TOP2
TOP
86.2
uM
7793.007
0.0056 -0.9529 1.3832
AU565
HER2amp
Luminal
Doxorubicin
TOP2
TOP
0.000236
uM
9035.077
0.9781 0.9816 2.3909
AU565
HER2amp
Luminal
Doxorubicin
TOP2
TOP
0.00118
uM
9035.077
1.0182 1.0152 2.3909
AU565
HER2amp
Luminal
Doxorubicin
TOP2
TOP
0.00589
uM
9035.077
1.0335 1.0277 2.3909
AU565
HER2amp
Luminal
Doxorubicin
TOP2
TOP
0.0294
uM
9035.077
0.9811 0.9841 2.3909
AU565
HER2amp
Luminal
Doxorubicin
TOP2
TOP
0.147
uM
9035.077
0.3275 0.2540 2.3909
AU565
HER2amp
Luminal
Doxorubicin
TOP2
TOP
0.736
uM
9035.077
0.0912 -0.2653 2.3909
AU565
HER2amp
Luminal
Doxorubicin
TOP2
TOP
3.68
uM
9035.077
0.0063 -0.7602 2.3909
AU565
HER2amp
Luminal
Doxorubicin
TOP2
TOP
18.4
uM
9035.077
0.0021 -0.8469 2.3909
AU565
HER2amp
Luminal
Doxorubicin
TOP2
TOP
92
uM
9035.077
0.0007 -0.9043 2.3909
AU565
HER2amp
Luminal
Doxorubicin
TOP2
TOP
0.000236
uM
9146.121
1.0280 1.0492 1.1366
AU565
HER2amp
Luminal
Doxorubicin
TOP2
TOP
0.00118
uM
9146.121
0.9685 0.9444 1.1366
AU565
HER2amp
Luminal
Doxorubicin
TOP2
TOP
0.00589
uM
9146.121
0.8009 0.6452 1.1366
AU565
HER2amp
Luminal
Doxorubicin
TOP2
TOP
0.0294
uM
9146.121
0.9607 0.9306 1.1366
AU565
HER2amp
Luminal
Doxorubicin
TOP2
TOP
0.147
uM
9146.121
0.6065 0.2882 1.1366
AU565
HER2amp
Luminal
Doxorubicin
TOP2
TOP
0.736
uM
9146.121
0.1244 -0.6804 1.1366
AU565
HER2amp
Luminal
Doxorubicin
TOP2
TOP
3.68
uM
9146.121
0.0131 -0.9559 1.1366
AU565
HER2amp
Luminal
Doxorubicin
TOP2
TOP
18.4
uM
9146.121
0.0076 -0.9726 1.1366
AU565
HER2amp
Luminal
Doxorubicin
TOP2
TOP
92
uM
9146.121
0.0026 -0.9894 1.1366
BT-474
HER2amp
Luminal
Doxorubicin
TOP2
TOP
0.000236
uM
7798.077
1.0126 1.0175 1.4371